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Risk factor control in patients with Type 2 diabetes and coronary heart disease: findings from the Swedish National Diabetes Register (NDR)

Patients with Type 2 diabetes and coronary heart disease (CHD) are infrequently treated to risk factor targets in current guidelines. We aimed to examine risk factor management and control levels in a large sample of patients with Type 2 diabetes with CHD. This was an observational study of 1612 patients with first incidence of CHD before 2002, and of 4570 patients with first incidence of CHD befo

The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis

Background. In metastatic colorectal cancer, mutation testing for KRAS exon 2 is widely implemented to select patients with wild-type tumors for treatment with the monocloncal anti-EGFR antibodies cetuximab and panitumumab. The added predictive value of additional biomarkers in the RAS-RAF-MAPK and PI3K-AKT-mTOR pathways in colorectal cancer is uncertain, which led us to systematically review the

Experimental verification of degrees of freedom for co-located antennas in wireless channels

It has been postulated that six co-located orthogonally polarized electrical and magnetic dipoles can offer up to six degrees of freedom (DOFs) in a multipath scattering environment. In other words, a six-fold increase in channel capacity can be achieved in the context of MIMO systems. However, due to the complexity in designing and measuring such a six-port antenna, to our knowledge, no experimen

Organometal Halide Perovskite Solar Cell Materials Rationalized: Ultrafast Charge Generation, High and Microsecond-Long Balanced Mobilities, and Slow Recombination

Organometal halide perovskite-based solar cells have recently been reported to be highly efficient, giving an overall power conversion efficiency of up to 15%. However, much of the fundamental photophysical properties underlying this performance has remained unknown. Here, we apply photoluminescence, transient absorption, time-resolved terahertz and microwave conductivity measurements to determine

Size and Morphology of Assemblies Formed by DNA and Lysozyme in Dilute Aqueous Mixtures

Assemblies formed by a well-defined quality of DNA (4331 bp T7 DNA) and the small net-cationic protein lysozyme in dilute aqueous solutions have been characterized using cryo-transmission electron microscopy (cryo-TEM) and dynamic light scattering (DLS) as the main techniques. In a wide range of different DNA to lysozyme ratios in solutions of low ionic strength, dispersions of aggregates with the

Fine root dynamics along an elevational gradient in tropical Amazonian and Andean forests

The key role of tropical forest belowground carbon stocks and fluxes is well recognised as one of the main components of the terrestrial ecosystem carbon cycle. This study presents the first detailed investigation of spatial and temporal patterns of fine root stocks and fluxes in tropical forests along an elevational gradient, ranging from the Peruvian Andes (3020 m) to lowland Amazonia (194 m), w

A Developmental Approach to Assessing and Treating Agrammatic Aphasia

Purpose: There is mounting evidence that the agrammatism that defines Broca’s aphasia can be explained in processing terms. However, the extant approach simply describes agrammatism as disparate deficits in a static, mature system. This tutorial aims to motivate and outline a developmental alternative. This alternative is processability theory (PT), a root-to-apex theory of language development, w

Äga rum: Offentliga rum betraktade i ett politiskt perspektiv, fallet Pristina

In order to fully grasp the phenomena 'City' we must understand its political structure as an integrated part of its physical structure and vice versa. This thesis focuses on one crucial element of the City, the public space, and discusses it in relation to the public realm, or sphere, of the City. The aim is to see if it is possible to conceive public space as a spatial dimension of power

Which model generates the best predictions on the future spot rate?– a comparison between three different forms of the UIP model

There are many empirical studies that reject the forecasting power of the uncovered interest rate parity condition. This might be due to different reasons, of which one often stated is the existence of a risk premium. In this paper three versions of the conventional UIP model are tested in order to investigate which one that generates the best predictions on the future spot rate. One model without

Ung? Var god dröj! En diskursanalys kring ungdomsarbetslöshet och fördröjd etablering på arbetsmarknaden

Youth unemployement in Sweden is at an all-time high, a fifth of all university and college students live in poverty and the number of young on welfare is increasing. This study attempts to answer the question of how youth deprivation has been made possible as a consequence of political action, focusing on youth unemployment. I critically examine the role of the Swedish government, the Swedish La

Cyberspace and Political Participation in Contemporary China : A Preliminary Assessment Based on Two Case Studies

This paper approaches information technology and the Internet's social and political impact in contemporary China from the perspective of political participation. This paper applies the "public sphere" concept as an analytical tool to define the relationship between public sphere and the newly rising cyberspace. It finds that certain part of cyberspace is the relevant reflection of p

ALTERNATIVE LIFESTYLE CHOICES : JAPANESE SNOWBOARDERS IN NEW ZEALAND

There is a debate in Japan which focuses on the lifestyle choices of young Japanese. The elder generation think youth are being selfish and not making a sufficient contribution to society in that they are not conforming to traditional societal expectations. However, it is not so easy to contribute to society when youth have been hit particularly hard by unemployment, changing recruitment practice

Vildagliptin Reduces Glucagon during Hyperglycemia and Sustains Glucagon Counterregulation during Hypoglycemia in Type 1 Diabetes.

Context: The dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits glucagon secretion at hyperglycemia but appears to enhance glucagon counterregulation during hypoglycemia in type 2 diabetes.Objective:The objective of the investigation was to study whether vildagliptin also improves α-cell function in type 1 diabetes (T1D). Patients and Methods: The study was a single-center, double-blind, ra

Comfort and Safety as Perceived by Wheelchair-Seated Bus Passengers

Wheelchair-seated passengers on European and Swedish urban transit buses can travel rearwards, resting against a bulkhead, without the use of tiedown equipment. However, users sometimes disapprove of being the only passengers who have to travel rearwards, and also unrestrained. In order to investigate comfort and safety as perceived by wheelchair-seated bus passengers riding either forwards or rea

Collagenase treatment of Dupuytren's contracture using a modified injection method

Background and purpose - Treatment of Dupuytren's contracture (DC) with collagenase Clostridium histolyticum (CCH) consists of injection followed by finger manipulation. We used a modified method, injecting a higher dose than recommended on the label into several parts of the cord, which allows treatment of multiple joint contractures in 1 session and may increase efficacy. We studied the occurren

Separation of dispersed substances and galactoglucomannan in thermomechanical pulp process water by microfiltration

Several valuable substances are released from wood during the production of thermomechanical pulp. These substances can be isolated and purified for use as value-added chemicals. The hemicellulose galactoglucomannan (GGM) has attracted a great deal of interest because of its possible applications as an oxygen barrier film in packaging materials, as a hydrogel in biomedical products and as an emuls

Dense resistivity and induced polarization profiling for a landfill restoration project at Harlov, Southern Sweden

A resistivity and time-domain induced polarization (IP) survey was conducted at a landfill Site under restoration at Harlov in Southern Sweden. The covering of the landfill had begun some years ago, without keeping precise records of the work done, as is usual in such procedures. The survey was conducted in two steps, on two adjacent areas. First, a number of geoelectrical sections were made on a

Quarrying for Augustus: Gebel el-Silsila as a Source for Early Roman Monuments at Dendera

This paper presents a selection of epigraphic documents dispersed over three quarry faces (C11–C13) in the Main Quarry (Q34) at Gebel el-Silsila’s east bank, dating from the reign of the Emperor Augustus. The aim is to describe and decipher the various marks and depictions, and to translate the Demotic and Greek texts, in order to determine for what structure the stone from the quarry was intendedThis paper presents a selection of epigraphic documents dispersed over three quarry faces (C11–C13) in the Main Quarry (Q34) at Gebel el-Silsila’s east bank, dating from the reign of the Emperor Augustus. The aim is to describe and decipher the various marks and depictions, and to translate the Demotic and Greek texts, in order to determine for what structure the stone from the quarry was intended

Mellan kamp och samförstånd: den könspolitiska debatten i Svenska Kommunalarbetareförbundet 1958-2006

The field of labour history has come to increasingly include the study of gender, a social relation that traditionally has been made invisible. At the same time the past decades of theoretical debate within gender studies and history have meant the marginalisation of class studies, at the benefit of other social relations. I wish to contribute to the field of research on the Swedish labour union m