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Enhancers are central regulators of cell-type-specific gene expression, yet direct functional mapping of active enhancer-promoter interactions in single cells remains technically challenging. DNA adenine methyltransferase (Dam)-based chromatin recording offers a strategy to mark genomic regions proximal to proteins associated with active transcription sites in vivo, including enhancer regions, and

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Denna studie är en fallstudie av en byggnad belägen i Malmö, Sverige, som undersöker olika energieffektiva åtgärder och deras potentiella påverkan på byggnadens energikonsumtion. En förstudie genomfördes för att inhämta kunskap om tillämpliga energieffektiva åtgärder från befintlig forskning. Därefter genomfördes fallstudien i tre huvudsakliga faser. I den första fasen samlades byggnadsinformationThis study is a single case study of a building situated in Malmö, Sweden, examining various retrofit measures and their potential impact on the building’s energy performance. A pre-study was carried out to gain knowledge on applicable retrofitting measures from existing literature. Subsequently, the case study consisted of three major phases. In the first phase, building information was collected

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The objective of this research was to explore and enhance the comprehension of the methods employed in social work concerning children and youth in flight. Additionally, it investigated the key considerations in social work with children and youth in flight to Sweden, as well as the specific measures implemented in the handling process for this particular demographic. The study delved into various

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Denna uppsats undersöker Europeiska domstolen för de mänskliga rättigheternas (Europadomstolen) praxis gällande rättigheter för trans- och intersexpersoner, inkluderat rätten till icke-diskriminering, mot bakgrund av Sandra Fredmans fyrdimensionella teori om reell jämlikhet (substantive equality). Även om domstolen historiskt sett har strävat efter att främja och skydda transpersoners rättigheter,This thesis examines the European Court of Human Rights’ jurisprudence on trans and intersex rights, including the right to non-discrimination, in the light of Sandra Fredman’s four-dimensional theoretical framework on substantive equality. While the Court historically has made some strives in promoting and protecting the rights of trans people, considerations of non-discrimination and equality ha

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Abstract Title: Project managers – The invisible leaders Authors: Stefan Karlsson and Christoffer Karlsson Supervisor: Radhlinah Aulin, Division of Construction Management, Lund Faculty of Engineering Problem: * What are the most important work tasks for a project manager * What are the most important skills in the role as a project manager * What kind of common problems and difficulties are a pro

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Today, semi-conductor nanowires can be grown with very high precision, using epitaxy. This allows for studies of new nanowire-based quantum devices, likely to be part of novel quantum technologies in the future. This thesis concerns nanostructures based on InAs nanowires. More specifically, it concerns the theoretical treatment of two types of nanowire-based structures: InAs/GaSb core-shell (and c

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Background and objectives: Beans (Phaseolus vulgaris L.) are widely consumed, but the bioaccessibility of their phenolic compounds (PCs) may be affected by different factors. Within this framework, an in vitro gastrointestinal digestion of two bean varieties: “Azufrado” and “Negro Jamapa,” was performed and the bioaccessibility and in vitro release kinetics of PC was evaluated. Mashed beans were p

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In the interstellar medium polycyclic aromatic hydrocarbon molecules (PAH) are exposed to strong ionizing radation leading to complex organic photochemistry. We investigated these ultrafast fragmentation reac-tions after ionization of the PAHs phenanthrene, fluorene and pyrene at a wavelength of 30.3 nm using pump probe spectroscopy at a free electron laser. We observe double ionization and afterw

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Context. The HR 1614 is an overdensity in velocity space and has for a long time been known as an old (2 Gyr) and metal-rich ([Fe=H] +0:2) nearby moving group that has a dissolving open cluster origin. The existence of such old and metal-rich groups in the solar vicinity is quite unexpected since the vast majority of nearby moving groups are known to be young. Aims. In the light of new and signifi

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Background and objective: New proposals to improve the regulation of hypnosis in anaesthesia based on the development of advanced control structures emerge continuously. However, a fair study to analyse the real benefits of these structures compared to simpler clinically validated PID-based solutions has not been presented so far. The main objective of this work is to analyse the performance limit

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Background: the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably since then and it has therefore become necessary to update these recommendations.Methods: under the auspices of the UEMS-GMS, the European Geriatric Medicine Society (EuGMS) and the European Academy

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The parameters to extract polysaccharide-enriched fractions (PEF) from mushrooms using MAE (microwave-assisted extraction) were adjusted following a full factorial 3 2 experimental design. The highest yield and total carbohydra

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We present high-order harmonic generation results obtained with different laser systems a 1 ps 1053 nm Nd-glass laser a 2 ps 616 nm synchronously pumped dye laser a 36 ps 1064 nm mode-locked Nd-YAG laser and the second harmonics (308 nm and 532 nm) of the latter two systems. We investigate the influence of the laser pulse width the excitation wavelength (from the near infrared to the ultraviolet)

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Recent advancements in catchment hydrology (such as understanding hydrological processes, accessing new data sources, and refining methods for parameter constraints) make it possible to apply catchment models for ungauged basins over large domains. Here we present a cutting-edge case study applying catchment-modelling techniques at the global scale for the first time. The modelling procedure was c