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Antimicrobial peptides are important effector molecules of the innate immune system. Here, we describe that peptides derived from the heparin-binding disulfide-constrained loop region of human ß-amyloid precursor protein are antimicrobial. The peptides investigated were linear and cyclic forms of NWCKRGRKQCKTHPH (NWC15) as well as the cyclic form comprising the C-terminal hydrophobic amino acid ex
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Water calorimetric measurements have been performed in a 180 MeV scanned pulsed proton beam and the absorbed dose determined has been compared with the results obtained using two NE2571 Farmer chambers and the IAEA TRS-398 code of practice. The depth of measurement in water corresponded to a residual range of R-res = 16.5 cm, corresponding to a mean energy of about 150 MeV. Ionization chambers wer
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Time-resolved spectroscopy in the visible and near-infrared (NIR) regions was used in a feasibility study for analysis of solid pharmaceuticals. The objective of the experiments was to study the interaction of light with pharmaceutical solids and to investigate the usefulness of the method as an analytical toot for spectroscopic analysis. In these experiments, a pulsed Ti:sapphire laser and white
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To mitigate climate change and reach Sweden’s goal of becoming carbon neutral by 2045, or at an earlier stage of 2030 for 23 Swedish cities, urgent action is required to reduce greenhouse gas emissions. Due to the building sector’s significant contribution to carbon emissions, a crucial aspect in achieving these goals is improving the energy efficiency of existing buildings, as most of these will
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This thesis is written as an introductory compilation of two-dimensional electronic spectroscopy (2DES) and its applications. It introduces the concepts of 2DES where the aim is to provide an overview of the technique and a few of its more prominent applications for those who are not already familiar with the technique. 2DES is a third-order optics technique that utilizes three interactions with l
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A product with the need for a wireless communication between itself and a smartphone will be developed. A suitable wireless protocol and module will be chosen and evaluated. How should the software be designed? What functions should be available? In the end the module and software will be tested in the field to see how it works in reality. For the choosing of protocol, the following will be discus
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Ämnesplanen i svenska i gymnasiet ska bygga på men inte överlappa kursplanen i svenska i grundskolan. Grammatiken beskrivs endast implicit i Svenska 1 och omnämns explicit först i Svenska 2. Detta innebär att grammatikundervisning och metaspråk i svenskämnet på gymnasiet i hög grad är beroende av elevernas grammatiska förkunskaper från grundskolan. Syftet var att undersöka hur svensklärare hanteraThe syllabus in Swedish in upper secondary school should be based on, but not overlap, the syllabus in Swedish in primary school. Grammar is only implicitly described in Swedish 1 and is explicitly mentioned only once you move on to Swedish 2. This means that grammar teaching and metalanguage in Swedish in upper secondary school is to a large extent dependent on the students' prior grammatical
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In this study, characterization of the binding kinetics and optimization of a magnetic permeability based point-of-care (POC) immunoassay system for quantification of canine C-reactive protein (cCRP) is described. The reagent is based on a two-site heterogeneous immunoassay system utilizing conjugated superparamagnetic nanoparticles (SPION) and silica particles, both particles carrying covalently
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Previous studies have suggested that the development of diabetes in the BB rats does not require the expression of T lymphopenia. In order to derive non-lymphopenic diabetic rats and define the relationship between the T cell abnormalities, MHC genotype, and diabetes, we performed a cross between BB/H and diabetes resistant BB/control followed by an intercross of the F1. In the F2, the overall inc
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Carpal tunnel syndrome (CTS) is a common cause of work disability. The association with occupational load and education level has not been established in general-population studies. The purpose of this study was to investigate the association of clinically relevant CTS with work and education. From the Healthcare Register of Skane region (population 1.2 million) in southern Sweden we identified al
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In this review we cover and describe the application of grazing incidence x-ray scattering techniques to study and characterize nanopattern formation on semiconductor surfaces by ion beam erosion under various conditions. It is demonstrated that x-rays under grazing incidence are especially well suited to characterize (sub)surface structures on the nanoscale with high spatial and statistical accur
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Credibility assessment of testimony is a very important part in the asylum adjudication procedure. The credibility assessment is intended to tell decision-makers whether they should accept the facts as supported by the applicant’s statement. Only those parts of the statement which are recognized as credible will then be considered in determining the validity of the asylum claim. This thesis exam
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Public sector services are audited, measured and ranked in order to improve quality and transparency and to prompt organizations to conform to normative definitions of quality. In Swedish eldercare, a nationwide user survey distributed by the public authorities to all eldercare users, designed to gauge user satisfaction, is a prominent example of this form of soft governance. The aim of the presen
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The meteoritic material falling on Earth is believed to derive from large break-up or cratering events in the asteroid belt. The flux of extraterrestrial material would then vary in accordance with the timing of such asteroid family-forming events. In order to validate this, we investigated marine sediments representing 15 time-windows in the Phanerozoic for content of micrometeoritic relict chrom
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The evolution of globular star clusters tells the history of the formation of galaxies, how stellar streams might have formed and how the future of the Universe might look like. Although the general theoretical background of the evolution is well understood, it is difficult to conduct accurate and realistic computer simulations of objects containing thousands of interacting bodies. This project in
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Det finns virtuell egendom i videospel med verkliga förmögenhetsvärden, varför den här undersökningen syftar till att utreda om denna företeelse är tjänlig som kreditsäkerhetsobjekt vid pantsättning i svensk rätt. För att uppfylla uppsatsens syfte används en rättsdogmatisk, och till viss del även en komparativ metod, tillsammans med både svenskt och utländskt material. Virtuell egendom är en företVirtual property in videogames with real monetary value is a reality. The purpose of this paper is to assess whether virtual property may be pledged in a credit transaction. This issue is addressed using both the Swedish legal dogmatic method (Sw. rättsdogmatisk metod), and partly a comparative method, in conjunction with Swedish and foreign material. The existence of virtual property is based on
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Hedersrelaterat våld och förtryck har fått stor uppmärksamhet i samhällsdebat-ten under 2000-talet. Den ökade uppmärksamheten har resulterat i en rad åt-gärder från staten, däribland kriminaliseringar. För att en ny kriminalisering ska vidtas behöver den kunna rättfärdigas. I statliga utredningar och doktrin framförs kriterier och principer som bör vara uppfyllda för att en kriminali-sering ska vaHonor-related violence and oppression has received a lot of attention in Swe-den during the 2000s. The increased attention has resulted in a number of measures from the state, including criminalization. A new criminalization must be justified in order to be established. State investigations and doctrines set out criteria and principles that should be met for a criminalization to be ac-ceptable. In
