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Background During the last 15 years, high-dose chemotherapy with autologous hematopoietic stem cell transplantation (HSCT) has globally been performed for severe multiple sclerosis (MS). Most patients have been in progressive phase with long disease duration. As a rule, treatment effect has been minor or moderate. Patients Since 2004, we have performed HSCT in nine young patients with "malignant"
The hypoxic zone in the Baltic Sea has increased in area about four times since 1960 and widespread oxygen deficiency has severely reduced macro benthic communities below the halocline in the Baltic Proper and the Gulf of Finland, which in turn has affected food chain dynamics, fish habitats and fisheries in the entire Baltic Sea. The cause of increased hypoxia is believed to be enhanced eutrophic
We propose a universal transformation from a many-boson state to a corresponding many-fermion state in the lowest-Landau-level approximation of rotating many-body systems, inspired by the Laughlin wave function and by the Jain composite-fermion construction. We employ the exact-diagonalization technique for finding the many-body states. The overlap between the transformed boson ground state and th
Objective Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared wi
A generally accepted way of building passive houses has been to have small windows facing north and large windows to the south. This is to minimize losses on the north side while gaining as much solar heat as possible on the south. ln spring 2001, 20 terraced houses were built outside Gothenburg partly in this way. The indoor temperature is kept at a comfortable level by passive methods, using sol
For many patients with von Willebrand disease (VWD), the replacement therapy with von Willebrand factor (VWF)/factor VIII (FVIII) concentrates is the treatment of choice. To evaluate clinical efficacy, safety and tolerability of Wilate, an albumin-free VWF/FVIII concentrate with a ratio of the two haemostatic moieties of approximately 1 to 1, a prospective clinical programme has been designed. The
Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation
Recycling of textile fibers is a mandatory step in the life-cycle of fabrics to avoid incineration or landfilling. After fiber-to-fiber recycling, cellulose fiber saccharification opens the door to the production of biochemical building blocks through microbial fermentation. This study documents for the first time the production of optically pure D-lactic acid (D-LA), one of the precursors of poly
Mer än 10% av Sveriges befolkning lider av någon fobi och detta projekt studerar möjligheten att lindra akrofobi (höjdskräck) med hjälp av virtual reality (VR). Arbetets syfte är därför att undersöka hur man på bästa sätt kan lindra akrofobi med hjälp av VR. Frågeställningarna som skulle besvaras var: ”Kan man med hjälp av enbart visuell och auditiv feedback skapa en trovärdig miljö för att lindraMore than 10% of Sweden's population suffers from some kind of phobia and this project is studying ways to ease acrophobia (fear of heights) with virtual reality (VR). Therefore, the purpose of the work was to investigate how to best ease acrophobia with help of VR. The research questions to be answered were: "Is it possible with just visual and auditory feedback to create a credible envi
En ökad tillgång till och användning av information utmanar både de tekniska system och den lagstiftning som finns idag. Det är därför viktigt att det finns säkra och transparenta digitala tekniker för transaktioner och informationslagring samt lagstiftning som hanterar detta. Genom blockkedjeteknik kan parter registrera och verifiera transaktioner, dokument och avtal med fullständig tillit trots An increased access to and use of information challenges both the technical systems and the legislation there is today. Therefore, it is important that there are secure and transparent digital techniques for transactions and storage of information and a clear legislation on the matter. Through the blockchain technique, parties can register and verify transactions, documents and contracts with full
As cities expand and climate change effects become more intense and frequent, local governance has gained increased attention as capable of implementing the necessary measures for sustainability. One city in Brazil, Jundiaí, has managed to integrate participatory processes in its local planning and has become an example for other cities in Brazil. This city lies between a water reserve and a biolo
Syftet med denna studie var att undersöka förekomsten och graden av alexitymi och dess samband med kvalitet i nära relationer och psykisk ohälsa i en allmänpsykiatrisk population. Studien genomfördes på en allmänpsykiatrisk mottagning för vuxna under två veckors tid med ett konsekutivt urval där patienterna vid ett ordinarie besök ombads besvara ett enkätmaterial. Statistikprogrammet SPSS användesThe aim of this study was to investigate the incidence and degree of alexitymia and its correlation with quality in close relationships and health distress in a general outpatient population. The study was performed in a general outpatient care unit for two weeks with a consecutive selection where the patients, during an ordinary visit, was asked to participate and complete questionnaires assessin
Bakgrund: Konsekvenserna av en förvärvad hjärnskada (FHS) ser olika ut, men innebär ofta en komplex sammansättning av symtom som kräver omfattande, individanpassad, rehabilitering. En brist på interventionsforskning och evidensbaserad kunskap kan ses inom arbetsterapi för barn och unga med FHS. Syfte: Att kartlägga och beskriva arbetsterapeutiska interventioner och dess effekt för barn och unga mBackground: Consequences of an acquired brain injury (ABI) differ and the complex mix of symptoms often requires extensive individualized rehabilitation. There is a lack of intervention research and evidence-based knowledge within occupational therapy for children and adolescents with ABI. Objective: To provide an overview and a description of occupational therapy interventions and their effect o
The now Swedish province of Scania has had a long history of violence and unrest, with several wars being fought on Scanian soil. Such tumultuous times must have impacted the common people and their living conditions, yet bioarchaeological research is lacking for post-medieval Scania and much of Sweden. By analysing a skeletal material from a 16-18th century semi-urban cemetery in Ängelholm, for w
Clean water is an essentiality from both an individual and societal perspective. Legal actions enable the enforcement of the protection that the drinking water resource needs to protect the current but also the future supply of clean and sustainable water. Establishing water protection areas (WPA) is today the legal action that Swedish municipalities or county administration boards have at their d
PURPOSE: To respond to the psychological needs of adolescent and young adult (AYA) cancer survivors, we developed and evaluated a theoretically grounded online intervention to teach adaptive coping skills to promote resilience in early survivorship: 'Recapture Life'. This qualitative study aimed to evaluate the process of implementing Recapture Life into community organisations, after having been
Buildings are responsible for approximately 30% of global energy use, with HVAC systems accounting for 40% of that demand. Among these, data centers have become significant energy consumers, requiring highly efficient and stable cooling solutions. This project aims to explore data-driven control methods to improve the energy efficiency of data center cooling systems as well as reduce the effort an
