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Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly sensitive and easily manageable assay for LMP. LGALS1/galectin-1 and LGALS3/ galectin-3 are best suite
Nodules in the thyroid are frequent. Preoperative investigations including fine-needle cytology and ultrasound cannot in all patients rule out malignancy. Thus, surgical excision for histopathologic examination is often needed. In this narrative review, we examine aspects of the surgical management of indeterminate thyroid nodules, using a comprehensive review of the available literature. The auth
This overview examines available circum-Antarctic glacial history archives on land, related to developments after the Last Glacial Maximum (LGM). It considers the glacial-stratigraphic and morphologic records and also biostratigraphical information from moss banks, lake sediments and penguin rookeries, with some reference to relevant glacial marine records. It is concluded that Holocene environmen
Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. Classical reaction engineering was combined with genetic engineering to improve the production of chiral alcohols and kinetic resolution of racemic ketones with high enantiomer
INTRODUCTION: Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain. The incidence of Merkel cell carcinoma has increased in the past three decades.CASE PRESENTATION: A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three-month history of balance disturbance. M
Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16
Outcrops of the Ordovician System in South Africa are extensive; they cover significant portions of the Northern, Western and Eastern Cape provinces as part of the Cape Fold Belt as well as the KwaZulu-Natal Province as supracrustal cover overlying the Natal sector of the Paleoproterozoic Namaqua-Natal metamorphic province. Within the Cape Fold Belt, Ordovician rocks of the Table Mountain Group (P
When assessing the moisture damage risks of different external wall designs using hygrothermal simulation software, the user of said software can choose between different inputs for the determination of the indoor climate. This paper aims to compare results from field measurements in three Swedish buildings using different standards available in a widely used commercial hygrothermal simulation sof
There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asse
The effect of plant species diversity on productivity and competitive ability was studied in an experiment carried out simultaneously in five European countries: Czech Republic (CZ), the Netherlands (NL), Sweden (SE), Spain (SP), and United Kingdom (UK). The aim was to separate the 'chance' or 'sampling effect' (increasing the number of sown species increases the probability that a species able 't
1 Plant species differ in their capacity to influence soil organic matter, soil nutrient availability and the composition of soil microbial communities. Their influences on soil properties result in net positive or negative feedback effects, which influence plant performance and plant community composition. 2 For two grassland systems, one on a sandy soil in the Netherlands and one on a chalk soi
For the last decades, molecular imprinting is developing intensively, especially in the case of the application of new imprinting techniques. In this work, for the first time, a Pickering emulsion polymerization was used to synthesize the S-naproxen-imprinted polymer spheres following a noncovalent protocol. To enhance the knowledge about imprinting process using mentioned technique, thorough anal
A series of poly(arylene piperidinium)s (PAPipQs) devoid of any alkali-sensitive aryl ether bonds or benzylic sites are prepared and studied as anion exchange membranes (AEMs) for alkaline fuel cells. First, the excellent alkaline stability of the model compound 4,4-diarylpiperidinium is confirmed. Medium molecular weight poly(arylene piperidine)s are then synthesized in polycondensations of N-met
Uppreningsprocessen av monoklonala antikroppar (mAbs) är dyr, speciellt det kromatografisteg där antikropparna separeras från andra protein och celler i lösningen från tidigare steg i processen. Antikropparna separeras från lösningen med hjälp av affinitetskromatografi, där det endast är antikropparna som interagerar med innehåller i kolonnen och stannar kvar, medan resten passerar obehindrat. AntThe purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column
Microsoft Word - Final statement GS Lund.docx Progamme evaluation of Master Programme in Global Studies, Master Programme in Development Studies and Master Programme in Social Studies of Gender: Statement from external expert group Assignment and external expert group The assignment of the external expert group (see composition below) has been to evaluate the Master Programme in Global Studies, Ma
https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2021-09/GS-Statement-expert-group-2021.pdf - 2026-05-14
Brevmall 2019-12-17 Besöksadress Telefon dir Växel E-post Internet Sölvegatan 37 046-222 3782 046-222 0000 Yvonne.Persson@cec.lu.se http://www.miljovetenskap.lu.se Mi l jövetenskapl ig utb i ldn ing Centrum för mi l jö- och k l imatforskn ing Välkommen till kursen MVES03 Ett cirkulärt och biobaserat samhälle VT2020 Vi vill hälsa dig välkommen till kursen Ett cirkulärt och biobaserat samhälle. Vi h
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/valkomstbrev_mves03_vt20.pdf - 2026-05-14
Limiting climate Impact of plastics “Solutions to limit the climate impact of plastics” was the topic of the 2018 Climathon in Lund. The 24 hour hackathon gathered 54 participants and was thereby one of the larger among the 113 Climathons held simultaneous all around the world. Climathon in Lund was organised by a consortia of five very different organisations, Lunds Universitet, Lunds Kommun, Sys
https://www.climate-kic.lu.se/climathon/climathon-lund-2018 - 2026-05-13
From the Management Welcome back to a new year at CEC, where we start 2021 with a new name, a new Director, and a new leadership organisation. Yet, CEC will continue its work with research, education and collaboration, across subject boundaries, to promote sustainable development. The new organisation with a separate Director, Per Persson, and Chair of the Board, Henrik Smith, will strengthen CEC.
https://www.cec.lu.se/staff-pages/staff-newsletters/january-14th-2021 - 2026-05-13
In the broad field of biology, our researchers study everything from small cells to large ecosystems. Research projects include the forces of evolution, unsung heroes of the soil, how animals navigate and seeking answers to the mystery of ageing. Animals with unique abilitiesHow do birds, insects and some other animal groups manage to keep a straight course over long distances? The fascinating abi
https://www.science.lu.se/research/our-research-areas/biology-life-our-planet - 2026-05-13
