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Popular Abstract in Swedish Blodet har en viktig funktion i kroppen. Blodet bildas i den röda benmärgen och består av olika typer av celler med olika specialiserade funktioner, varav många livsnödvändiga. De röda blodkropparna transporterar syre till alla våra kroppsdelar så att våra muskler fungerar och vi orkar gå och springa och så att vår hjärna kan arbeta. De vita blodkropparna hjälper oss atThe t(6;9) translocation is found in a subset of patients with acute myeloid leukemia (AML) and is associated with a poor prognosis. The translocation results in the formation of the DEK-NUP214 fusion protein containing almost the entire nuclear protein DEK and two thirds of the nucleoporin NUP214. The molecular mechanisms behind the leukemic conversion of cells expressing the fusion protein DEK-N

Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe

Popular Abstract in Swedish Immunförsvaret har till uppgift att skydda kroppen mot främmande mikroorganismer såsom bakterier och virus. En rad olika celler, vävnader samt organ samarbetar för att utforma ett väl fungerande immunförsvar. Det är ytterst viktigt att immunförsvaret känner igen kroppsfrämmande ämnen (antigen), som till exempel bakterieceller, men också att det skiljer dessa från kroppsGeneration of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease

Popular Abstract in Swedish Frontotemporal demens är ett sjukdomstillstånd där nervceller i hjärnans pann- (“fronto”) och tinninglober (“temporal”) förtvinar, vilket leder till en tilltagande cellförlust och uttunning av hjärnbarken i dessa områden. Till skillnad från Alzheimers sjukdom, den vanligaste demenssjukdomen, leder frontotemporal demens i första hand inte till försämrat minne och orienteThe present thesis explores alterations in brain morphology in the neurodegenerative disorder of frontotemporal dementia (FTD). With the aim to improve the clinical diagnostics of FTD, we explored the diagnostic potential of measuring morphological alterations in the white matter by diffusion tensor imaging (DTI)- MRI, compared with the more commonly used assessment of grey matter thickness and vo

Background: There are differences in drug use depending on non-medical factors such as age, gender and socioeconomic status. The combined effect of these factors, with adjustment for multimorbidity, is highly relevant to study to ensure equality in drug use. Objectives: 1. To examine drug use related to age, gender, income and education after adjustment for multimorbidity, in an entire adult popul

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Målet med denna avhandling var att undersöka hur cancersjukdomar i barndomen och behandlingen av dessa påverkar olika aspekter av fortplantningsförmågan i vuxen ålder. Glädjande nog har andelen patienter som överlever cancer i barndomen de senaste decennierna ökat stadigt till nivåer som idag ligger på nästan 80%. Ökad överlevnad medfChildhood cancer (CC) survival rate has increased over the last couple of decades, today approaching 80%. Therefore more attention has been paid to late effects. One important issue for CC survivors (CCS) is impaired reproductive function. CC per se and/or its treatment can impair the reproductive ability by affecting sperm production, as well as by damaging sperm DNA. This is a matter of concern,

Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env

Popular Abstract in Swedish Den kroniska inflammation som ses hos personer med inflammatorisk tarmsjukdom är troligen en immunologisk reaktion riktad mot normala tarmbakterier. I denna process har monocyter/makrofager (särskild celltyp av vita blodkroppar) en central betydelse. Det är huvudsakligen makrofager i tarmslemhinnan som styr det immunsvar som utvecklas då tarmfloran kommer i kontakt med Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. This study aimed at exploring the effects and regulation of chronic inflammation in inflammatory

Popular Abstract in Swedish p53 Ñett protein som kan fŒ leukemiceller att bli mera mogna Vid akut leukemi ansamlas omogna blodceller med nedsatt fšrmŒga till utmognad och programmerad celldšd. Detta leder till frŒnvaro av normala blodceller, vilket Šr huvudorsaken till de infektioner och blšdningsrubbningar som utgšr leukemins frŠmsta symptom. Akut leukemi har hittills framfšr allt behandlats medThe terminal differentiation of leukemic cells is closely connected to their death. The concept of differentiation therapy originates from the idea that forced maturation of leukemic cells could induce cell death without the side-effects that are provoked by ordinary chemotherapy. The tumour suppressor protein p53 is a transcription factor, and can induce cell cycle arrest and apoptosis of maligna

CO-HOPE was an inter- and transdisciplinary research project carried out from April 2022 to March 2025. The CO-HOPE consortium consisted of researchers and practitioners in the fields of collaborative housing, architecture, urban planning, geography, social work and health; and country teams were based in Sweden, Austria, France and Spain. Main applicantLund University, SwedenIvette ArroyoPrincipa

https://www.architecture.lth.se/about/subject-areas/housing-development-and-management/collaborative-housing-pandemic-era-co-hope - 2026-05-09

COVID-19: Advice From Our Colleague in China - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluatio

https://rwi.lu.se/blog/advice-from-our-colleague-in-china/ - 2026-05-09

Background The Master’s Thesis Case Study Company is a premium brand automotive OEM. In the Swedish fleet car (or company car) market, the company is lagging behind its main competitors in terms of market share a fact that is not true for several other European markets. Concurrently, the automotive industry is set to go through radical changes the next few years. The speedy development of digitali

Course evaluation for GEON08 2021 report For 2021, it was the ninth time the Master course GEON0B (previously called GEON04) was taught. Nine students took the course this year and eight answered the course evaluation. The statistics for the course are shown below, and in this summary, only general comments are made. All involved teachers and the student representatives have received the full repo

https://www.geology.lu.se/sites/geology.lu.se/files/2021-06/GEON08%2021%20Course%20evaluation%20w%20signatures%20v2.pdf - 2026-05-10

Progamme evaluation of PhD education in Service Studies: Statement from external expert group Page 1 of 23 STATEMENT FROM EXTERNAL EXPERT GROUP Reg. No. STYR 2023/22 2023-11-03 Evaluation report for the Department of Human Geography: bachelor and master studies in Human Geography and Urban planning Assignment and composition of the external expert group The expert group consists of two (originally

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2024-05/Statement-expert-group_HUGE_final.pdf - 2026-05-10

Visit us | Vattenhallen Science Center Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifia

https://www.vattenhallen.lu.se/english/visit/ - 2026-05-09

How do care seekers navigate through healthcare services and make choices about where to access medicines? Rui Liu took an interest in the field of substandard and falsified medicine when she began with her doctoral studies. She had the ambition to focus on the grey zones and bring awareness of what counts as legal, ethical and moral. With a bachelor’s degree in applied linguistics and two master’

https://www.ses.lu.se/en/research/doctoral-studies/meet-our-doctoral-students/rui-liu-im-looking-doctor-patient-relationships-care-practices-and-particularly-medicine-access - 2026-05-09

“Well; if they are not going to sign a peace treaty, I don’t think we are interested.”Det er i ugen inden åbningen af den nye Øresundsbro, 1. juli, 2000. Personen i den anden ende af røret er en international redaktør for ”The NewsHour with Jim Lehrer” – måske det nyhedsprogram i USA der minder mest om europæisk dybdeborende TV-journalistik. Programmet sendes over hele USA mandag-fredag gennem et

https://www.cors.lu.se/publikationer/gastkronikor-0/regionen-som-forsvandt - 2026-05-09

Solid Waste Management RECOMMENDATIONS FOR KISUMU, KENYA Mistra Urban Futures Policy Brief 2019:1 Kisumu City generates approximately 400 tonnes of solid waste per day, 20%- 25% of which is collected to the open dump site. Of the total municipal solid waste that is collected, 65% is organic and another 27% is recyclable (County of Kisumu, 2015). The collection and handling of municipal solid waste

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/policy-brief-2019-final-draft_barry_ness.pdf - 2026-05-10

COSB40 Literature list 2025 Literature list COSB40 2025 The literature in ques.on is available as e-resources though LUBsearch, or online via links in literature list. NEW FOR 2025 Curato, Nicole. "Flir.ng with authoritarian fantasies? Rodrigo Duterte and the new terms of Philippine populism." Journal of Contemporary Asia 47.1 (2017): 142-153. Pages to read for the students: 12 p. Curato, Nicole,

https://www.ace.lu.se/sites/ace.lu.se/files/2024-12/COSB40%20Literature%20list%202025.pdf - 2026-05-10

Questions Can the model performance of the landscape reconstruction algorithm (LRA) for small forest hollows be validated through comparison to inventory-based vegetation reconstructions from the last 150yrs? Does the application of LRA and the comparison to historical data enhance interpretation of the pollen record? Location Denmark. The Gribskov-Ostrup small forest hollow (56 degrees N, 12 degr