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The optical klystron installed on the Elettra storage-ring is normally used as interaction region for an oscillator free-electron laser, but, removing the optical cavity and using an external seed laser, one obtains an effective scheme for single-pass harmonic generation. In this configuration the high-power external laser is synchronized with the electron beam entering the first undulator of the
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
Kära medlemmar av Nordic Network for Narratives in Medicine, Här är nyheter och aktiviteter som kan vara intresse! 1. Syddansk universitet arrangerar en digital konferens, Uses of Literature den 3–5 november, som avslutar Rita Felskis Niels Bohr-professur vid universitetet. Hela konferensen kan vara av intresse, och den innehåller också en stream om narrativ medicin. Konferensen är helt online och
Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
IntroductionRecreational hunting in Sweden can be depicted as being embedded in two different but overlapping cultural and socio-economic contexts. One is the traditional non-commercial and stewardship-oriented form hunting, in Swedish called ‘allmoge’ hunting. It is characterised by a democratic hunting tradition where the local hunting team is ascribed a main role in wildlife management. These tThe paper is based on a study of hunting tourism enterprising in Sweden. The study examines how hunting tourism businesses in Sweden navigate in a complex social, economic and moral environment. The aim of the present paper is to identify how tensions between a market- oriented value sphere and a value sphere based on friendship- and community reciprocity are played out in hunting tourism entrepre
Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces
EduLab lägesrapport 10 juni 2024 1 Aktivitetsrapport juni 2024 10/6, 2024 2 Kort överblick för upptaget folk Rapporten beskriver EduLabs verksamhet 2022-2024, baserat på fyra huvudsakliga presentationsspår. Till huvuddokumentet fogats appendix som innehåller ett antal av EduLabs tematiska briefingrapporter. Mikael Sundström, EduLab, Lund, Juni, 2024. Kursutveckling poänggivande kurser EduLab har
