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In recent decades, working with computers has evolved from a specialized area to a requirement at most workplaces. Information systems also change regularly and employees have to adapt to new computer systems. However all individuals do not like computer work and the concept of computer anxiety describes human attitudes to computers. This study examined how computer anxiety is influenced by an inf

The purpose of this work is to investigate the negative legal force of decisions under immigration law compared to under administrative law in general, with the exception of environmental protection law, public purchasing law and certain local government laws. The comparison refers to the underlying ideas, presence, factual extent and protection of the factual extent. Negative legal force of the

In this work company announcements of blockchain name changes are empirically analysed to obtain a sense of how markets value the blockchain technology. This “blockchain effect” is analysed using an event study in order to calculate cumulative abnormal returns for multiple event windows. The “blockchain effect” generates cumulative average abnormal return of 58 percent for the five days surroundin

This paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis indThis paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis ind

Background/Aims: Inguinal incisions are a common route of access in vascular surgery. Due to anatomical challenges and a diverse bacterial flora in this area, surgical site infections (SSI) represent a common, debilitating and sometimes life-threatening complication. The INVIPS-Trial evaluates the role of Negative Pressure Wound Therapy (NPWT) on closed inguinal incisions in elective vascular surg

Background and aims: Although aortic stenosis is the most common valvular heart disease requiring intervention in Europe, the role that diet plays in development of the disease is largely unknown. The pathophysiology of aortic stenosis is however similar to other cardiovascular diseases that fiber intake has been associated with. The aim of this study was consequently to investigate the associatio

Radiopharmaceutical therapy is used to treat cancers and other diseases with radiolabeledpharmaceuticals. The treatment targets specific cells, and the emitted ionizing radiation cause cytotoxicdamage. Dosimetry is performed to estimate the absorbed dose from the energy deposited in the body.This requires measurement of the activity in vivo and knowledge of the retention time of the activity in tu Radiopharmaceutical therapy is used to treat cancers and other diseases with radiolabeled pharmaceuticals. The treatment targets specific cells, and the emitted ionizing radiation cause cytotoxic damage. Dosimetry is performed to estimate the absorbed dose from the energy deposited in the body. This requires measurement of the activity in vivo and knowledge of the retention time of the activity i

BACKGROUND: To inform future preventive measures including repeated vaccinations, we have searched for a clinically useful immune correlate of protection against fatal COVID-19 among nursing homes residents.METHODS: We performed repeated capillary blood sampling with analysis of S-binding IgG in an open cohort of nursing home residents in Sweden. We analyzed immunological and registry data from 16

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon resp

Matola, a major Mozambican city, has witnessed flooding, mainly caused by rainfall. The study aims to produce flood-hazard and flood-risk maps for Matola using the hydrological model TFM-DYN. For 2000, 2020, and 2040, the modeled extent of medium-risk area is 50.6 km2 (13.7%), 44.8 km2 (12.2%), and 39.0 km2 (10.6%) and of high-risk area is 43.3 km2 (11.8%), 31.8 km2 (8.6%), and 28.9 km2 (7.8%), re

The COVID-19 crisis intensified decade-long debates on the interaction between intellectual property rights (IPRs), competition law and access to affordable life-saving treatments and vaccines. Compulsory licensing of patented medicines is a tried-and-tested method to expand access, particularly in a situation of “national emergency or other circumstances of extreme urgency” within the meaning of

BACKGROUND: Child stunting is a significant challenge for most districts in Rwanda and much of sub-Saharan Africa and persists despite multisectoral efforts. There is a notable lack of population-based studies examining the correlation between violence against women and child stunting in Rwanda.OBJECTIVE: We aimed to investigate the association between Rwandan women's exposure to intimate partner

Satellite imagery is a potent tool for estimating human wealth and poverty, especially in regions lacking reliable data. This study compares a range of poverty estimation approaches from satellite images, spanning from expert-based to fully machine learning-based methodologies. Human experts ranked clusters from the Tanzania DHS survey using high-resolution satellite images. Then expert-defined fe

Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypox

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

Considering that the number of wheelchair users is on the rise at the global level due to population aging, it is crucial to secure their rights to have adequate access to healthcare services. Spatial accessibility to healthcare services has been well recognized to influence people's health. However, research on healthcare accessibility of wheelchair users is scarce. This study proposes a barrier-