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Treatment resistant depression (TRD) and suicidal behavior are among the most important public health problems and are commonly associated with significant disability and psychosocial impairment. Although there have been recent advances in identifying neurobiological correlates of these complex conditions, their pathophysiology still remains unclear. Although the recent advances concerning the neu

Introduction: Under-dosing is a recognized problem with current nicotine replacement therapy (NRT). Therefore, a new 6mg nicotine gum has been developed. To compare the nicotine uptake from the 6mg gum versus currently available NRT products, two pharmacokinetic studies were performed.Methods: In one randomized crossover study, 44 healthy adult smokers received single doses of 6, 4, and 2mg nicoti

This paper presents an acoustofluidic chip for the sorting of bacteria from protozoa in water using standing acoustic waves. The size-based acoustophoretic sorting method provides a means for sample pre-concentration, which is vital for real-time, on-site monitoring of drinking water quality and preventing outbreak of waterborne diseases. In practice, high throughput and high recovery pre-concentr

Abstract in UndeterminedSometimes energy security is used as an advocacy for renewable energy systems. Although renewable energy systems can surely have such characteristics they will not per se solve all types of security problems, and new problems will most certainly arise. In this paper, energy security aspects of renewable energy systems are analysed taking the starting point in a broad typolo

Kameraövervakning utgör en pågående trend i kommuners och privatpersoners kamp mot brottslighet. Föremålet för denna rapport är ett särskilt fall som sedan april 2004 ansluter till denna trend: övervakningen av parkeringsplatsen på Kasernplan i centrala Landskrona. Rapporten utgår från statistik, medierapportering, enkätundersökningar samt etnografiskt material (intervjuer och fältanteckningar)

We demonstrate proof of principle of an efficient and simple method combining sample preparation and stretching of DNA in a single device that can be used as basis for an integrated portable system for optical DNA mapping. An important bottleneck for DNA mapping, as well as for other methods, is the isolation of long DNA molecules from a background of contaminants such as shorter DNA fragments, dy

We present the first one-step acoustic separation of high quality plasma and mononuclear cells (MNCs) from undiluted human whole blood. This enables centrifugation-free integration in analytical instrumentation.

Implementing electrically connected metal-coated posts in a Deterministic Lateral Displacement (DLD) device and applying electric fields, we use electrokinetics to achieve tunable particle separations and to trap and manipulate DNA. The strength of DLD stems from its typically binary behavior. Particles move in one out of two trajectories based on their effective size. For particles that are close

We developed the AcouWash (Figures 1 and 2), a benchtop instrument for flow-through cell and particle separation by acoustophoresis. Building on previous research [1-4] AcouWash can re-suspend cells in new medium, separate cells based on size or acoustic properties, or enrich cells, Figure 3. We present our initial evaluation of AcouWash regarding size-based separation of particles, cell washing,

We have developed an assay, based on nanofluidic channels and fluorescence microscopy, for optical mapping of DNA based on competitive binding between two molecules - one fluorescent and one sequence selective. From the experimental data we can extract binding constants for the two competing DNA binders, which may be subsequently used to calculate a theoretical reference map of any DNA with known

In this work we present an integrated system for whole chromosome analysis of single bacterium. Using whole genome barcoding techniques, which offer direct and rapid microscopic visualization of the entire genome in one field-of-view, we aim to rapidly identify individual bacterium. We are developing our device to achieve the crucial, and difficult process of isolating a bacterium, removing the DN

Enligt författarnas mångåriga erfarenhet från kustprojekt runt om i Sverige föreligger ett stort behov av en förbättrad terminologi på svenska vad gäller ingenjörsmässiga frågeställningar och planering av kustområden.Föreliggande artikel presenterar således en engelsk-svensk ordlista, inklusive förklarande kommentarer, med syfte att klargöra en lång rad ord och uttryck. Denna finns också att tillg

The paper reviews a number of cellular neural network implementations on a field-programmable gate-array. It illustrates experimentally, how these implementations can be used to measure from images or to create dynamic, autonomous processes that facilitate measurements within topographic maps. Applications range from image understanding to robot navigation