Filtyp
Context. Using emission lines from metals, we investigate the three-dimensional distribution of temperature and chemistry in ultra-hot Jupiters. Aims. Existing observations of WASP-121 b have suggested an underabundance of titanium and titanium oxide in its terminator region. In this study, we aim to determine whether this depletion is global by investigating the dayside emission spectrum. Methods
The skin microbiome undergoes dynamic changes during different phases of wound healing, however the role of bacteria in the wound healing process remains poorly described. In this study, we aimed to determine how wound bacteria develop over time in epidermal wounds, and how they interact with inflammatory processes during wound healing. To this end, we analyzed wound fluid and swab samples collect
BACKGROUND: In patients with a degenerative tear of the medial meniscus, recent meta-analyses and systematic reviews have shown no treatment benefit of arthroscopic partial meniscectomy (APM) over conservative treatment or placebo surgery. Yet, advocates of APM still argue that APM is cost effective. Giving advocates of APM their due, we note that there is evidence from the treatment of other musc
As the impact of climate change intensifies, there is an urge to adapt Swedish residential buildings with a special focus on improving their energy efficiency and resilience. In this study, adaptive strategies through Artificial Intelligence and Reinforcement Learning will be provided for the energy management of different Swedish residential buildings. The aim will be the optimization of energy u
Trots att miljö- och produktionsmål formellt varit jämställda i skogspolitiken under de senaste decennierna, är förlust av biologisk mångfald ett fortsatt problem. Inom skogspolitiken i Sverige och Finland har strategier för ökat skydd av biologisk mångfald framhållit frivillighet, som certifiering av skogsbruk och frivilliga avsättningar mot kompensation. Det saknas dock kunskap om hur resultatenDespite decades of claimed ambitions to increase environmental consideration in forest policy, biodiversity loss in boreal forests continues. As the pressure on forest biodiversity intensifies, due to land use competition, shifting societal demands, and climate change, it is crucial to address the shortfall of biodiversity policies in reaching their intended outcomes. Voluntary policy instruments
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Den här avhandlingen handlar om förbättringar aven process för att producera sk. kirala aminer -en typ av molekyler som ingår bl.a. i många läkemedel. Kirala molekyler är de som finns i två former, sk. enantiomerer, som är varandras spegelbild. Trots sina kemiska och fYsikaliska likheter kan de ha mycket olika biologisk effekt. Ett välThe industrial use of biocatalysts is increasingly important in the production of e.g. pharmaceuticals, chemicals, fuels and foodstuffs. A successful biocatalytic process is dependent on many factors, such as the biocatalyst properties, the nature of the reaction, reactor type and downstream processing. This work is focused on two important issues: Immobilization of the biocatalyst and in situ pro
Cancer cells facilitate growth and metastasis by using multiple signals from the cancer-associated microenvironment. However, it remains poorly understood whether prostate cancer (PCa) cells may recruit and utilize bone marrow cells for their growth and survival. Furthermore, the regulatory mechanisms underlying interactions between PCa cells and bone marrow cells are obscure. In this study, we is
Långvarig smärta är ett vanligt förekommande och tärande tillstånd som är bland de mest kostsamma hälsoproblemen för både individen och samhället som helhet. Kognitiv beteendeterapi (KBT) är den mest spridda psykologiska behandlingen för långvarig smärta. Även om metoden är evidensbaserad och rekommenderad ger den relativt blygsamma förbättringar för smärtrelaterad funktion och medföljande emotionChronic pain is a commonly occurring and debilitating condition, and among the costliest health problems for both the individual and society at large. Cognitive behavioral therapy (CBT) is the most widely-disseminated psychological treatment for chronic pain. Even though it is recommended and evidence-based, it yields quite modest improvements in pain-related functioning and accompanying symptoms
Timetables are important for train punctuality. However, relatively little attention has been paid to the people who plan the timetables: the research has instead been more centred on how to improve timetables through simulation, optimisation, and data analysis techniques. In this study, we present an overview of the state of practice and the state of the art in timetable planning by studying the
European countries have been receiving refugee children for decades with a recent peak in 2015/2016 (Crul 2017). Although the number of refugees currently arriving in Europe must be seen in proportion to the much higher percentage of refugees that remain in states outside European borders (Dryden-Peterson 2016), the inclusion of refugee children is perceived as a major challenge by policy makers a
The traditional representation of urban property as a technical exercise of market analysis, valuation and investment appraisal fails to link urban property development to the general notions of sustainable development and thus the connection to environmental, economic and social aspects of sustainable urban development. Knowledge of the social processes in the production and use of the built envi
This thesis is concerned with the nature of information processing in the nervous system. This issue has been investigated with animal experiments, using male Sprague–Dawley rats, and simulated touch generated by an artificial fingertip with neuromorphic tactile sensors. The processing of the tactile input from the artificial touch system has been analyzed in light of two opposing theories on info
Background: Choroid plexus (CP) supports the entry of monocyte-derived macrophages (MDMs) to the central nervous system in animal models of traumatic brain injury, spinal cord injury, and Alzheimer's disease. Whether the CP is involved in the recruitment of MDMs to the injured brain after ischemic stroke is unknown. Methods: Adult male C57BL/6 mice were subjected to focal cortical ischemia by perm
Accumulation of damaged or misfolded proteins resulted from oxidative protein modification induces endoplasmic reticulum (ER) stress by activating the pathways of unfolded protein response. In pathologic hemolytic conditions, extracellular free hemoglobin is submitted to rapid oxidation causing heme release. Resident cells of atherosclerotic lesions, after intraplaque hemorrhage, are exposed to he
BACKGROUND: The general population is ubiquitously exposed to the toxic metal cadmium through the diet and smoking. Cadmium exposure is associated with increased morbidity and mortality in myocardial infarction and stroke. Atherosclerosis is the main underlying mechanism of myocardial infarction. However, associations between cadmium and coronary artery atherosclerosis have not been examined. OBJE
Can Salvator Mundi and Zlatan make Built Cultural Heritage resilient? The new role of built cultural heritage (BCH), as an economic asset for development strategies and the widened definition as a concept-, explains today’s affluence of sites. These can only be guaranteed with sufficient heritage funding. Financers’ inducement to fund depends on that heritage’s current value estimation and only hi
Migraine is a highly debilitating neurological disorder that affects approximately 15% of the global population. It is most commonly associated with severe headaches that can leave sufferers bedridden, but its impact extends beyond the attacks themselves. The disease presents in various forms, ranging from sporadic attacks to regular ones following the female hormone cycle, and chronic migraine, w
Den 6 juli 2023 tillsattes en särskild utredare med uppdraget att ”överväga och föreslå ändringar av den straffrättsliga särbehandlingen av unga lagöverträdare”. Som en del av detta skulle möjligheten till en sänkt straffbarhetsålder undersökas. I slutbetänkandet som presenterades i januari 2025, föreslogs en differentierad sänkning av straffbarhetsåldern till 14 år. I den efterföljande lagrådsremOn July 6, 2023, an inquiry chair was appointed with the mandate to “consider and propose changes to the special treatment of young offenders under criminal law”. The possibility of lowering the age of criminal responsibility was to be examined. In the final report presented in January 2025, a reduction of the age of criminal responsibility to 14 years was proposed. The subsequent referral to the
This thesis investigates the application of Artificial Intelligence (AI) and Machine Learning (ML) methods to improve carbon footprint estimation for Integrated Circuit (IC) components in automotive Cost Engineering (CE). The work addresses challenges faced by electrical cost engineers at Volvo Cars: the manual, time-consuming process of collecting component specifications, and estimating Carbon D
