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Background and aims: Active aging is the process through which people strive to maintain wellbeing when growing old. Addressing the lack of research on active aging in the context of housing, the aim was to describe active aging among people aged 55 and older considering relocation and investigate whether perceived housing moderates the relationship between functional limitations and active aging.
Enzymes, as efficient and environmentally friendly catalysts, have gainedsignificant scientific and industrial attention for their mild operating conditions,high substrate selectivity and reusability when immobilized. Among them, lipasesdominate the global industrial enzyme market, catalyzing various reactions with afocus on substrate specificity and selectivity. This thesis investigates theoptimi
Purpose: To investigate factors guiding follow-up imaging after hospital discharge in atraumatic intracerebral hemorrhage (ICH) across large European academic centers and compare decision-making patterns using a standardized approach. Methods: Expert neuroradiologists from nine European centers in eight countries detailed their follow-up algorithms for deep and lobar ICH, specifying (1) patient-re
Context. The nuclear stellar disc (NSD) of the Milky Way is a dense, rotating stellar system in the central ~200 pc. The NSD is thought to be primarily fuelled by bar-driven gas inflows from the inner Galactic disc. Aims. As part of the LEGARE project, we aim to construct the first chemical-evolution models for the NSD using a Bayesian approach tailored to reproducing the observed metallicity-dist
Purpose. Continuous minor steps of improvement in the management of breast cancer have resulted in decreased mortality rates during the last decades. The aim of this study was to compare the clinical outcome of patients with stage I breast cancer diagnosed during two time periods that differed with respect to adjuvant systemic therapy. Material and methods. The studied population consisted of all
The healthcare systems of today are facing large challenges, with increasing amounts of patients and overworked hospital staff. Prostate cancer and Alzheimer’s disease are two of the most prevalent diseases, with incidence numbers expected to rise over the coming decade. Medical imaging plays a central role in current diagnostic procedures for these diseases, enabling the potential use of machine-
Niacinamide (NIA) is a widely used skincare ingredient with established benefits for skin barrier support, inflammation reduction, and dermal health. However, the mechanisms governing its transdermal delivery remain insufficiently understood, particularly regarding how formulation pH influences its permeation through the stratum corneum (SC). This study investigates how donor phase pH (5.0 vs. 7.4
The rapid growth in hedge funds has triggered an international debate on the risks involved with their operations and potential negative effects on the financial system. The rise and fall of Long Term Capital Management - which prompted the US Federal Reserve to engineer a bail-out - still haunts the sector 10 years on. Simultaneously we have to admit that markets and investors benefit from a wide
Background: People with intellectual disabilities (ID) may be at higher risk of psychiatric disorders than the general population. However, few studies investigate the role of demographic factors.Methods: This register-based study includes all people living in Skåne, Sweden, on January 1st, 2014. The ID cohort comprises those who received support and service for people with functional impairments
While numerous membrane-bound complement inhibitors protect the body's cells from innate immunity's autoaggression, soluble inhibitors like complement factor I (FI) are rarely produced outside the liver. Previously, we reported the expression of FI in non-small cell lung cancer (NSCLC) cell lines. Now, we assessed the content of FI in cancer biopsies from lung cancer patients and associated the re
Background. The links between chronic kidney disease (CKD) and the high burden of cardiovascular disease remain unclear. We aimed to explore the association between selected inflammatory and angiogenic biomarkers, kidney function and long-term outcome in patients with an acute coronary syndrome (ACS) and to test the hypothesis that CKD status modifies this association. Methods. A total of 1293 ACS
Lignin is the second most abundant biopolymer on Earth after cellulose, found in virtually all plantswhere it is responsible for rigidity, hydrophobicity and mineral transport. For a long time, it has been considereda waste in the paper production process and incinerated for its energy content. However, with the depletion ofcrude oil reserves, it has been found to have a large potential to become
The aim of this WaterWarmth project Work Package 6.1 report is to present a number of relevant frameworks available to analyse and/or assess the governance of current heating systems and future energy system innovation, in particular with a focus on aquathermal energy (AE) systems. At the basis of the report was a broad survey of the academic and other literature by project researchers on ways to
Treatment with the anti-angiogenic drug bevacizumab in addition to chemotherapy has shown efficacy for breast cancer in some clinical trials, but better biomarkers are needed to optimally select patients for treatment. Here, we present an omics approach where DNA methylation profiles are integrated with gene expression and results from proteomic data in breast cancer patients to predict response t
A larger amount of older people need to participate in working life due to the global demographic change. It is the employer, through the manager, who enables employees to have access to measures in the workplace that facilitate and enable a sustainable extended working life. The aim of this study was to evaluate work life factors associated with managers believing their employees can work versus
Rare disease data is often fragmented within multiple heterogeneous siloed regional disease registries, each containing a small number of cases. These data are particularly sensitive, as low subject counts make the identification of patients more likely, meaning registries are not inclined to share subject level data outside their registries. At the same time access to multiple rare disease datase
Ring signatures enable a signer to sign a message on behalf of a group anonymously, without revealing her identity. Similarly, threshold ring signatures allow several signers to sign the same message on behalf of a group; while the combined signature reveals that some threshold t of the group members signed the message, it does not leak anything else about the signers’ identities. Anonymity is a c
Second language (L2) learners experience challenges when word meanings differ across L1 and L2, and often display crosslinguistic influence in speech production. In contrast, studies of online comprehension show more mixed results. Therefore, this study explored how L2 learners process fine-grained L2 verb semantics in the domain of caused motion (placement), and specifically the impact of having
BACKGROUND: Transportation noise is increasingly acknowledged as a cardiovascular risk factor, but the evidence base for an association with stroke is sparse. OBJECTIVE: We aimed to investigate the association between transportation noise and stroke incidence in a large Scandinavian population. METHODS: We harmonized and pooled data from nine Scandinavian cohorts (seven Swedish, two Danish), total
In the beginning of the COVID-19 pandemic, several super spreader events occurred during singing in choirs, which lead to an increased attention to airborne transmission of SARS-CoV-2, the virus causing COVID-19. Since then, aerosol generation from singing has been studied in more detail, however, only from healthy subjects. In this study, we collected aerosol particles in the exhaled breath of 40
