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Loss of forest naturalness challenges the maintenance of green infrastructure (GI) for biodiversity conservation and delivery of diverse ecosystem services. Using the Convention on Biological Diversity's Aichi target #11 with its quantitative and qualitative criteria as a normative model, we aim at supporting landscape planning through a pioneering assessment of the extent to which existing amount
ObjectiveTo examine etiologic stroke subtypes and vascular risk factor profiles and their association with white matter hyperintensity (WMH) burden in patients hospitalized for acute ischemic stroke (AIS).MethodsFor the MRI Genetics Interface Exploration (MRI-GENIE) study, we systematically assembled brain imaging and phenotypic data for 3,301 patients with AIS. All cases underwent standardized we
Alternative ways for increased appetite control are today widely sought for due to the growing global health issues connected to obesity. In in vivo studies, oat has been proven an attractive candidate for inducing satiety. Oat is rich in polar lipids, of which the galactolipids are especially interesting, and a hypothesis is that these lipids play an important role for the ileal brake mechanism.
We used PCR and DNA sequencing to screen for haemosporidian parasites (Haemoproteus and Plasmodium) in 2,488 individual birds from 104 species and 22 families, primarily understory suboscine passerines, captured in a lowland Amazonian forest in Ecuador as a first major step to understanding the transmission dynamics of this cosmopolitan group of parasites in this region. To assess diversity of avi
Early genome-wide association (GWA) studies on Parkinson's disease (PD) have not been able to yield conclusive, replicable signals of association, perhaps due to limited sample size. We aimed to investigate whether association signals derived from the meta-analysis of the first two GWA investigations might be replicable in different populations. We examined six single-nucleotide polymorphisms (SNP
This dissertation presents cryptanalysis of several symmetric lightweight primitives, both stream ciphers and block ciphers. Further, some aspects of authentication in combination with a keystream generator is investigated, and a new member of the Grain family of stream ciphers, Grain-128a, with built-in support for authentication is presented. The first contribution is an investigation of how au
Asymptotics plays a crucial role in statistics. The theory of asymptotic consistency of Bayesian nonparametric procedures has been developed by many authors, including Schwartz (1965), Barron, Schervish and Wasserman (1999), Ghosal, Ghosh and Ramamoorthi (1999), Ghosal, Ghosh and van der Vaart (2000), Shen and Wasserman (2001), Walker and Hjort (2001), Walker (2004), Ghosal and van der Vaart (2007
There is a global concern about the decline of wild pollinators and the ecosystem services they provide. Although land-use change is a major threat to biodiversity, it is still poorly understood how land-use heterogeneity (or land-use structure) impacts pollinator communities and entomophilous crop production. Based on a literature review, we performed a meta-analysis to (1) assess how landscape s
With the ever growing requirement for higher data rates, terminals supporting multiple-input multiple-output (MIMO) technologies (or MIMO terminals) are being developed for the beyond-3G wireless communication systems such as HSPA and LTE. To ensure that the terminals are capable of delivering the promises of MIMO technology, test systems for the performance evaluation of MIMO devices are needed.
Molecular subtyping has been a major focus of bladder cancer research over the past decade. Despite many promising associations with clinical outcomes and treatment response, its clinical impact has yet to be defined. As part of the 2022 International Society of Urological Pathology Conference on Bladder Cancer, we reviewed the current state of the science for bladder cancer molecular subtyping. O
Aims: Social science literature suggests that unlimited trust in others may lead to adverse outcomes, and that moderate trust may be more optimal in social interactions. The aim was to analyze associations between generalized trust in other people and all-cause mortality using a four-alternative generalized trust item that includes moderate trust. Study design: Prospective cohort study. Methods: T
Avhandlingen undersöker föreningar i Sverige som organiserar öppna verkstäder. Öppna verkstäder, vilka också kallas för makerspaces, är platser som möjliggör skapande. Verktyg, maskiner och kunskap är delade mellan användarna. Syftet med avhandlingen är att undersöka hur föreningar organiserar sina delade verkstäder, vilka svårigheter föreningarna möter samt vilka implikationer detta har för den bAlternative building as an interstitial mode of transformation plays a central role in the discussion of strategies for degrowth. In this debate the questions of how alternative projects can be scaled up and how degrowth politics can gain broad societal support have been identified as crucial. In this context open workshops – grassroots infrastructures for creative activities, such as repair, upcy
Sexual conflict frequently gives rise to adaptations that increase male reproductive success at the expense of harming females (“male harm”) and decreasing population growth. Studying the ecology of male harm is paramount to understand how sexual conflict unfolds in nature, and its consequences for populations viability. Here, we used seed beetles (Callosobruchus maculatus), a species where males
Many animals undergo irreversible ontogenetic color changes (OCCs), yet these changes are often overlooked despite their potential ethological relevance. The problem is compounded when OCCs involve wavelengths invisible to humans. Wall lizards can perceive ultraviolet (UV) light, and their conspicuous ventral and ventrolateral coloration—including UV-reflecting patched—likely serves social communi
Amyloid-β (Aβ) is hypothesized to facilitate the spread of tau pathology beyond the medial temporal lobe. However, there is evidence that, independently of Aβ, age-related tau pathology might be present outside of the medial temporal lobe. We therefore aimed to study age-related Aβ-independent tau deposition outside the medial temporal lobe in two large cohorts and to investigate potential downstr
Human activities in coastal areas have intensified over the last 200 years, impacting also high-latitude regions such as the Baltic Sea. Benthic foraminifera, protists often with calcite shells (tests), are typically well preserved in marine sediments and known to record past bottom-water conditions. Morphological analyses of marine shells acquired by microcomputed tomography (µCT) have made signi
Background: Huntington’s disease (HD) is a motor and cognitive neurodegenerative disorder due to prominent loss of striatal medium spiny neurons (MSNs). Cell replacement using human embryonic stem cells (hESCs) derivatives may offer new therapeutic opportunities to replace degenerated neurons and repair damaged circuits. Methods: With the aim to develop effective cell replacement for HD, we assess
Background: Induced hypothermia post-cardiac arrest is neuroprotective in animal experiments, but few high-quality studies have been performed in larger animals with human-like brains. The neuroprotective effect of postischemic hypothermia has recently been questioned in human trials. Our aim is to investigate whether hypothermia post-cardiac arrest confers a benefit compared to normothermia in la
Objective To elucidate experiences and coping strategies among adults in the surveillance of indeterminate pulmonary nodules detected with CT in the population-based Swedish CardioPulmonary bioImage Study (SCAPIS).Design A qualitative study of conventional content analysis.Settings The study was conducted at a university hospital in a southern region of Sweden. The SCAPIS setting is similar to the
ObjectivesThis study aimed to develop and externally validate a model for predicting insufficient future liver remnant (FLR) hypertrophy after portal vein embolization (PVE) based on clinical factors and radiomics of pretreatment computed tomography (CT)Patients and methodsClinical information and CT scans of 241 consecutive patients from three Swedish centers were retrospectively collected. One c
