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Background: We investigated the impact of time to adjuvant chemotherapy (AC) on survival after surgical resection (<8 weeks or 8–16 weeks) for patients with non-small cell lung cancer (NSCLC) by applying a target-trial emulation. Material and Methods: We used Swedish population-based healthcare registries to emulate a hypothetical target trial, with treatment arms of ‘initiate AC <8 weeks postoper
This study investigates the requirements for estimating CO2 emissions at the country scale using observational data from the Integrated Carbon Observation System (ICOS) atmosphere network, taking Italy as a case study. In particular, we explore the potential expansion of Italy’s current atmospheric ICOS network by identifying additional existing and future stations that would most effectively impr
Social workers in Swedish child welfare operate within a context where children’s right to express their views is legally regulated, while professional decision-making often takes place in complex situations involving different perspectives and interests. This study aimed to explore how social workers describe their use of professional discretion in cases where children’s and parents’ wishes do no
Ett problem med parkeringsapplikationer är att användare ofta glömmer att avsluta aktiva parkeringssessioner, vilket leder till överbetalning. Denna uppsats designar och utvärderar automatisk avslutning av parkering på ett sätt som minskar överbetalning samtidigt som användarnas tillit och kontroll bevaras, samt utvärderar resultatet. Projektet resulterade i en testapplikation för iOS med en automA problem with parking applications is that users often forget to end active parking sessions, which leads to overpayment. This thesis designs and implements automatic parking termination in a way that reduces overpayment, while preserving user trust and control, as well as evaluating the results. The project resulted in an iOS test application with an automatic termination feature called AutoStop
Kursguide - Course Syllabus • • • • • • • Fastställande Kursplanen är fastställd av Utbildningsnämnden för Musiklärarutbildningen 2019-03- 12 att gälla från och med 2019-09-02, vårterminen 2020. Allmänna uppgifter Kurs inom kulturskolepedagogutbildningen (LGKSP) Undervisningsspråk: Svenska Kursens mål Efter avslutad kurs skall den studerande reflektera och resonera kring planering och genomförande
https://www.mhm.lu.se/sites/mhm.lu.se/files/kursplaner_t2.pdf - 2026-07-06
Kursguide - Course Syllabus • • • • • • • Fastställande Kursplanen är fastställd av Utbildningsnämnden för Musiklärarutbildningen 2019-03- 12 att gälla från och med 2019-09-02, vårterminen 2020. Allmänna uppgifter Kurs inom kulturskolepedagogutbildningen (LGKSP) Undervisningsspråk: Svenska Kursens mål Efter avslutad kurs skall den studerande reflektera och resonera kring planering och genomförande
https://www.mhm.lu.se/sites/mhm.lu.se/files/kursplaner_t2_kulturskolepedagog90hp.pdf - 2026-07-06
Background: Despite smoking and risky alcohol drinking being modifiable risk factors for cancer as well as postoperative complications, perioperative cessation counselling is often ignored. Little is known about how cancer patients experience smoking and alcohol interventions in relation to surgery. Therefore the aim of this study was to explore how bladder cancer patients experience a perioperati
The study of pragmatic markers attracts many scholars within the field of pragmatics, in particular in the area of radical pragmatics. Pragmatic markers are often perceived by speakers as having vague meanings that are hard to pin down in words. A pragmatic marker marker also often seem to contribute in different ways to the explicit or implicit message that the speaker wants to convey depending o
Background: Childhood obesity is an urgent public health concern, and there's a need for long-term, high-quality, primary prevention trials targeting parents of young children. The aim of the current study was to evaluate the long-term effect of a parental support program based on motivational interviewing (MI). Methods: A cluster randomized controlled trial was carried out in eight Swedish counti
Objective: Atypical responses to sensory stimuli are common features of autism spectrum disorders (ASD). Consequently, atypical sensory reactivity (SR) is now a diagnostic feature of ASD. Quantitative genetic research on ASD has overlooked these symptoms, however. We therefore investigated the association between autistic traits and SR using twin methods. Method: Autistic traits and SR were assess
Se-methyl L-selenocysteine (MeSeCys) is one of the major organic selenium compounds acquired from the diet by human beings. It has been shown to have anticancer activity and cancer prevention functions. However, its antioxidant activity, largely related to its biological function, has not been well characterized so far. We here report a stopped-flow kinetic study of the reduction of the Pt(IV) antSe-methyl L-selenocysteine (MeSeCys) is one of the major organic selenium compounds acquired from the diet by human beings. It has been shown to have anticancer activity and cancer prevention functions. However, its antioxidant activity, largely related to its biological function, has not been well characterized so far. We here report a stopped-flow kinetic study of the reduction of the Pt(IV) ant
A cluster of metabolic factors have been merged into an entity named the metabolic syndrome. Although the characteristics of this syndrome have varied over time the presently used definition was established in 2009. The presence of three abnormal findings out of five components qualifies a person for the metabolic syndrome: elevated waist circumference, elevated triglycerides, reduced high-density
BACKGROUND: Amyloid-β positron emission tomography (PET) and cerebrospinal fluid (CSF) Aβ42 are considered interchangeable for clinical diagnosis of Alzheimer's disease. OBJECTIVE: To explore the clinical reasoning for requesting additional amyloid-β PET after performing CSF biomarkers. METHODS: We retrospectively identified 72 memory clinic patients who underwent amyloid-β PET after CSF biomarker
Background—Mechanical chest compression (CC) is currently suggested to deliver sustained high-quality CC in a moving ambulance. This study compared the hemodynamic support provided by a mechanical piston device or manual CC during ambulance transport in a porcine model of cardiopulmonary resuscitation. Methods and Results—In a simulated urb
In order to investigate the molecular basis for the ability of the human B1 and B2 bradykinin (BK) receptor subtypes to discriminate between subtype- selective ligands, we constructed chimeric proteins in which the sixth transmembrane domains (TM-VI) of these receptors were exchanged. The pharmacological profiles of the constructs were analyzed by radioligand binding in particulate preparations of
BACKGROUND: No comprehensive collection of routine therapeutic drug monitoring data for antipsychotic drugs has been published. METHODS: In this compilation, data on 12 antipsychotics are presented. The drugs included are amisulpride (n = 506), aripiprazole (n = 1610), clozapine (n = 1189), flupentixol (n = 215), haloperidol (n = 390), olanzapine (n = 10,268), perphenazine (n = 1065), quetiapine (
IntroductionConsidering that on average in developed countries we spend about 65% of our time in private homes, understanding the exposures in homes is of outmost importance. Aerosol concentrations indoors come from indoor sources, infiltrate from outdoors and can be formed from precursors both of indoor and outdoor origin. Several characteristics and processes influence the properties of aerosols
The effect of neurotrophic factors on neuropeptide Y (NPY) expression was studied in adult rat dispersed dorsal root ganglion (DRG) cultures. Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), acidic fibroblast growth factor (aFGF) or basic FGF was included in the culture medium during incubation for 72 h. In untreated cultures, around 18% of all neurones (visualized by antibodie
