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Background: Prediction tools that combine polygenic risk scores with clinical factors provide a new opportunity for improved prediction and prevention of atherosclerotic cardiovascular disease, but the clinical utility of polygenic risk score has remained unclear. Methods: We collected a prospective cohort of 7342 individuals (64% women, mean age 56 years) and estimated their 10-year risk for athe
Domestic violence is an increasingly common problem in our society. In 2012 there were 28,400 cases reported of assault against women over 18 and almost half of these women reported having been abused by a loved one. In support of these women there is sheltered accommodation around the country, about half of Sweden's municipalities have a shelter for women and these are conducted both municipa
Measuring and monitoring socioeconomic health inequalities are critical for understanding the impact of policy decisions. However, the measurement of health inequality is far from value neutral, and one can easily present the measure that best supports one's chosen conclusion or selectively exclude measures. Improving people's understanding of the often implicit value judgments is therefore import
Solar energy is a renewable energy source which in the long term is important to develop because the usage does not effect the environment in a negative way. Increased energy exchange and cheaper production costs for solar collectors and solar cells are main factors in making the solar energy commercially successful in the future. Small scale solar collector systems are most common today because t
EU-domstolen har behandlat idrottens kommersiella inslag och dess särart i flera rättsfall. I Walrave-målet fastslog domstolen att idrott inte per automatik omfattas av unionsrätten, men att vissa idrottsliga intressen kan vara legitima syften inom unionsrätten. I Bosman-målet utvecklade dom-stolen teorin om idrottens särart och betonade dess sociala betydelse. I Meca-Medina-målet bekräftade domstThe Court of Justice of the European Union (CJEU) has dealt with the commercial elements of sport and its unique nature in several legal cases. In the Walrave case, the Court ruled that sport is not automatically covered by EU law but that particular sporting interests can be legitimate purposes within EU law. In the Bosman case, the Court developed the theory of the unique nature of sport and emp
From a small stream draining an agricultural catchment area in south Sweden, a temporal analysis of the occurrence of legacy pesticides was carried out and correlated with contemporary groundwater levelling, precipitation and flow rate of the stream, in order to evaluate groundwater outflow as an entry route for pesticides in the stream. Based on continuous measurement data from two periods of 12
With increasing competition and noise level in the third sector, Germany’s non-profit organisations have to start considering alternative ways of how to be heard by their target audiences and how to raise funds for their projects. Additionally, with technological developments and the rise of Web 2.0 this becomes particularly challenging. Strategic planning of communication and public relations act
Title: Homeless in Lund – a qualitative study of controlling institutions structuring everyday life in lack of a home Authors: Amanda Kalén and Desire Turesson Supervisor: Norma Montesino Assessor: Mats Hilte A home is far more than just a building. A home is where you can create your everyday-life and a place to relax. When you think of a daily routine, a house is almost always the place that
In this thesis, the Arctic sea ice volume and thickness evolution over the time period 1850-2100 is analysed. The analysed data is provided by the CMIP5 climate models, which contributed their output for the IPCC Fifth Assessment. The results were compared to the reanalysis data series PIOMAS. Three RCP projections, with different greenhouse gas emission scenarios, were used for the time period 20
Today a dynamic analysis is often performed with the use of advanced finite element software. An advanced model normally produces precise results. Analyzing these large models of bridges is however time consuming and a detailed description of the geometry, supports and material properties must be known. In an early stage of a project a reduced model could significantly reduce the time needed to perf
Recent years increase in biofuel production is contributing to the aim of reducing use of fossil fuels. The increase has, however, led to controversies due to effects on ecological and social aspects of sustainability. In 2010 the EU Renewable Energy Directive (EU-RED) was developed. The EU-RED intends to promote the use of energy from renewable sources, including renewable energy for the transpor
Many flying animals use both flapping and gliding flight as part of their routine behaviour. These two kinematic patterns impose conflicting requirements on wing design for aerodynamic efficiency and, in the absence of extreme morphing, wings cannot be optimised for both flight modes. In gliding flight, the wing experiences uniform incident flow and the optimal shape is a high aspect ratio wing wi
Diabetes Mellitus is a chronic disease of impaired blood glucose control due to degraded or absent bodily-specific insulin production, or utilization. To the affected, this in many cases implies relying on insulin injections and blood glucose measurements, in order to keep the blood glucose level within acceptable limits. Risks of developing short- and long-term complications, due to both too high
Background. Multidisciplinary team (MDT) conferences have been introduced into standard cancer care, though evidence that it benefits the patient is weak. We used the national Swedish Rectal Cancer Register to evaluate predictors for case discussion at a MDT conference and its impact on treatment. Material and methods. Of the 6760 patients diagnosed with rectal cancer in Sweden between 2007 and 20
In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. Using this method we inoculated rats with gel
It is hard to defend the view that biotic communities represent a simple and predictable response to the abiotic environment. Biota and the abiotic environment interact, and the environment of an individual certainly includes its neighbors and visitors in the community. The complexity of community assembly calls forth a quest for general principles, yet current results and theories on assembly rul
The focus of this work has been to implement a generic netlist reduction engine to speed up circuit simulations. The netlist reduction techniques are further optimized for Static Random-Access Memory (SRAM), wherein we exploit the repetitive pattern of the circuit. There are many driving factors for developing a netlist reduction engine for SRAM simulations. In today's System on Chip (SoC), S
Studiens syfte har varit att studera polisens reformarbete i den ungefärliga tidsperioden som sträcker sig de 100-åren mellan 1920-2020 med utgångspunkt från nationaliseringsreformen 1965. De frågeställningar som ligger till grund för att ta sig an materialet och som denna undersökning vill besvara är, hur uppstod och vad var syftet med polisens två stora reformer? Hur blev utfallet av dessa? Och,The purpose of this study have been to research the swedish police authority reforms in the approximate timespan of the 100-years that passed between 1920-2020. The starting point of the study has been set to the nationalisation-reform in 1965 although further inquiry into the years before was needed for context. The research issues at hand are, how did the nationalisation come to be? And what was
Our main purpose with this study is to examine and elucidate the recovery process that occurs when women choose to break up from destructive relationships. Our aim is also to clarify what, by the women themselves, is considered to be efficient help in relation to what in fact is offered in actuality. The idea of this selection was that we, in the study of the recovery process, would make a compili
Populärvetenskaplig sammanfattning: Platåleror utgör ett markant inslag i det inre backlandskapet söder om Romeleåsen i Skåne. De är kvadratkilometer stora, cirkulära lerområden, med en svagt undulerande yta som täcker landskapets högsta kullformer. Runt platålerorna ligger oftast s k kantryggar som huvudsakligen består av grus och sand. I snart hundra år har bildningsmiljön för platålerorna och kPlateau-clays are significant features in the hummocky moraine area south of Romeleåsen ridge, Skåne, southern Sweden. The plateau clays are smoothly undulating circular areas of glaciolacustrine clay, which drape the highest hummocks in the landscape. Rim ridges often surround the plateau-clays. During the last hundred years the formation of these plateau clays has been studied and discussed. In
