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Loss of appetite and negative energy balance are common features of endotoxemia in all animals and are thought to have protective roles by reducing nutrient availability to host and pathogen metabolism. Accordingly, fasting and caloric restriction have well-established anti-inflammatory properties. However, in response to reduced nutrient availability at the cellular and organ levels, negative ene
We present the catalog of optical and infrared counterparts of the Chandra COSMOS-Legacy Survey, a 4.6 Ms Chandra program on the 2.2 deg2 of the COSMOS field, combination of 56 new overlapping observations obtained in Cycle 14 with the previous C-COSMOS survey. In this Paper we report the i, K, and 3.6 μm identifications of the 2273 X-ray point sources detected in the new Cycle 14 observations. We
OBJECTIVE: A somatic mutational hotspot in the SF3B1 gene was reported in lactotroph tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a multicentre independent cohort of patients with lactotroph tumours and correlate with clinical data. DESIGN AND METHODS: This was a retrospective, multicentre study involving 282 patients with lactotroph tumours (including 6
Traumatic brain injury (TBI) has been named the most complex disease in the most complex organ of the body. It is the most common cause of death and disability in the Western world in people <40 years old and survivors commonly suffer from persisting cognitive deficits, impaired motor function, depression and personality changes. TBI may vary in severity from uniformly fatal to mild injuries with
Composition and functioning of arctic soil fungal communities may alter rapidly due to the ongoing trends of warmer temperatures, shifts in nutrient availability and shrub encroachment. In addition, the communities may also be intrinsically shaped by heavy grazing, which may locally induce an ecosystem change that couples with increased soil temperature and nutrients and where shrub encroachment i
Educational research in higher education needs a methodology for how to think and act in relation to how pedagogical interactions support learning. A methodology that can identify how pedagogical rhetorical qualities, such as confidence and a desire to learn, are embedded in a pedagogical interaction. This article presents an outline of a pedagogical rhetorical interactional methodology that enabl
Beviskravet i det svenska rättssystemet är högt ställt. För att utgången i ett mål ska bli fällande måste det vara ställt utom rimligt tvivel att en tilltalad har begått ett brott. Ändå finns det en rad fällande mål där den enda bevisningen som förekommit i målen har varit indiciebevisning. Indicier är ett mångtydigt begrepp, men i doktrinen definieras det som indirekta spår av en brottslig gärniThe evidentiary requirement in the Swedish legal system is set highly. For a defendant to be convicted for a felony, it needs to be set without reasonable doubt that the defendant committed the crime. Yet, there are several cases in which the defendant has been convicted for a felony with only circumstantial evidence in the case. Circumstantial evidence is an ambiguous concept but in the Swedish
The voting behavior of the Members of the European Parliament (MEP) has been widely studied. However, little is written about the effects of crises. This thesis tries to understand how the Covid-19 pandemic affected the MEPs voting behavior in relation to their European political group (EPG) and in addition their national party. This was done using the two theories: the two principal dilemma
En parts tillgång till information i en rättegång blir ofta avgörande för hur väl denne kan tillvarata sin rätt. Det är som huvudregel upp till parterna själva att anskaffa informationen, men det finns undantag. För de fall en informations-innehavare vid den utomprocessuella informationsanskaffningen inte med-verkar kan domstolen ibland bistå med informationsanskaffningen. InformationsanskaffningA party's access to information is crucial within the litigation process. In the event of a legal dispute, the main rule is that the parties must take care of gathering the necessary information on their own. However, there are exceptions. For those cases where the information holder does not cooperate, the court can assist with the information-gathering. Obtaining information in the event of
This research used a qualitative approach, more specifically, netnography based on two cases. The two empirical cases on the use of brand activism on packaging that have been selected for this study are: (1) Walmart’s introduction of a ‘Celebration Edition’ Ice Cream for Juneteenth, and (2) Skittle’s introduction of a rainbow- free packaging to support the LGBTQ+ community. Initially we analysed n
Ensuring food safety is an international goal and the Swedish national authority for food has just implemented a new system for risk-based food control. The new system for analyzing food businesses in a risk-based evaluation is based on EU-directives. The directive aims to use risk factors to evaluate food businesses when municipalities plan food safety inspections. In the former system for risk-b
This thesis extends Chinn & Kucko`s (2015) article which examines if a country's yield curve can predict its economic growth. The results show that Sweden's yield curve is not a particularly good predictor of the Swedish industrial production growth. In order to develop the article, the purpose of this thesis is to determine if the German and US yield curves can be used in order to pre
Cranioplasty is surgical repair of a skull bone defect due to a previous surgery or injury. Cranioplasty is most often performed with autologous bone flap, i.e the patient's own saved bone from previous surgery if this is available. If autologous bone is not available then custom procedure is to manually mould an implant using bone cement from the plastic polymethyl methacrylate (PMMA). Manual
This paper estimates the relationship between political instability and economic growth at the regional level. A panel of Swedish regions over the time frame 1994-2018 is used to conduct the empirical analysis. The empirical analysis consists of regressing regional growth rates in GDP per worker on a measure of political instability and a set of control variables. Growth rates are measured over a
Syftet med denna studie är att undersöka hur anhöriga upplever att leva bredvid en närstående med missbruksproblem. Samt vilket stöd de anhöriga fått från olika instanser som de har kommit i kontakt med i samband med deras närstående missbruk. Med studiens syfte som utgångspunkt valdes en kvalitativ forskningsansats och med självbiografier som empiriskt material. Jag har sedan valt två olika teoreThe purpose of this study is to investigate how relatives experience living next to close relative with substance abuse problems. And what the support the relatives have received from various agencies that they have come into contact with in connection with their related abuse. With the purpose of the study as a starting point, a qualitative research approach was chosen and with autobiographies as
The purpose of this study is to understand how alcohol culture in corridors is reproduced by applying Bourdieus and Durkheim's theoretical concepts. Furthermore, the study will analyze how people look at alcohol in relation to life situation, context, patterns of action and attitudes, which is important in understanding the statistics available and in order to counteract or encourage alcohol c
Skiljeförfarandet är ett eninstansförfarande som syftar till att snabbt och effektivt åstadkomma en slutlig och bindande skiljedom. Av denna anledning kan en skiljedom inte angripas på materiella grunder. Till skillnad från många utländska skiljeförfarandelagar har en part möjlighet att väcka både ogiltighets- och klandertalan mot skiljedomen som helhet eller i viss del, om skiljenämnden har brustArbitration is a single instance procedure aimed at achieving a final and binding award promptly and efficiently. For this reason, an arbitral award cannot be challenged on substantive grounds. Unlike many foreign arbitration laws, a party may bring an action for invalidity or an action to set aside an arbitral award, in whole or in part, if the arbitral tribunal has failed to comply with procedur
Effective preprocessing of electroencephalography (EEG) data is fundamental for deriving meaningful insights. Independent component analysis (ICA) serves as an important step in this process by aiming to eliminate undesirable artifacts from EEG data. However, the decision on which and how many components to be removed remains somewhat arbitrary, despite the availability of both automatic and manua
Objectives We aimed to compare various methods for imputing disease activity in longitudinally collected observational data of patients with axial spondyloarthritis (axSpA). Methods We conducted a simulation study on data from 8583 axSpA patients from ten European registries. Disease activity was assessed by the Axial Spondyloarthritis Disease Activity Score (ASDAS) and the corresponding low disea
Climate change and human activities threaten the availability and quality of fresh water resources globally, especially in less developed countries, where poverty and natural disaster risks are present. Despite important research efforts, gaps still exist regarding the understanding of the spatial-temporal variations of water quality and the movement of organic matter within tropical mountain lake
