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One way to assess the uncertainty in fatigue damage analysis is to use a so-called safety index. In the computation of such an index the coefficient of variation for the accumulated damage is needed. Employing the rainflow cycle count method for fatigue damage leads to, in most cases, complicated calculations. Here we present a new and simplified method to estimate the coefficient of variation for
Glial cells support neuronal survival and function by secreting neurotrophic cytokines. Retinal Mueller glial cells (RMGs) support retinal neurons, especially photoreceptors. These highly light-sensitive sensory neurons receive vision, and their death results in blinding diseases. It has been proposed that RMGs release factors that support photoreceptor survival, but the nature of these factors re
The actors in focus here are the citizens and the politicians. We are studying their opinions on two central issues of health-care policy during the period 1981-1991. The aims of the dissertation can be summarised as follows: - to study the compositions of citizens´attitudes to health-care provision and policy - to examine the value of using different methodical approaches when studying health-car
This text contains an overview of the field of frost and salt-frost resistance of concrete. It consists of three parts: First, a summary of known phenomena of frost and salt frost deterioration of concrete, then a description of thermodynamics of ice formation in porous materials, and finally a description of proposed models and mechanisms of deterioration during frost and salt frost attack. The c
Popular Abstract in Swedish I och med att mjukvarubaserade produkter ökar i antal ökar också vikten av en effektiv mjukvaruutvecklingsprocess, ur ett konkurrensperspektiv. Bristfällig produktkvalitet och höga utvecklingskostnader är något som mjukvaruutvecklingsorganisationer under många år har kämpat med. Studier inom SPI (software process improvement) syftar till att förbättra produktkvalitet ocThe number of software-based products is increasing, which is why the importance of an efficient software development process is also increasing, from a competitive advantage perspective. For years, software development organizations have been plagued by poor product quality and high development costs. Studies in software process improvement (SPI) have concerned themselves with improving the softw
The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei
The three-dimensional structure of the major birch pollen allergen, the 17,500 M(r) acidic protein Bet v 1 (from the birch, Betula verrucosa), is presented as determined both in the crystalline state by X-ray diffraction and in solution by nuclear magnetic resonance (NMR) spectroscopy. This is the first experimentally determined structure of a clinically important inhalant major allergen, estimate
Human jejunal tissue obtained by peroral biopsy was cultured in control medium and in medium containing 100 mmol l-1 ethanol. Subsequently, the incorporation and metabolism of [3H]-arachidonic and [14C]-linoleic acid were evaluated. Of the two fatty acids a significantly higher amount of [3H]-arachidonic acid was incorporated into phospholipids and more [14C]-linoleic acid was incorporated into tr
The paper analyses the historical development of Article 11 TFEU’s integration obligation and the intentions of Member States when adopting the various amendments to answer the question whether Article 11 TFEU applies across the board or only to certain specific areas of competences. The paper focuses in particular on the amendments of the Amsterdam and Maastricht Treaty as the most important chan
Abstract: Soft and biological materials are often composed of elementary constituents exhibiting an incessant roto-translational motion at the microscopic scale. Tracking this motion with a bright-field microscope becomes increasingly challenging when the particle size becomes smaller than the microscope resolution, a case which is frequently encountered. Here we demonstrate squared-gradient diffe
Associations are not random. Semantic memory is structured in a way that when hearing a category name a listener will automatically think of exemplars belonging to this category. The order in which exemplars come to mind and the frequency of retrieval of exemplars across individuals are measures of category-exemplar associative strength. Associative strength affects a broad range of psychological
To characterize the sites on the protein surface that are involved in the adsorption to silica nanoparticles and the subsequent rearrangements of the protein/nanoparticle interaction, a novel approach has been used. After incubation of protein with silica nanoparticles for 2 or 16 h, the protein was cleaved with trypsin and the peptide fragments were analyzed with mass spectrometry. The nanopartic
We report the presence of platelet-activating factor (PAF-acether; l-0-alkyl-2-acetyl-.v«-glycero-3-phosphocholine) in small-intestinal and colonic mucosa of neonatal rats. The PAF-acether content was higher in the colon than in the small intestine, and was lower in the small intestine of 30-day-old animals than in 14-day-old animals. We also report that cultured intestinal epithelial cells (INT 4
All people are different. All teachers are different. All students are different. They have different life situations, different study situations, and different preferences, conditions, and abilities. How can we take this diversity into account when we plan our teaching and exams? What situations should we prepare for? How can we help students focus on their learning and not on unnecessary obstacl
We assemble the Irish industrial data currently available for the years 1800-1921, the period during which the entire island was in a political Union with Great Britain, and construct an annual index of Irish industrial output for 1800-1913. We also construct a new industrial price index. Irish industrial output grew by an average of 1.3 per cent per annum between 1800 and the outbreak of the Firs
Over the last decades there has been a dramatic increase in the incidence of some diseases associated with the male reproductive system, including poor semen quality, testicular cancer and congenital developmental abnormalities such as cryptorchidism and hypospadias, malformations of the urethra and scrotum respectively. Based on these observations one recurring theme is the concern that certain e
Abstract in UndeterminedCaring for intensive care patients involves extensive use ofmedical technology. When staff are educated in workingwith these devices, the focus is on practical management.The context in which they are used is however verycomplex and the device cannot be seen as a separatecomponent. Knowledge about for example the patient’smedical status and background must also be considere
