Filtyp
The Islamic Republic of Iran (IRI) has employed assassinations and proxy violence as tools of statecraft. Dissidents in exile have been killed, targeted, or systematically threatened, while Israeli-linked entities across Europe have faced repeated attacks. In recent years, Tehran has increasingly outsourced these operations to state-linked criminal intermediaries. This paper analyzes Iran’s approa
Robots operating in real-world settings must manage task variability, environmental uncertainty, and failures during execution. This thesis presents a unified framework for building self-reliant robotic systems by integrating symbolic planning, reinforcement learning, behavior trees (BTs), and vision-language models (VLMs).At the core of the approach is an interpretable policy representation based
BACKGROUND: The Scandinavian Neurotrauma Committees (SNC) guideline is a validated and well established decision tool for pediatric minor to moderate head trauma in Sweden, categorizing patients into low, moderate and high risk for intracranial injury. It recommends observation over imaging with computer tomography in low and moderate risk stratified patients. However the effect on guideline imple
Deep learning has advanced flood forecasting through its strong nonlinear modeling capabilities. However, accuracy declines and robustness remain insufficient at longer forecast lead times. Therefore, an evolutionary deep learning model for flood forecasting was developed by integrating time-varying filter-based empirical mode decomposition (TVFEMD), sample entropy-based signal reconstruction (SE)
BACKGROUND: The Leiden group and the Assessment of Spondyloarthritis International Society (ASAS)-MRI study group have proposed definitions for structural (SL) and active (AL) lesions typical for axial spondyloarthritis (axSpA) on MRI of the sacroiliac joints (MRI-SIJ).OBJECTIVES: To analyse the predictive validity of proposed SL and AL MRI-SIJ definitions in early axSpA and compare proposed AL wi
Background: Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) frequently co-occur in youth. Integrated, trauma-focused treatments are recommended, but evidence in youth is limited and the dynamics of symptom change are poorly understood.Objectives: We investigated within-treatment changes in PTSD and substance use, and their temporal sequencing, in a randomised controlled tria
Background: Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited with respect to SBRT as a re-irradiation salvage therapy. We performed a systematic review and meta-analysis as basis for joint ESTRO-ISRS clinical practice recommendations of salvage SBRT for spinal metastases. Methods: A systematic review
BACKGROUND AND OBJECTIVES: Iron deficiency anaemia is common in patients recovering from major surgery and is associated with poorer post-operative outcomes. We designed a randomized controlled trial treating post-operative anaemia with iron therapy to observe the influence on post-operative recovery.MATERIALS AND METHODS: Anaemic patients (haemoglobin [Hb] < 120 g/L for women, Hb < 130 g/L for me
Urbanization is driving cities to grow, often through urban densification. Utilising computer-based simulations executed over 3D representations of the city is imperative in addressing the challenges posed by implementing sustainable urban densifications; like ensuring adequate access to daylight and limiting noise pollution. However, since these simulations are usually resource-intensive, timecon
Herein, we present a case of severe immune-related adverse events (irAEs), myocarditis with myositis, and myasthenia gravis overlap syndrome (IM3OS) in a patient receiving an immune checkpoint inhibitor (ICI), as adjuvant therapy after surgery for muscle-invasive bladder cancer. An 80-year-old woman who had undergone a total cystectomy for bladder cancer presented with ptosis, diplopia, and paraly
Background: Intracerebral hemorrhage (ICH) survivors are at increased risk of major adverse cardiovascular and cerebrovascular events (MACE) compared with population controls; however, little is known about the annual rates and risk factors for MACE. Methods: We searched Medline, Embase, and trial registries systematically in April 2024 for studies of adults with ICH, reporting either a MACE compo
Even if much is known regarding the effects of internet-delivered cognitive behaviour therapy (ICBT) for depression there are several topics that have not been studied. In this factorial design trial with 197 participants we investigated if clients in ICBT could select treatment modules themselves based on a selection of 15 tailored treatment modules developed for use in ICBT for depression. We co
Rapporten visar att det finns en gedigen vetenskaplig evidensbas för att utforma åtgärder inom den gemensamma jordbrukspolitiken som bidrar till restaurering av jordbrukslandskap i linje med EU:s naturrestaureringsförordning. Evidensbasen kan stärkas genom en systematisk sammanställning av resultat från restaureringsprojekt, och författarna föreslår adaptiv restaurering för att hantera kontextbero
BACKGROUND: Drug-coated devices are widely used to reduce restenosis after lower limb revascularisation in patients with peripheral artery disease, but their effect on patient-centred outcomes remains unclear. We assessed the effect of paclitaxel-coated devices on clinically important outcomes in patients with intermittent claudication undergoing infrainguinal endovascular revascularisation.METHOD
Decarbonising the global housing stock is imperative for reaching climate change targets. In the United Kingdom, hydrogen is currently being tested as a replacement fuel for natural gas, which could be used to supply low-carbon energy to parts of the country. Transitioning the residential sector towards a net-zero future will call for an inclusive understanding of consumer preferences for emerging
ObjectiveTo evaluate if adding esketamine and clonidine has positive effects on postoperative pain, postoperative nausea and vomiting, and quality of recovery in patients who are at high risk for postoperative pain.DesignPatient- and assessor-blinded, superiority, randomised controlled trial.SettingSingle centre between 2022 and 2024.Patients125 adult patients, ASA I – II, planned for elective lap
Objective: To estimate the effect on healthcare resource use after introducing the World Health Organization diagnostic criteria (WHO-2013) for gestational diabetes mellitus (GDM) compared to former criteria in Sweden (SWE-GDM). Design: A cost-analysis alongside the Changing Diagnostic Criteria for Gestational Diabetes (CDC4G) randomised controlled trial. Setting: Sweden, with risk-factor based sc
In this research, a straightforward and effective preconcentration technique was developed by integrating three-phase hollow fiber liquid-phase microextraction (HF-LPME) with high-performance liquid chromatography equipped with a photodiode array detector and mass spectrometry (HPLC-DAD/MS) for the simultaneous extraction and quantification of trace levels of tamoxifen (Tam) and clomiphene (Clom)
