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A critical factor in analyzing the propagation of activation waves in the myocardium is the definition of local activation times (LAT) in the electrogram. The authors have formulated and tested a definition of LAT in bipolar electrograms applicable to atrial electrograms containing deflections with wide variation in complexity, e.g. those obtained during rapid, irregular atrial rhythm, i.e. atrial
Deep and rapid decarbonization of the building sector requires energy demand reductions and the incorporation of renewable-energy sources. Energy retrofitting of existing buildings is a central strategy in climate mitigation and has often been highlighted as a cost-effective strategy. However, decisions on these strategies are often hampered by modeling assessments that are limited by contextual,
We consider Bayesian inference for stochastic differential equation mixed effectsmodels (SDEMEMs) exemplifying tumour response to treatment and regrowth in mice. We produce an extensive study on how an SDEMEM can be fitted by using both exact inference based on pseudo-marginal Markov chain Monte Carlo sampling and approximate inference via Bayesian synthetic likelihood (BSL). We inv
BACKGROUND: Artificial intelligence (AI) systems performing at radiologist-like levels in the evaluation of digital mammography (DM) would improve breast cancer screening accuracy and efficiency. We aimed to compare the stand-alone performance of an AI system to that of radiologists in detecting breast cancer in DM.METHODS: Nine multi-reader, multi-case study datasets previously used for different
Cognitive behavioral therapy (CBT) designed to target Generalized Anxiety Disorder (GAD) in youth was examined in a pilot feasibility trial. Participants (aged 10-18 years) were randomized to either 10 weeks of individual CBT (n = 20) or supported wait-list (n = 20). Diagnostic status (primary outcome) was assessed blindly at post-treatment for both groups, and at a 3-month follow-up for treated p
Bouts of excessive worry are common across the lifespan, increasing in frequency and complexity during adolescence and adulthood, and are found in several psychiatric disorders, particularly the anxiety disorders. There are evidence-based treatments for adolescents with anxiety disorders but psychological treatments designed specifically to target excessive worrying in adolescents are rare. Intole
Introduction: About 70 million people worldwide are estimated to suffer from epilepsy. Despite a large variety of old and new antiepileptic drugs on the market, about 30% of people with epilepsy do not become seizure-free with medical treatment. This is a major individual and public health burden. Most of these difficult-to-treat patients are having focal seizures. Zonisamide is effective against
In large software organizations with a product line development approach, system test planning and scope selection is a complex tasks for which tool support is needed. Due to repeated testing: across different testing levels, over time (test for regression) as well as of different variants, the risk of double testing is large as well as the risk of overlooking important tests, hidden by the huge a
Uncertainty rules supply chains. Unexpected changes constantly occur on all levels; strategically through globalization, introduction of novel technology, mergers and acquisitions, volatile markets, and on an operational level through demand fluctuations, and events such as late arrival of in-bound material, machine equipment breakdown, and quality problems. The problem with uncertainty is increas
This paper presents a data-aided Carrier Frequency Offset (CFO) estimation algorithm targeting the Wideband OFDM systems. Utilizing 3 consecutive preambles and processing them at frequency domain, the algorithm is robust to both Frequency Independent (F-I) and Frequency Dependent (F-D) I/Q Mismatch (I/Q-M). To evaluate the effectiveness of the proposed CFO estimation technique, we conduct extensiv
Renewable energy systems are likely to become wide spread in the future due to environmental demands. As a consequence of the dispersed nature of renewable energy systems, this implies that there will be a distributed generation of electric power. Since most of the distributed electrical energy sources do not provide their electric power at line frequency and voltage, a DC bus is a useful common c
The paper is in part an evaluation of using virtual focus groups in existing commercial platforms as a research method, in part a pilot study on motives and perceptions of Facebook users concerning political participation in social media. Two focus groups were set up in the commercial social network Facebook, consisting each of six participants, all of them residing in Sweden. One of the groups co
The use of a hydrogen-sensitive palladium-metal oxide semiconductor (Pd-MOS) sensor in combination with a membrane for liquid-to-gas transfer for the detection of dissolved hydrogen was investigated. The system was evaluated with known concentrations of dissolved hydrogen in water. The lowest concentration detected with this set-up was 160 nM. The method was applied to monitoring of a laboratory-s
The TRIPS Agreement allows WTO Members to enact and apply appropriate domestic competition law to address IPR-related anti-competitive practices. However, these flexibilities in the TRIPS Agreement do not provide any specific guidance for WTO Members. The application of domestic competition law to IPR abuses in technology transfer varies a great deal between developed and developing countries, and
This paper describes the design, simulation and measurement of a GaN power amplifier suitable for envelope and phase signal combination. The low-frequency envelope signal is used to vary the gate (bias) voltage of the device, resulting in a pulse width modulated drain voltage, while modulation of supply voltage or current is avoided. The test circuit is implemented using a discrete GaN HEMT power
