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Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. Available treatments are only symptomatic and have severe side effects, while they also fail to provide adequate seizure control in a third of the patients. Therefore, a cure is yet to
Ekologisk kompensation innebär att naturvärden som går förlorade på en plats tillförs på en annan plats. Tanken är att exploatering av mark- och vattenområden på så vis ska kunna ske samtidigt som värdefull natur bevaras. Fungerar då styrmedlet som avsett? Ekologisk kompensation kan verka vara en enkel lösning på en svår målkonflikt men en lärdom från andra länder är att måluppfyllelsen ofta är lå
BACKGROUND: Quality of surgical care as a crucial component of a comprehensive multi-disciplinary management improves outcomes in patients with endometrial carcinoma, notably helping to avoid suboptimal surgical treatment. Quality indicators (QIs) enable healthcare professionals to measure their clinical management with regard to ideal standards of care. OBJECTIVE: In order to complete its set of
In recent years there has been a great deal of discussion on the potential for a shift away from modernistic or technocratic approaches to decisionmaking on risk towards more open, inclusive, and deliberative approaches. The authors consider (a) the reasons why some companies have taken the first step in this transition by exploring the potential of more open and communicative approaches to enviro
BACKGROUND AND OBJECTIVE: Although smoking is associated with an increased incidence of cardiovascular disease and death, many smokers remain healthy after many years of smoking. Our objective was to assess whether this variation is related to rate of decline of respiratory function. DESIGN: This was a population-based cohort study, its subjects being men born in 1914 from Malmo, Sweden. METHODS:
The possibility of improving an existing method, based on supercritical-fluid extraction (SFE) and microwave-assisted extraction (MAE), for the determination of banned azo dyes in leather has been studied. Thus, optimization of experimental conditions in different steps (degreasing, reduction, and extraction) of the analytical procedure was performed. The influence of different variables (reaction
Organically managed agroecosystems rely in part on biological control to prevent pest outbreaks. Generalist predators (Araneae, Carabidae and Staphylinidae) are a major component of the natural enemy community in agroecosystems. We assessed the seasonal dynamics of major generalist predator groups in conventionally and organically managed grass–clover fields that primarily differed by fertilisatio
In patients with severe head injuries raised intracranial pressure (ICP) constitutes the most important cause of mortality. Several new therapies for increased ICP have recently been suggested and it is of importance to study the physiological effects of these treatments in animal experiments during steady state conditions. A porcine model for evaluation of cerebral haemodynamics and metabolism du
This paper presents a computer-based decision support system for automated interpretation of diagnostic heart images (called WeAidU), which is made available via the Internet. The system is based on image processing techniques, artificial neural networks (ANNs) and large well-validated medical databases. We present results using artificial neural networks, and compare with two other classification
A small release cell, in the form of a rotating disc, has been constructed to fit into the MRI equipment. The present work show that both qualitative and quantitative information of the swelling and erosion behavior of hydrophilic extended release (ER) matrix tablets may be obtained using this release cell and non-invasive magnetic resonance imaging (MRI) studies at different time-points during ma
A resonator system has been fabricated directly on a pre-processed CMOS chip. The system is to be used for high sensitivity mass sensing applications in air and vacuum. The resonator system, corresponding of a cantilever and structures for electrostatic actuation and capacitive read-out, have been defined by electron beam lithography on top of a charge and radiation sensitive CMOS layer in predefi
Objective. Some monoclonal antibodies (mAb) to type II collagen (CII) are arthritogenic upon passive transfer to mice. We undertook this study to investigate whether such mAb are pathogenic in the absence of mediators of inflammation. Methods. The arthritogenic mAb CIIC1 and M2139, and the nonarthritogenic mAb CIIF4, each reactive with a distinct and well-defined conformational epitope on CII, wer
In this paper, six different strategies for integrated control of nitrate recirculation flow rate and external carbon addition in a predenitrifying biological wastewater treatment system are proposed and evaluated using the COST simulation benchmark. The proposed control strategies consist of two or three feedback control loops, which manipulate the nitrate recirculation and the carbon dosage flow
Water service delivery to most residents of peri-urban areas of greater Maputo depends largely on alternative service providers. mostly in the form of small-scale independent providers (SSIPs). This paper discusses the present and long-term challenges facing SSIPs in supplying quality water of sufficient quantity in peri-Urban Maputo and possible human health risks associated with the consumption
