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The purpose of this research was to investigate the geometrical accuracy of magnetic resonance (MR) images used in the radiation therapy treatment planning for lung cancer. In this study, the capability of MR imaging to acquire dynamic two-dimensional images was explored to access the motion of lung tumors. Due to a number of factors, including the use of a large field-of-view for the thorax, MR i

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This paper makes a case for using cost effectiveness (as opposed to efficiency) as key criterion when designing support policies for electricity generation from renewable energy sources in coexistence with an emissions trading scheme. Using the EU ETS and the German feed-in tariff system as examples, arguments against a stand-alone ETS are presented and necessary conditions for cost-effective supp

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Background: Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it. Objectives: To investigate whether consumers with undesirable effects after using the UV-curing nail

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In this paper, we study the block error rate (BLER) performance of spatially coupled low-density parity-check (SC- LDPC) codes using a sliding window decoder suited for streaming applications. Previous studies of SC-LDPC have focused on the bit error rate (BER) performance or the frame error rate (FER) performance over the entire length of the code. Here, we consider protograph-based constructions

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In this article, we argue for a conceptual move from family-centred care (FCC) to a child-centred care approach and the implications for clinical nursing practice. Firstly, we argue that the parents and professional dominance constructs an asymmetric relationship towards the child, which may take away the focus from the child; Secondly, we need to renew efforts to promote the fundamental principle

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An autoclavable all-glass system for studying microbial dynamics at permeable surfaces is described. Standard hydrophobic or hydrophilic membranes (46-mm diameter) of various pore sizes were supported on a glass frit through which nutrient solutions were pumped by a peristaltic pump. The pump provided a precisely controlled flow at speeds of 0.5 to 500 ml of defined or natural cell exudates per h,

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Human breast cancer is believed to arise in luminal progenitors within the normal breast. A subset of these are double positive (DP) for basal and luminal keratins and localizes to a putative stem cell zone within ducts. We here present a new protocol based on a combination of CD146 with CD117 and CD326 which provides an up to thirty fold enrichment of the DP cells. We show by expression profiling

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Sexuality is a taboo subject in disability services, leading to insecurity for both service users and personnel about how to handle upcoming situations. In Sweden, there is also a lack of policy in this area, highlighting the need to study sexuality both as an individual and a political, and in this case also, depoliticized issue. A critical feminist policy analysis reveals that norms around disab

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The isochore theory depicts the genomes of warm-blooded vertebrates as a mosaic of long genomic regions that are characterized by relatively homogeneous GC content. In the absence of genomic data, the GC content at third-codon positions of protein-coding genes (GC3) was commonly used as a proxy for the GC content of isochores. Oddly, in the postgenomic era, GC3 is still sometimes used as a proxy f

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A "genome order index," defined as S=a(2)+c(2)+t(2)+g(2), where a, c, t, and g are the nucleotide frequencies of A, C, T, and G, respectively, was used to suggest that there exist genome-specific constraints on nucleotide composition. We show that the "evidence" for constraint, S<1/3, is in fact a mathematical property that is always true regardless of data. Moreover, we show that S is strictly eq

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Gastric cancer (GC) is the fifth most common type of cancer worldwide with high incidences in Asia, Central, and South American countries. This patchy distribution means that GC studies are neglected by large research centers from developed countries. The need for further understanding of this complex disease, including the local importance of epidemiological factors and the rich ancestral admixtu

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Systemic sclerosis (SSc) is an autoimmune disease that shows one of the highest mortality rates among rheumatic diseases. We perform a large genome-wide association study (GWAS), and meta-analysis with previous GWASs, in 26,679 individuals and identify 27 independent genome-wide associated signals, including 13 new risk loci. The novel associations nearly double the number of genome-wide hits repo

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En ökning av andelen kollektivtrafik är en viktig del av omställningen mot lägre utsläpp av växthusgaser och mer energieffektiva transporter. I Sverige har antalet resor med kollektivtrafiken ökat med 18% mellan åren 2009 och 2015. Det finns dock en stor skillnad mellan olika regioner där ökningen varit över 20% i flera regioner medan utvecklingen av resandet har stagnerat, eller till och med mins

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Behandling av patienter med alkohol- eller drogberoende är en komplex flerstegsprocess som behandlar både substansberoende och co-morbiditeter. Riskfyllda livsstilar, inklusive tobaksrökning, otillräcklig fysisk aktivitet och ohälsosam kost, som kan förvärra hälsotillståndet och själva beroendebehandlingen, är mycket vanligt bland dessa patienter. Det komplexa hälsofrämjande programmet (Very IntegTreatment of patients with alcohol or drug use disorders is a complex multistage process addressing the substance addiction and co-morbidities. The risky lifestyles, including tobacco smoking, insufficient physical activity and unhealthy diet, which can aggravate health condition as well as addiction treatment itself, are very common among these patients. The complex health promotion (Very Integra

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Temperature and precipitation extremes are the dominant causes of natural disasters. In this study, seven indices of extreme temperature and precipitation events in Gansu Province, China, were analysed for the period 1961–2017. An abrupt climate shift was recorded during 1980–1981. Thus, the study period was divided into a preshift (before the climate shift) period 1961–1980 and an aftshift (after

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Laser cooling is a well-established technique for the creation of ensembles of ultracold neutral atoms or positive ions. This ability has opened many exciting new research fields over the past 40 years. However, no negatively charged ions have been directly laser cooled because a cycling transition is very rare in atomic anions. Efforts of more than a decade currently have La- as the most promisin