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Unexpected events should be seen as an opportunity to learn for increased safety in the future, but many accidents actually happen because of lack of learning. This study focuses on learning in the railway sector based on insight into the current implementation work of the recommendations that follow the Swedish Accident Investigation Board's (SHK) investigations. A content analysis of SHK'

Bakgrund:
Samhällsbyggandet har kritiserats för bristande konkurrens, kvalitet, effektivitet och kompetens. För att effektivisera byggprocessen och sänka byggkostnaderna krävs medvetenhet om logistiken och dess påverkan på en byggarbetsplats. Andra företeelser som påverkar kostnader och effektivitet på byggarbetsplatser är samverkan, kommunikation och planering. En av de planer som tas fram fö

Etableringsfriheten för företag är en av de mest fundamentala rättigheterna i Lissabonfördraget. Fördragets artiklar utgör grunden för rättigheten och ger företag rätt att starta eller driva verksamhet i vilken medlemsstat som helst i EU utan att diskrimineras. Denna rättighet har ytterligare utökats genom införandet av nya företagsformer och genom harmonisering av bolagsrätten i ett flertal direkThe freedom of establishment for companies is one of the fundamental rights enshrined in the FEU Treaty. The provisions of the Treaty set out the basis for the right and give companies the freedom to take up and pursue activities in any Member State of the EU without being discriminated. This right has been further expanded through the adoption of new company forms as well as harmonised through se

The mass production of plug-in electric vehicles (PEVs) is expected to start in the coming years. Climate change, peak oil and the automotive and economic crisis have put a significant pressure on the current transportation regime. Increasing urbanisation, range and efficiency advantages of PEVs in city traffic and the problem of urban air pollution have moved cities into the focus of PEV dissemin

An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbourin

This article presents the methodological requirements for clinical examination and patient-reported outcomes measurements. The assessment of any measurement for clinical research in hand surgery is difficult. A method of measuring a criterion could be 100% reliable but 100% invalid. Bias may be present in our assessment if we do not take into account the methodological requirements related to reli

Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insulin deficiency and type 1 diabetes (T1D)1-4. Certain enteroviruses can infect β cells in vitro5, have been detected in the pancreatic islets of patients with T1D6 and have shown an association with T1D in meta-analyses4. However, establishing consistency in findings across studies has proven difficul

On the 20th anniversary of the euro, this column traces public support for the single currency and public trust in the ECB. The crisis years slightly dented support for the euro while trust in the ECB fell sharply. The recovery increased support for the euro, but while trust in the ECB has also risen, it remains below its pre-crisis levels. Unemployment is the key factor driving public support for

Ecdysteroids are critically important for formation of the insect exoskeleton. Cholesterol is a precursor of ecdysone and its active form 20-hydroxyecdysone, but some steps in the ecdysteroid biosynthesis pathway remain unknown. An essential requirement of glutathione transferase GSTE14 in ecdysteroid biosynthesis has been established in Drosophila melanogaster, but its function is entirely unknow

User generated content (UGC) makes up a significant portion of Internet traffic. As opposed to other content, UGC has so far been left outside over-the-top providing network operators content distribution networks (telco-CDN) due to the difficulty in determining optimised placement of such content. The side effect of this is that UGC content is not placed close to end users and therefore occupy un

Vegetation growth in Soil and Water Assessment Tool (SWAT) is a crucial process for quantifying ecohydrological modelling, as it influences evapotranspiration, interception, soil erosion and biomass production. The simplified version of Environmental Policy Integrated Climate (EPIC) in SWAT was originally designed for temperate regions and naturally based on temperatur

Precipitation data at high spatio-temporal resolution are essential for hydrological, meteorological, and ecological research in local basins and regions. The coarse spatial resolution (0.25°) of Tropical Rainfall Measuring Mission (TRMM) 3B43 product is insufficient for practical requirements. In this paper, a multivariable geographically weighted regression (GWR) downscaling method was developed

The cover and management factor (C) of the Universal Soil Loss Equation (USLE) is difficult to be estimated over broad geographic areas where meteorology and soil erosion are poorly monitored. This paper presents a new approach to estimate C factor based on multi-temporal images of Landsat TM/ETM and a weather generator. The linear spectral unmixture algorithm was adopted to calculate the fraction

Standard Model events with prompt, isolated, same-charge high-pT leptons are rare, and therefore events with such final states provide a powerful signature towards new discoveries. This thesis presents two searches for doubly charged Higgs bosons decaying into same-charge lepton pairs using proton–proton collision data recorded by the ATLAS detector at the LHC. Observation of doubly charged Higgs

The galectins are a family of galactose-binding proteins playing key roles in inflammatory processes and cancer. However, they are structurally very closely related, and discovery of highly selective inhibitors is challenging. In this work, we report the design of novel inhibitors binding to a subsite unique to galectin-3, which confers both high selectivity and affinity towards galectin-3. Olefin