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BACKGROUND: Lung cancer remains one of the most challenging diseases to treat due to its heterogeneity. Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations are genetic drivers in numerous cancer types including lung adenocarcinoma (LUAD). Despite recent advances in KRAS-targeted therapies, treatment resistance and limited therapeutic options necessitate advanced preclinical models, such as

This is a poster presentation of the project RIGHydro for the MissionGreenFuels Annual Meeting 2025. The project RIGHydro is funded by the Innovation Fund Denmark.The Project "Regulatory Innovation to Incentivize Green Hydrogen" (RIGHydro) aims to contribute to the deployment of green hydrogen as a key component of the green transition in Denmark, the EU and beyond. Through an analysis of the late

Context. The increased brightness temperature of young rocky protoplanets during their magma ocean epoch makes them potentially amenable to atmospheric characterization at distances from the Solar System far greater than thermally equilibrated terrestrial exoplanets, offering observational opportunities for unique insights into the origin of secondary atmospheres and the near surface conditions of

Semi-open ecosystems, such as savannas and open woodlands, are biodiversity hotspots due largely to their heterogeneous tree cover (TC), which supports diverse habitats. However, increasing woody encroachment is altering TC heterogeneity, with unclear consequences for ecosystem stability. Using global satellite-based TC estimates (2000–2020), we reveal widespread TC homogenization (24.1%) in semi-

Dust burden during the dust storms events imparts an adverse effect on human health and environment. The aim of this research is to provide a deeper understanding about the atmospheric dynamics of long-range transport of mineral dust for 8 severe dust storm events over the Indian region during the period 2008–2022. Transport of mineral dust analyzed based on MERRA-2 Dust column mass density, follo

In this study, a coupled transient thermomechanical finite element model is developed to examine the laser powder bed fusion (L-PBF) process of the Inconel 718 (IN718) and Oxide Dispersion Strengthened (ODS) superalloys (ODS-IN718). The linear isotropic elastic perfectly plastic constitutive model is implemented for the mechanical part whereas all the thermophysical properties are defined as fully

This manuscript reports the results of an international consensus on technologies of hyperthermic intraperitoneal perioperative chemotherapy (HIPEC) performed with the following goals: To provide recommendations for the technological parameters to perform HIPEC. To identify the role of heat and its application forms in treating peritoneal metastases. To provide recommendations regarding the correc

The automotive domain is becoming increasingly complex through the integration of new technologies. As a result, cybersecurity is recognized as a pressing issue. This study focuses on the ISO/SAE 21434:2021 standard for road vehicles cybersecurity engineering, evaluating the effectiveness of the standard’s risk assessment approach. The standard suggests a set of assessment steps, and previous rese

This paper looks at the role of gender in the shaping and exercise of political authority. Its empirical focus is a slum in central Trivandrum, Kerala's capital city, which is undergoing a phased process of formalisation and rebuilding funded through a flagship Indian national programme, the JNNURM. The upgrade project should offer a dense network of ‘invited’ spaces for female participation withi

Marine and salt marsh sediments contain large amounts of organic carbon (OC) and are therefore important in the global carbon cycle. Here, we collated previously published and unpublished measurements of sediment OC in marine and salt marsh sediments in European regional seas (EURO-CARBON; available at https://doi.org/10.5281/zenodo.14905489). To the extent possible the OC data were complemented b

Accurate prediction of spatial yield variations within individual fields is crucial for precision agriculture, as it enables optimized resource allocation and targeted crop management. In this study, we propose a novel framework that leverages remote sensing data and Graph Attention Networks (GATv2) to predict fine-scale yield variations for winter wheat at a high resolution (10 m × 10 m). The obj

Motivation can be a decisive factor in students’ learning of a foreign language. At the same time, motivation is complex, dynamic, and context sensitive (Papi & Hiver, 2020). Language teachers encounter a wide spectrum of motivational profiles among their students and need to understand the motivation process to find strategies to address students' varying levels of motivation at a given time.

The curve number (CN) method, developed by the Natural Resources Conservation Service (NRCS), is one of the most widely used approaches worldwide to estimate runoff from rainfall events. However, one of the remaining uncertainties in the method remains whether to apply a frequency-matched or natural data approach for computing the CN from rainfall-runoff data. To address this knowledge gap, this s

The mobilization of water has been key for the reconfiguration and modernization of the Spanish state. During the Francoist dictatorship (1939–1975), the hydro-social reengineering of Spain was central to Franco's political mission but failed to provide for subnational, regionalist aspirations which subsequently pursued their own agendas for water development. In this paper we examine the (failed)

For the first time, an IP created in China has become a global consumer craze. And it happened entirely without central planning.

Amyloid-β (Aβ) positron emission tomography (PET) imaging and cerebrospinal fluid (CSF) biomarkers are now established tools in the diagnostic workup of patients with Alzheimer's disease (AD), and their use is anticipated to increase with the introduction of new disease-modifying therapies. Although these biomarkers are comparable alternatives in research settings to determine Aβ status, biomarker