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Importance: Accurate blood-based biomarkers for Alzheimer disease (AD) might improve the diagnostic accuracy in primary care, referrals to memory clinics, and screenings for AD trials. Objective: To examine the accuracy of plasma β-amyloid (Aβ) and tau measured using fully automated assays together with other blood-based biomarkers to detect cerebral Aβ. Design, Setting, and Participants: Two pros
The project examines how grassroots organizations and networks providing urban critical services in informal settlements contribute to improve the quality of life of urban dwellers and to more inclusive forms of urban governance, constructing the city from below.The project is informed by the study of Kisumu’s informal settlements’ Resident Associations, the Water Delegated Management Model, and t
With the increased pressure and challenges of economic, environmental, and social character, the need for innovations (including both the generation and adoption of innovations) that can be implemented in supply chains increases. A number of novel concepts focusing on intelligent logistics and packaging systems are being developed and tested in the food industry, all over the world. Several of the
Genetic and environmental factors both contribute to the development of Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD). One suggested environmental risk factor for ASD and ADHD is air pollution, but knowledge of its effects, especially in low-exposure areas, are limited. Here, we investigate risks for ASD and ADHD associated with prenatal exposure to air polluti
Background: Staging of rectal cancer with MRI has major impact on treatment choice and may be of importance in new cancer management strategies such as “wait-and-see” policy. Purpose: To assess the reproducibility of a software package recently developed at our department to measure volumes, apparent diffusion coefficient, and the skewness of apparent diffusion coefficient in lymph nodes and tumor
The incidence of treatment-related neuroendocrine prostate cancer (t-NEPC) is rising as more potent drugs targeting the androgen signaling axis are clinically implemented. Neuroendocrine transdifferentiation (NEtD), an putative initial step in t-NEPC development, is induced by androgen-deprivation therapy (ADT) or anti-androgens, and by activation of the β2-adrenergic receptor (ADRB2) in prostate
Cardiac thromboembolism attributed to atrial fibrillation (AF) is responsible for up to one-third of ischemic strokes. Stroke may be the first manifestation of previously undetected AF. Given the efficacy of oral anticoagulants in preventing AF-related ischemic strokes, strategies of searching for AF after a stroke using ECG monitoring followed by oral anticoagulation (OAC) treatment have been pro
BackgroundGenesis of acquired epilepsy includes transformations spanning genetic-to- network-level modifications, disrupting the regional excitatory/inhibitory balance. Methodology concurrently tracking changes at multiple levels is lacking. Here, viral vectors are used to differentially express two opsin proteins in neuronal populations within dentate gyrus (DG) of hippocampus. When activated, th
Business travel contributes to significant greenhouse gas emissions, and there is a need for measures that reduce the demand for trips made with energy-intensive means of transport. In this study, a mobility service application (MSA) introduced in 13 Swedish organisations was tested and evaluated to facilitate booking and handling of business trips, in particular public transport. A before and aft
Background: There is a great unmet clinical need to identify patients with thin primary cutaneous melanomas (T1, Breslow thickness ≤ 1 mm) who have a high risk for tumor recurrence and death from melanoma. Kin of IRRE-like protein 1 (KIRREL/NEPH1) is expressed in podocytes and involved in glomerular filtration, but its expression in human cancer has not yet been reported. Screening in the Human Pr
The synthesis of two conformationally restricted Cr(III) salen complexes, 2 and 3, is described. Together, they constitute a supramolecular hydrogen-bonding catalytic system for the recently reported asymmetric ring-opening reactions of epoxides by a dynamic supramolecular catalyst. The synthesis involves state-of-the art transformations in frontline synthetic chemistry applied to heterocyclic che
Extracting information about emerging events in large study areas through spatiotemporal and textual analysis of geotagged tweets provides the possibility of monitoring the current state of a disaster. This study proposes dynamic spatio-temporal tweet mining as a method for dynamic event extraction from geotagged tweets in large study areas. It introduces the use of a modified version of ordering
Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune cells from blood and spleen. Using expression quantitative trait loci (eQTL) reported in these tissues, we identify 26 previously unreported, likely target genes of over
In this study, steady-state laminar natural convection of Cu and TiO 2 nanofluids inside different enclosures is numerically investigated. Natural convection is concerned due to a temperature difference between the hot and cold
Microsoft Word - CB 261217 LUCC-C symposium program 2026 LUCC-Child mini-symposium 2026 “CHILDHOOD CANCER CARE AND RESEARCH – PAST, PRESENT AND FUTURE” Dear all, we are pleased to invite you to a physical LUCC-Child mini-symposium, on Wednesday 25th of February 2026, from 13.30 to 18:30, followed by guided tour and dinner. We will meet at Skissernas Museum in central Lund, where we will also have
