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Within the family of voltage-gated calcium channels (VGCCs), L-type channels (L-VGCCs) represent a well-established therapeutic target for calcium channel blockers, which are widely used to treat hypertension and myocardial ischemia. L-VGCCs outside the cardiovascular system also control key physiological processes such as neuronal plasticity, sensory cell function (e.g. in the inner ear and retin
Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel i
Compact binary systems with neutron stars or black holes are one of the most promising sources for ground-based gravitational-wave detectors. Gravitational radiation encodes rich information about source physics; thus parameter estimation and model selection are crucial analysis steps for any detection candidate events. Detailed models of the anticipated waveforms enable inference on several param
This study was designed to evaluate feasibility and lymphatic complications of robotic pelvic and infrarenal paraaortic lymphadenectomy in endometrial cancer patients.
At subzero temperatures, cloud particles can contain both ice and liquid water fractions. Wet growth of precipitation particles occurs when supercooled cloud liquid is accreted faster than it can freeze on impact. With a flexible framework, the theory of wet growth of hail is extended to the case of the inhomogeneities of surface temperature and of liquid coverage over the surface of the particle.
A differential absorption lidar (DIAL) system based on a Nd:YAG laser pumped narrow-band dye laser is developed and employed to monitor the atmospheric background concentration of atomic mercury in Guangzhou, South China. Atmospheric oxygen is also studied by using neighboring wavelengths to the mercury absorption line (253.7 nm), and is used to verify the operation of the DIAL system. A 24-hour c
Alternating aromatic multiblock copolymers have been structurally designed to enable selective lithiation and subsequent anionic graft polymerization from only one of the two block types. The multiblock copolymers were prepared by coupling polyfluoroether (PFE) and polysulfone (PSU) precursor blocks under mild conditions. The judicious combination of blocks allowed for block selective lithiation o
The notion of spirit loss is widespread throughout the Bolivian Andes. Because of fright, a person loses her spirit whereupon another "strange" spirit may take its place and cause illness. In one and the same ailment, then, we find notions of "loss" and "imposition." In the context of "emergent indigeneities," colonialism too is frequently visualized and expressed in terms of both loss and imposit
Treatment effects may not be observed if an empirically supported intervention is not administered with treatment adherence. This retrospective study investigated how therapists' adherence to Multisystemic therapy (MST) varied during a 6-year period in Sweden. Adherence was measured using the Therapist Adherence Measure, which was provided by caregivers. The associations between treatment adherenc
Self-diffusion in polymer solutions studied with pulsed-field gradient nuclear magnetic resonance (PFG NMR) is typically based either on a single self-diffusion coefficient, or a log-normal distribution of self-diffusion coefficients, or in some cases mixtures of these. Experimental data on polyethylene glycol (PEG) solutions and simulations were used to compare a model based on a gamma distributi
In the present paper we deal with integrators relying on Finite Elements in time for general hyperelastic models which guarantee the conservation of the momentum maps as well as of the total energy within the calculation accuracy. In the isotropic case, eigenvalue-based constitutive laws are, on the one hand, very significant to model the behaviour of various materials. On the other hand, it will
The Intermediate Data Structure (IDS) is a standardised database structure for longitudinal historical databases. Such a common structure facilitates data sharing and comparative research. In this study, we propose an extended version of IDS, named IDS-Geo, that also includes geographic data. The geographic data that will be stored in IDS-Geo are primarily buildings and/or property units, and the
The flexibility of implantable neural probes has increased during the last 10 years, starting with stiff materials such as silicone to more flexible materials like polyimide. We have developed a novel polymer based on Off-Stoichiometry Thiol-Enes + Epoxy (OSTE+, consisting of a thiol, two allyls, an epoxy resin and two initiators), which is up to 100 times more flexible than polyimide. Since a fle
A search is made for massive highly ionising particles with lifetimes in excess of 100 ns, with the ATLAS experiment at the Large Hadron Collider, using 3.1 pb(-1) of pp collision data taken at root s = 7 TeV. The signature of energy loss in the ATLAS inner detector and electromagnetic calorimeter is used. No such particles are found and limits on the production cross section for electric charges
This analytical essay critically examines how social sustainability is constructed within Lund’s municipality district development program for Norra Fäladen. The existing research widely acknowledges that sustainable development and social sustainability are characterized by conceptual ambiguity and a lack of consensus regarding definition and measurement. Despite this, they are leading concepts f
Denna uppsats analyserar hur rekvisitet ”särskilda skäl” ska tillämpas vid tvångsinlösen enligt ABL och vilka konsekvenser denna tillämpning får för tvångsinlöseninstitutets minoritetsskyddande funktion. Reglerna om tvångsin-lösen innebär att en aktieägare som innehar minst nio tiondelar av samtliga aktier kan tvinga återstående aktieägare att sälja sina aktier, samtidigt som mi-noriteten har rättThis thesis examines how the requirement of “particular grounds” is applied in buy-out proceedings under the Swedish Companies Act and what the ap-plication of this requirement implies for the minority-protective function of the buy-out. The rules on buy-out entitle a shareholder who holds at least nine tenths of all shares in a company to force the remaining shareholders to sell their shares, whi
Energieffektivisering har blivit en central del av Europeiska unionens klimat- och energipolitik som ett svar på klimatförändringar och resursknapphet. Genom energieffektiviseringsdirektivet (EED) har EU infört bindande mål för att minska energianvändningen och främja effektiv energianvändning som ett kostnadseffektivt sätt att minska utsläpp, stärka energisäkerheten och stödja hållbar utveckling.
Bakgrund: Hemlöshet utgör en komplex global samhällsutmaning. Individuella, politiska och sociokulturella faktorer begränsar hemlösa personers möjligheter att utöva sin rätt till aktivitet och hälsa i vardagen. Internationella studier indikerar att aktivitetsbaserade åtgärder kan vara gynnsamma för målgruppen, men mer samlad kunskap behövs för att stödja framtida studier som undersöker hur svenskaBackground: Homelessness constitutes a complex global societal challenge. Individual, political and socio-cultural factors limit homeless persons from exercising their right to activity and health in everyday life. International studies show that the use of occupation-based interventions may benefit the target group. Further evidence is needed to inform future studies investigating how Swedish occ
Bakgrund: Stresshantering är en av de största hälsoutmaningarna vi står inför i framtiden. Shinrin-yoku/Shinrin-ryoho har visat sig ha en positiv inverkan på personer med stressrelaterad ohälsa. Relationen mellan aktivitet, hälsa och välbefinnande är komplext. Forskning om skogsbad/skogsterapi har främst fokuserat på de fysiologiska effekterna och det saknas forskning inom den arbetsterapeuti
For the best start in life – An ethnological study into the choice of birth place. This ethnological essay aims to investigate and create a deeper understanding of the underlying reasons for different individuals' choices of birthing locations, and how they can possibly give us a deeper understanding of the ideals that exist within Swedish maternity care today. To answer this, I have intervie
