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Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio of forced expiratory volume in 1 second (FEV1)/vital capacity (VC), either as a fixed value 1/VC ratio in a general population setting. The second aim was to evaluate the characteristics of subjects with COPD who obtained a higher SVC than FVC. Methods: Subjects (n=1,050) aged 50-64 years were i
In this work, we present a detailed investigation of the growth of palladium-seeded GaAs nanowires. Nanowires grown on GaAs (111)B substrates consist of three different morphologies, denoted as curly (containing multiple kinks), inclined (relative to the substrate, such as 〈001〉), and vertical. We show that the relative yield of the different types is controllable by a combination of V/III ratio a
Background and purpose - Assessment of potential disparities in access to care is a vital part of achieving equity in health and healthcare. We have therefore studied the effect of socioeconomic status (SES) on the rates of knee and hip replacement due to osteoarthritis. Methods - This was a cohort study in Skåne, Sweden. We included all residents aged ≥ 35 years with consultations between 2004 an
BACKGROUND AND OBJECTIVE: Severe idiopathic pulmonary fibrosis is associated with an increased risk of cardiovascular disease and gastro-oesophageal reflux, which may influence prognosis. We evaluated associations between cardiovascular and antacid medications, and mortality, in oxygen-dependent pulmonary fibrosis (PF) of unknown cause.METHODS: Prospective population-based study of adults starting
Ischemic stroke is often associated with loss of cortical neurons leading to various neurological deficits. A cell replacement based on stem cell transplantation to repair the damaged brain requires the generation of specific neuronal subtypes. Recently, induced pluripotent stem cells have been used to generate various subtypes of neurons in vitro for transplantation in stroke-damaged brains. Howe
Even more than in developing countries today, public health strategies to fight infectious disease in the past focused on the prevention of new infections by stopping their spread. These strategies were motivated by new insights into the causes of disease and the modes of transmission in the mid-nineteenth century. By combining longitudinal individual-level data on 17,000 children in a rural/semi-
There is in large parts of the world a demographic crisis. Due to the increase in life length and the drop inbirth rates, prospects are that much fewer people of working age will be available in the future to supportthose in retirement.Also Sweden faces a demographic challenge, implying that it will be necessary to make the Swedeswork more years. There is an obvious potential in the age range 65-7
Background A 1-h algorithm based on high-sensitivity cardiac troponin T (hs-cTnT) testing at presentation and again 1 h thereafter has been shown to accurately rule out acute myocardial infarction. Objectives The goal of the study was to evaluate the diagnostic accuracy of the 1-h algorithm when supplemented with patient history and an electrocardiogram (ECG) (the extended algorithm) for predicti
Objectives: This study explores how different combinations of the number of diseases and experienced symptoms are related to life satisfaction in a population of 296 eighty-year-olds in southern Sweden. Methods: Three different models, visualizing different health profiles, in the form of reported number of diseases and number of experienced symptoms in different combinations were created and are
Most of field stars originate from dissolved star clusters. If the gas cloud is well mixed the stars in the cluster are expected to be chemically homogenous. Although the original kinematical information of a star may be lost under the Galactic dynamic evolution, the chemical signatures are preserved in the form of elemental abundances in individual low-mass stars. The present-day distribution of
Popular Abstract in English Life on earth has evolved countless forms, beautiful shapes and colors as well as astonishingly complex systems. Remarkably, all living creatures consist of cells, which themselves are build from the same basic set of molecules, most importantly nucleic acids (RNA and DNA), lipids and proteins. The latter are large macromolecules that fulfill a vast number of tasks; theThe three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. We used the Fold-and-Dock algorithm, which is part of the Rosetta macromolecular modeling suite, for de novo structure prediction of coiled-coil proteins. Members of this protein family
