Sökresultat

DMSO är ett vanligt lösningsmedel för studier av syntetiska molekyler i biologiska system, bl.a. inom läkemedelsutveckling. Trots detta är lösningsmedlets interaktioner med dessa syntetiska molekyler och deras målprotein inte tillräckligt undersökta. DMSO kan påverka proteinerna struktur eller ha någon annan inverkan inbindningen. I detta arbete har denna möjliga effekt studerats för inbindningen DMSO sees common application as a solvent for studies of synthetic molecules in biological systems, in fields such as drug design. Despite this, the possibility and nature of solvent interactions with both synthetic ligand and their target macromolecules is widely unexamined. DMSO could potentially have significant effect on binding characteristics due to conformational changes of protein structur

The growth of tissues and organs in plants is governed by the morphogen auxin coupled with the membrane protein PIN, which together generate patterns that guide development. Systems of this kind have been studied extensively in experiments and computational system biology models. This thesis builds on that work by introducing a stochastic version of these models to examine differences between stoc

Microfluidic applications nowadays have become of great interest due to their broad compatibility especially in biological applications, and one of them being droplet-based cell encapsulation. Cell encapsulation in droplets is carried out by discretising an aqueous phase (i.e. cell suspension) and including them into a continuous oil phase. This methodology is a potential gateway to high throughpu

Purpose: According to literature there is a set of six key competencies that distinguish sustainability professionals, including researchers, from professionals and researchers in other fields, making them “systemic problem solvers, change agents, and transition managers”. However, there is lack of empirical evidence, first, that these skills are necessary and sufficient for sustainability problem

Med en urban expansion världen över krävs det idag att biologisk mångfald räknas med vid utveckling av städer och omkringliggande ytor. I Ronneby kommun skall området Kilen omvandlas från att ha varit ett gammalt industriområde till att bli en ny stadsdel med bostäder, arbets- och handelsmöjligheter samt grönytor som kan fungera för rekreation och gynnande av biologisk mångfald. För utvecklingen a

Hur bör de senaste decenniernas utveckling inom IT och pedagogik påverka utformningen av nya lärandemiljöer? Kan skolarkitektur bidra till att främja god fysisk och psykisk hälsa? Arbetssätt och målsättningar har ändrats mycket inom den svenska skolan under de senaste decennierna. Informationsteknologi har i grunden ändrat tillgängligheten till information och påverkat hur vi både arbetar och koHow should the technological and pedagogical development during the last few decades affect the design of new schools? Can school architecture contribute to good physical and mental health in young teenagers? The way of working and targets for what the students should achieve have changed a lot in Sweden during the last few decades. Information technology has fundamentally changed the ease of ac

This thesis studies the application of Linear Predictive coding (LPC) in the downlink of Long Term Evolution (LTE) fronthaul, which comprises of BBU and RRH. This can act as an additional module in the existing system. Today, the transmission of a single complex sample from the BBU to the RRH consumes 30 bits. The research of the thesis is to analyze the application of linear prediction theory in

On the 23rd of June the British electorate chose to vote in favour of leaving the EU. The fact that one of the prominent states will leave the EU project is in itself controversial. This thesis examines the Leave campaign through a framing analysis. A qualitative method is used in order to identify the frames within publications made by the campaign, during April-June of 2016. The content of the f

The aim of this study was to examine municipalities local norms of financial support regarding housing costs, and to analyse the municipalities from a new institutional perspective, more specifically adaptation to national guidelines and their isomorphism. The study did not aim to examine or analyse individual social workers’ methods and reflections, but to analyse the municipalities local guideli

I uppsatsen undersöker jag hur begrepp och teori från visuell kultur kan användas för att analysera arkitektur och i synnerhet hem genom att utforma ett analysverktyg för bilder. Syftet är att undersöka hur föreställningar, värderingar och idéer hos betraktare kan påverkas av det som bilderna förmedlar, och vilken makt bildproducenter av bilder på arkitektur har som individer och grupper. Jag är s

This thesis has been made in collaboration with the company Orbital Systems. The aim has been to optimize their product the Orbital shower, which is a circulating shower system. The work evaluates different sensor techniques suitable for detection of contaminants in greywater. After a comprehensive literature study, three techniques; ultrasound, IR and impedance were further investigated and prac

This thesis aims to provide information regarding which critical success factors that are beneficial for small and medium enterprises when implementing Robotic Process Automation. It has been done by identifying 11 critical success factors from 14 academic research articles treating Critical Success Factor’s in Customer Relationship Management and Enterprise Resource Planner implementations. The 1

Bakgrund: Hundar används inom många områden i hälso- och sjukvården, för att bland annat motivera, aktivera eller möjliggöra för klienten att utföra och delta i aktiviteter mer självständigt. Arbetsterapeutisk forskning har visat att utförande av aktiviteter som upplevs som meningsfulla för människan och där hon känner delaktighet i samhället har samband med både välbefinnande och bättre hälsa. Mo

Thesis Purpose: The aim of this research project was to uncover the meaning of extraordinary experiences for consumers’ identity projects and to understand how extraordinary experiences, rather than brands and possessions, can be used for self-presentation and self-extension. Methodology: Following Van Manen’s method for hermeneutic phenomenological research combined with Derrida’s notion of deco

The aim of this study was to examine students gaming habits and what function playing computer games fulfil for students. The study was conducted with the help of a survey methodology and was sent to 500 students at Lunds university. The students got selected via an unbound random selection. 52 participants answered the survey. They majority of students plays computer games. Regarding those who pl

The major problem when developing primers and probe sets for detection of HIV-1 is its high genetic variability and strong ability to mutate. HIV-1 is divided into four groups, M, N, O, P based on genetic similarities, and there are more than 70 different circulating recombinant forms. The aim of this master thesis was to develop new primers and probe for a novel quantitative PCR analysis method f

This thesis investigates methods that estimate the Expected Shortfall correctly by passing the Acerbi-Szekely (2014) backtest in both stressed and calm periods. This backtest is added to in this thesis to test against both under- and overestimation of ES. This research is relevant due to the recent shift in the Basel’s Fundamental Review of the Trading Book from using Value-at-Risk as the leading

To utilize sugars as a feedstock for renewable industries, the feedstock often needs to be very pure. This is due to ionic species contaminating the sugar feedstock being potent catalyst poisons in many cases. To remove ionic species from the sugar feedstock, it is dissolved and purified using packed ion-exchange columns. In this report, a lab-scale setup of a large scale ion-exchange setup was co

The main challenge to future scenario construction is to help people see themselves as part of a larger system in a way that empowers them rather than reinforces the belief they are helpless. This thesis aims to overcome this challenge by investigating what can be learned from the Japanese tradition of repair called Kintsugi and the underlying Wabi-Sabi philosophy. Subsequently, the research explo