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Randomized controlled trials (RCTs) of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS) have produced outcomes varying from no effect at all to high efficacy and durable effects over time. This review analyzed differences in the protocols used in FMT RCTs for IBS in the recently published literature with the aim of identifying the factors responsible for the s
Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin-dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's characteristics. Glucuronidases (EC 3.2.1.139) and xylan α-1,2-gl
Digital transformations have significant consequences for organizational attempts to shape their environments. Our focus is on how corporate political activity evolves in ways that require us to pay more attention to how information gets structured in digital spaces, and on how information ecosystems operate and shape strategic communication activities in organizational settings. We outline these
The automation of map labeling is an ongoing research challenge. Currently, the map labeling algorithms are based on rules defined by experts for optimizing the placement of the text labels on maps. In this paper, we investigate the feasibility of using well-labeled map samples as a source of knowledge for automating the labeling process. The basic idea is to train deep learning models, specifical
Welfare capitalism has developed in the context of rapidly expanding, fossil fuel-driven industrial economies. Faced with the urgent need for systematic changes of economic systems so that they stay within planetary limits, decoupling welfare from economic growth is an important task. This chapter introduces the concept of sustainable welfare, referring to welfare systems that prioritise the satis
Implantable cell replacement therapies promise to completely restore the function of neural structures, possibly changing how we currently perceive the onset of neurodegenerative diseases. One of the major clinical hurdles for the routine implementation of stem cell therapies is poor cell retention and survival, demanding the need to better understand these mechanisms while providing precise and s
Driving automation systems, including autonomous driving and advanced driver assistance, are an important safety-critical domain. Such systems often incorporate perception systems that use machine learning to analyze the vehicle environment. We explore new or differing topics and challenges experienced by practitioners in this domain, which relate to requirements engineering (RE), quality, and sys
In this introductory article, we explain the purpose of this special issue that is set up as a Festschrift in honour of the (editorial) work of BengtJohannisson. Inspired by Italo Calvino's Six Memos for the Next Millennium, the special issue is structured along six essays that are both commemorative and affirmative, that is we use the work of Johannisson to explore fresh waters and invent new pra
Many concepts for future generations of wireless communication systems use coherent processing of signals from many distributed antennas. The aim is to improve communication reliability, capacity, and energy efficiency and provide possibilities for new applications through integrated communication and sensing. The large bandwidths available in the higher bands have inspired much work regarding sen
Gaze-control and gaze-assistance in software development tools have so far been explored in the setting of code editing, but other developer activities like code review could also benefit from this kind of tool support.In this paper, we present GANDER, a platform for user studies on gaze-assisted code review. As a proof of concept, we extend the platform with an assistant that highlights name rela
The biogenesis of transfer RNA is a process that requires many different factors. In this study, we describe a genetic screen aimed to identify gene products participating in this process. By screening for mutations lethal in combination with a sup61-T47:2C allele, coding for a mutant form of, the nonessential TAN1 gene was identified. We show that the TAN1 gene product is required for formation o
The purpose of this paper is to show how requirements engineering techniques can be used to structure the development of non-technical aspects of socio-technical systems, such as guidelines. An adapted requirements engineering approach was chosen to elicit requirements for resilience guidelines within an EU Horizon 2020 multi-national project aimed at developing resilience guidelines for crisis ma
Managing complexity and uncertainty in high-risk sociotechnical systems requires people to continuously adapt. Designing resilient systems that support adaptive behavior requires a deepened understanding of the context in which adaptations take place, of conditions and enablers to implement these adaptations, and of their effects on the overall system. Also, it requires
History shows that wars can be enormously disruptive of economic activity, especially international trade, national income, and global economic welfare. This article analyzes the impact on the European regions the Russian invasion of Ukraine using the largest and most updated multiregional input-output model for Europe. Two shocks, trade and inflation, and four alternative scenarios are simulated.
This paper presents a simple and effective control solution to regulate temperature and humidity inside a greenhouse, which are the main climatic variables affecting crop growth and health. A multivariable control strategy with inverted decoupling is proposed in two schemes. The nighttime control scheme uses heating and dehumidification, and the daytime control scheme uses natural ventilation, deh
