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The SPECIES beamline at the MAX IV Laboratory : A facility for soft X-ray RIXS and APXPS

SPECIES is an undulator-based soft X-ray beamline that replaced the old I511 beamline at the MAX II storage ring. SPECIES is aimed at high-resolution ambient-pressure X-ray photoelectron spectroscopy (APXPS), near-edge X-ray absorption fine-structure (NEXAFS), X-ray emission spectroscopy (XES) and resonant inelastic X-ray scattering (RIXS) experiments. The beamline has two branches that use a comm

Composition and structure of high temperature dairy fouling

The fouling structure and composition is dependent on the product, but also on the heating process applied to it. The structure will have profound effect on the cleaning process and the down time in the production plant. Here, the structure of high temperature (137 °C) milk fouling has been investigated, which so far has not been sufficiently studied in a systematic way. This particular fouling ha

Low-frequency and common genetic variation in ischemic stroke : The METASTROKE collaboration

OBJECTIVE: To investigate the influence of common and low-frequency genetic variants on the risk of ischemic stroke (all IS) and etiologic stroke subtypes.METHODS: We meta-analyzed 12 individual genome-wide association studies comprising 10,307 cases and 19,326 controls imputed to the 1000 Genomes (1 KG) phase I reference panel. We selected variants showing the highest degree of association (p < 1

Electrical Characterization and Modeling of Gate-Last Vertical InAs Nanowire MOSFETs on Si

Vertical InAs nanowire transistors are fabricated on Si using a gate-last method, allowing for lithography-based control of the vertical gate length. The best devices combine good ON- and OFF-performance, exhibiting an ON-current of 0.14 mA/μm, and a sub-threshold swing of 90 mV/dec at 190 nm LG. The device with the highest transconductance shows a peak value of 1.6 mS/μm. From RF measurements, th

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma

We performed a multistage genome-wide association study of melanoma. In a discovery cohort of 1804 melanoma cases and 1026 controls, we identified loci at chromosomes 15q13.1 (HERC2/OCA2 region) and 16q24.3 (MC1R) regions that reached genome-wide significance within this study and also found strong evidence for genetic effects on susceptibility to melanoma from markers on chromosome 9p21.3 in the

BRCA2 gene mutations and coagulation-associated biomarkers

Thromboembolic events are the second cause of death in cancer patients, although the mechanisms underlying this increased thromboembolic risk remain unclear. The aims of this study were to examine whether BRCA2 gene mutations may modify the circulating levels of thrombocoagulation biomarkers and whether breast cancer development may influence changes in such circulating biomarkers. The study was p

Life course perspectives on economic stress and generalized trust in other people

The aim is to investigate the associations between economic stress in childhood and adulthood, and low generalized trust in other people, testing two life course hypotheses. The 2008 public health survey in Scania is a cross-sectional postal/mail questionnaire study in which 28,198 persons aged 18-80 participated (55% participation in the original sample). Logistic regressions were used to analyze

Association between shift work history and performance on the trail making test in middle-aged and elderly humans : The EpiHealth study

Shift work has been proposed to promote cognitive disturbances in humans; however, conflicting evidence is also present. By using data from 7143 middle-aged and elderly humans (45-75 years) who participated in the Swedish EpiHealth cohort study, the present analysis sought to investigate whether self-reported shift work history would be associated with performance on the trail making test (TMT). T

Characterization of antioxidant polyphenols from Myrciaria jaboticaba peel and their effects on glucose metabolism and antioxidant status : A pilot clinical study

Brazilian berries, such as Myrciaria jaboticaba (jaboticaba), are good sources of polyphenols with a recognized function in oxidative stress attenuation proved in non-clinical studies. In the present study, the polyphenols profile and their contribution to the antioxidant capacity of the jaboticaba peel were analyzed using high-performance liquid chromatography (HPLC) with photodiode array (DAD),

Dynamic capabilities in disaster management exercises

This paper introduces the concept of 'dynamic capability' (DC) in relation to disaster management - in particular to disaster management exercises (DME). Firstly this paper discusses changes and challenges in DME and the concept of dynamic capabilities as one potential approach dealing with the existing challenges in DME. Thereafter it outlines basic contents of developing DC in DME. The paper con

Recent hip fracture trends in Sweden and Denmark with age-period-cohort effects

Summary: This study used nationwide hip fracture data from Denmark and Sweden during 1987–2010 to examine effects of (birth) cohort and period. We found that time trends, cohort, and period effects were different in the two countries. Results also indicated that hip fracture rates may increase in the not so far future. Introduction: The reasons for the downturn in hip fracture rates remain largely

Pain Sensitivity and its Relation to Spreading on the body, Intensity, Frequency, and Duration of Pain : A Cross-sectional Population-based Study (SwePain)

OBJECTIVES:: Individuals with chronic pain often report increased pain sensitivity compared to pain free individuals, so it is crucial to determine if and how different pain characteristics influence or interact with pain sensitivity. An alternative to experimental pain sensitivity testing is the self-reported pain sensitivity questionnaire (PSQ), that captures pain sensitivity in various body are

Incidence of oral thrush in patients with COPD prescribed inhaled corticosteroids : Effect of drug, dose, and device

Background and aims Little information is available on real-life occurrence of oral thrush in COPD patients treated with ICS. We investigated oral thrush incidence in COPD patients prescribed FDC ICS/LABA therapies and assessed whether it is modulated by the ICS type, dose, and delivery device. Methods We conducted a historical, observational, matched cohort study (one baseline year before and one

Maximise your returns in crisis management preparedness : A cyclic approach to training and exercises

Training and exercises programmes are not independent activities, forming part of a larger, risk-based, process of disaster management preparedness. In order to have an impact on an individual's skills knowledge or behaviours, or to influence organizational learning or procedures, the programmes needs a cyclic and holistic approach. It should focus on clearly identified outcomes that are designed

Individualized prediction of lung-function decline in chronic obstructive pulmonary disease

Background: The rate of lung-function decline in chronic obstructive pulmonary disease (COPD) varies substantially among individuals. We sought to develop and validate an individualized prediction model for forced expiratory volume at 1 second (FEV1) in current smokers with mild-to-moderate COPD. Methods: Using data from a large long-term clinical trial (the Lung Health Study), we derived mixed-ef

Gender, anthropometric factors and risk of colorectal cancer with particular reference to tumour location and TNM stage : A cohort study

Background: It remains unclear whether the increased risk of colorectal cancer (CRC) associated with obesity differs by gender, distribution of fat, tumour location and clinical (TNM) stage. The primary aim of this study was to examine these associations in 584 incident colorectal cancer cases from a Swedish prospective population-based cohort including 28098 men and women. Methods: Seven anthropo

Three-dimensional functional human neuronal networks in uncompressed low-density electrospun fiber scaffolds

We demonstrate an artificial three-dimensional (3D) electrical active human neuronal network system, by the growth of brain neural progenitors in highly porous low density electrospun poly-ε-caprolactone (PCL) fiber scaffolds. In neuroscience research cell-based assays are important experimental instruments for studying neuronal function in health and disease. Traditional cell culture at 2D-surfac