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This study aims to investigate the possibility of implementing serial autoradiography using a silicon strip detector as an imaging modality in pre-clinical radionuclide therapy research, in order to study the effect of non-uniform uptake on absorbed dose distribution and biological response. Tumor tissues expressing CD20 (B-cell lymphoma) or carcinoembryonic antigen (CEA; colorectal cancer) were e
Chemiluminescent (CL) enzyme-based flow-through microchip biosensors (mu-biosensors) for detection of glucose and ethanol were developed for the purpose of monitoring real-time production and release of glucose and ethanol from microchip immobilised yeast cells. Part I of this study focuses on the development and optimisation of the mu-biosensors in a microfluidic sequential injection analysis (mu
Popular Abstract in Swedish I Sverige bestäms fastighetsgränsers sträckningar i första hand av gränsmärken på marken, därefter av förrättningskartor och mätuppgifter. Under senare år har efterfrågan på digital fastighetsinformation ökat kraftigt, inte minst beträffande lägesnoggranna gränsdata i den nationella registerkartan. Den utvecklade positioneringstekniken med GPS utgör idag en grundförutsäIn Sweden, the course of a property boundary is first and foremost determined by boundary marks on the ground, and only secondly by cadastral survey plans and measurements. In recent years, the demand for digital property information has increased substantially, not least in respect of accurate boundary data in the national cadastral map. Today, well-established techniques such as GPS positioning
The present thesis addresses three issues related to proteinaceous films at solid/liquid interfaces: adsorption, lubrication and enzymatic interactions. Most of the work has been devoted to oral systems. In addition, gelatin has been investigated as a model protein. Salivary protein adsorption from human whole saliva (HWS) onto hydroxyapatite (HA) and silica has been characterised using ellipsome
Liberalisation and deregulation of public utility sectors has been introduced in several European countries. In 1994 Swedish municipalities were instructed to reorganise waste collection routines by enlarging the number of fractions to be able to reuse waste fractions in an environmental benign way. The public waste sector have to a considerable extent been diversified and deregulated. At the same
Popular Abstract in Swedish Proteiner är en av kroppens viktigaste beståndsdelar. Proteiner bygger upp stabila nätverk för att cellerna ska ha sin rätta form, de transporterar in vatten, salt och andra molekyler in i cellerna så att vi kan ta upp näring och de katalyserar kemiska reaktioner. Proteiner är uppbyggda av aminosyror som binds ihop till en kedja och som sedan veckar ihop sig så att protSeveral neurodegenerative diseases are caused by peptides or proteins forming amyloid fibrils such as the Aβ peptide involved in Alzheimer’s disease and the huntingtin exon-1 with a prolonged polyglutamine (polyQ) stretch involved in Huntington’s disease. The ability to form amyloid fibrils is an intrinsic feature in all proteins. The fibrils are built up of monomers to form elongated structures w
Popular Abstract in Swedish Den vanligaste dödsorsaken i västvärlden är hjärt-kärlsjukdom. Därför finns det ett stort intresse att undersöka vilka faktorer som är av avgörande betydelse för att vi ska utveckla t.ex ateroskleros (åderförkalkning). Spelar livsstil och matvanor någon roll eller är det helt och hållet genetiskt betingat? Utvecklingen av förebyggande åtgärder, operationsteknik och post
The objectives of this dissertation are 1) to describe what child protection services actually do when assessing risk and deciding on interventions, and 2) to analyze this practice in the light of institutional expectations, organizational demands and professional technology. The field work was carried out in two Danish municipal social service agencies. Data consist of records on families subject
1. Quantitative reconstruction of past vegetation distribution and abundance from sedimentary pollen records provides an important baseline for understanding long term ecosystem dynamics and for the calibration of earth system process models such as regional-scale climate models, widely used to predict future environmental change. Most current approaches assume that the amount of pollen produced b
Water-based copolymer dispersions were prepared using methyl methacrylate (MMA), ethyl acrylate (EA) (MMA/EA = 1:2), and a series of nonionic polymerizable surfactants, i.e., "surfmers" based on poly(ethylene glycol)-(meth)acrylates. The latexes were compared with the behavior of a conventionally stabilized (nonionic nonylphenol ethoxylate, NP100 with 84 ethylene oxide units) dispersion with the s
Aim: Colorectal cancer is the third most common form of cancer in the industrial countries. Due to advances regarding the treatments, primarily development of improved surgical methods and the ability to make the earlier diagnosis, the mortality has remained constant during the past decades even though the incidence in fact has increased. To improve chemotherapy and enable personalised treatment,
Can an educational programme develop tomorrow’s leaders? Can the mindset and skill set found in successful leaders be taught and learnt in educational programmes? This paper presents a leadership program, a cross disciplinary master programme atLund University, Sweden. The students study technology and management, however, the programme’s unique value proposition lies in its focus on leadership.Th
This paper presents simulation results for a sliding-IF SiGe E-band transmitter circuit for the 81-86 GHz E-band. The circuit was designed in a SiGe process with fT = 200 GHz and uses a supply of 1.5 V. The low supply voltage eliminates the need for a dedicated transmitter voltage regulator. The carrier generation is based on a 28 GHz quadrature voltage oscillator (QVCO). Upconversion to 84 GHz is
Popular Abstract in Swedish Grundvatten, det vatten som förekommer i hålrum i underjorden, är en av våra allra viktigaste naturresurser. Grundvattnet utgör den absolut största andelen för oss tillgängligt färskvatten och används för att producera mat och som processvatten inom olika industrier. Ungefär hälften av jordens dricksvattenförsörjning baseras på grundvattenuttag och ekosystem världen övePesticides are known to occur in groundwater worldwide. However, long-term pollution concerns and cause-effect relationships for specific regions remain limited. This thesis explores the occurrence of pesticides in south-Swedish groundwater, with the aims of providing a better knowledge basis for assessment and management of present-day and future pollution risks. The investigations are restricted
In order to explore verbal-nonverbal integration, we investigated the influence of cognitive and linguistic ability on gaze behavior during spoken language conversation between children with mild-to-moderate hearing impairment (HI) and normal-hearing (NH) peers. Ten HI-NH and 10 NH-NH dyads performed a referential communication task requiring description of faces. During task performance, eye move
Rainflow cycles are often used in fatigue analysis of materials for describing the variability of applied loads. Therefore, an important characteristic of a random load process is the intensity of rainflow cycles, also called the expected rainflow matrix (RFM), which can be used for evaluation of the fatigue life. In this thesis mainly two problems are addressed: the first is computation of the ex
Telephone service in Argentina has since its beginning been characterized as one of the most developed in South America. Regarding its development, two distinct periods can be identified. An initial period of private ownership extended from 1878 to 1946. In 1946, when the largest telephone company was bought by the state, a period of predominant state-ownership began that lasted until 1990 when th
Syftet med uppsatsen är att, ur ett rättshistoriskt perspektiv, granska hur erkännandet som bevismedel hanterats och värderats i den historiska rättsprocessen med fokus på processen I brottmål. I centrum för analysen står erkännandets innebörd och bevisvärde i förhållande till de bevisrättsliga principerna legal bevisteori respektive fri bevisvärdering. Ingående utreds också hur övriga historiska The purpose of this paper is to critically review the confession as evidence in a legal and historical perspective by looking at how it has been handled and valued historically in the lawsuit, focusing on the criminal process. The core of the analysis comprises the meaning of the confession and its value as evidence in relation to the procedural principles; the legal proof theory and the principle
