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Background: Research involving expressed sequence tags ( ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and satisfactory annotated public sequence libraries are, however, available only for a limited range of organisms, rendering the absence of sequences and gene structure information a tangible problem for those working with ta
Popular Abstract in Swedish Kroppens immunförsvar, vars uppgift är att skydda oss mot infektioner, består av ett antal olika celltyper som till stor del finns i blodet. Immunförsvaret kan indelas i två delar; ett medfött försvar som är likadant hos alla individer och ett försvar som byggs upp under individens livstid. Det senare utformas olika beroende på vilka bakterier och virus som individen utThe cells of the innate immune system are essential for the host's first line defence against infection. Among these cells the neutrophil granulocyte has a central role by the production of antibiotic proteins and peptides. These are targeted for storage in secretory lysosomes and other neutrophil granules for subsequent release by regulated secretion in an inflammatory process. However, the granu
In a warming climate, permafrost is likely to be significantly reduced and eventually disappear from the sub-Arctic region. This will affect people at a range of scales, from locally by slumping of buildings and roads to globally as melting of permafrost will most likely increase the emissions of the powerful greenhouse gas methane, which will further enhance global warming. In order to predict fu
The objective of this thesis is to propose a way to introduce social and cultural aspects of environmental degradation to the sustainable development debate. This is done by a reflexive and critical examination of environmental research as it has been applied to different spatial levels (and thus levels of social complexity). The spatial categories discussed are the city, the household and the lan
The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. If too many leukocytes are recruited, normal, not injured, cells can be damaged; a process known from chronic inflammatory diseases such as reumatoid arthritis,
Popular Abstract in English Airborne particulate matter is well known because of its adverse impacts on human health and its role in climate processes. In order to understand completely the role of aerosols in atmosphere, their chemical composition is of basic importance. Chemical analysis of aerosols involves broadly two steps, extraction step and detection/quantification of chemical constituents
Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. It is thought that VHb facilitates oxygen delivery to the respiratory apparatus of its host by increasing the local oxygen concentration under oxygen-
The main purpose of this thesis was to examine various factors influencing starch retrogradation. The reassociation events of starch, which are closely linked to the staling of bakery products, were mainly studied by thermal analysis. Some aspects of starch gelatinization are also included. The gelatinization and retrogradation were described as non-equilibrium processes where the phase transition
Nerve fibres play an important role in the regulation of gastric emptying. The aims of this study were to clarify the distribution, projections and origin of neuronal type nitric oxide synthase (NOS)-, tyrosine hydroxylase (TH)-, vesicular acetylcholine transporter (VAchT)- and peptide-containing nerve fibres of the rat pyloric sphincter. Extrinsic and local denervations of the sphincter were perf
Background: The aim of this study was to explore the feasibility of using a technique based on artificial neural networks for quality assurance of image reporting. The networks were used to identify potentially suboptimal or erroneous interpretations of myocardial perfusion scintigrams (MPS). Methods: Reversible perfusion defects (ischaemia) in each of five myocardial regions, as interpreted by on
This paper presents a front-end architecture for fully integrated 60 GHz phased array receivers. It employs LO-path beamforming using a phase controlled phase-locked loop (PC-PLL). To demonstrate the architecture a circuit is implemented featuring a two stage low noise amplifier, two cascaded active mixers, and a PC-PLL. The receiver downconverts the 60 GHz signal in two steps, using LO signals fr
In an era of lifelong learning, empowerment of the learner becomes fundamental. Therefore ex-ploitation of the full potential of learning objects depends upon creation of an appropriate infra-structure to promote symmetrical control of inquiry. The learner needs to be empowered because learning is a discovery process and thus must be under his or her own control. In early stages of education it
Popular Abstract in Swedish Avhandlingen omfattar förutom en kort inledning, i huvudsak två delar: (1) Beskrivning av teorin bakom ett datorbaserat verktyg för simulering av termodynamiken i ett motorsystem, där främst motorer med Homogen Kompressionsantändning (Homogeneous Charge Compression Ignition, HCCI) avses. Med system avses förutom själva motorn, turboladdare, laddluftkylare, insug och avgThis thesis focuses on engine system simulation using thermodynamics and chemical kinetic models to investigate the performance and efficiency of Homogeneous Charge Compression Ignition (HCCI) engines for stationary applications. It includes the development of software as well as models for engine, turbocharger, intercooler, inlet and exhaust manifolds, wastegate valve, inlet air humidifier, inle
Popular Abstract in Swedish Eftersom politiska partier är kollektiva varor står potentiella partibildare inför det kollektiva handlandets problem. Därför kan vi tala om en "partibildningsparadox". Sålunda är det förvånande att icke riksdagsetablerade partier blev vanligare förekommande i svenska kommuner mellan 1973 och 2002. Utvecklingen ger oss ett unikt material på vilket vi kan pröva hypoteserSince political parties are collective goods, groups of people that demand new political parties face a collective action problem. Therefore, we can speak of a ?paradox of party-emergence?. Hence, it is puzzling that new parties became increasingly common in representative bodies at the Swedish local level during 1973?2002. This development provides a unique circumstance on which to test hypothese
Objective: The aims were to evaluate the frequency and nature of errors in medication when patients are transferred between primary and secondary care. Method: Elderly primary health care patients (> 65 years) living in nursing homes or in their own homes with care provided by the community nursing system, had been admitted to one of two hospitals in southern Sweden, one university hospital and on
Popular Abstract in Swedish Denna doktorsavhandling i ämnet pedagogik utgör en analys av effekter av den pågående kulturella globaliseringen genom att granska två internationella magisterprogram vid Lunds universitet. Studiens syfte är att spåra mönster i en bärande pedagogisk idé för överföring av ett interkulturellt tänkande i tvärkulturella möten genom att utforska, beskriva och försöka förstå The present study is designed to analyze the effects of the ongoing cultural globalization. It utilizes as its empirical setting two special programmes called the International Master's Programme (the IMP,) directed by Lund University in Sweden. The aim of the study is to infer a pedagogic idea for intercultural transmission through cross-cultural encounters by exploring, describing, and comprehen
This paper addresses the question of why metal- deficient barium stars are not yellow symbiotic stars ( YSyS). Samples of ( suspected) metal-deficient barium ( mdBa) stars and YSyS have been collected from the literature, and their properties reviewed. It appears in particular that the barium nature of the suspected mdBa stars needs to be ascertained by detailed abundance analyses. Abundances are
Popular Abstract in Swedish Den nuvarande teknologin inom förbränningsmotorer har möjligheten att hantera den alltmer strikta myndighetskraven på förbränningsmotorn. Emellertid de nödvändiga tekniska lösningarna som krävs är dyra och alltmer tekniskt krävande. En möjlig väg mot enklare efterbehandlingssystem är anvädningen av Homogen Kompressions Antändning (Eng: HCCI) motor cykeln. Den huvudsaklThe current technology within combustion engines have the possibility of handling the more stringent legislative demands on combustion engines. However the required solutions are getting more expensive and technically challenging. One possible way towards a more simple exhaust aftertreatment system is the use of the Homogeneous Charge Compression Ignition (HCCI) engine cycle. The main advantage o
With the attempts to achieve higher thermal efficiency, turbine blades are exposed to very high temperature gases and may undergo severe thermal stress and fatigue. Thus, in order to develop optimal cooling strategies and reduce the heat transfer it is important to obtain a good understanding of both the complex flow field and the heat transfer characteristics in turbine rotor/stator hot-gas passa
