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Amyloid formation is linked to devastating neurodegenerative diseases, motivating detailed studies of the mechanisms of amyloid formation. For Aβ, the peptide associated with Alzheimer’s disease, the mechanism and rate of aggregation have been established for a range of variants and conditions in vitro and in bodily fluids. A key outstanding question is how the relative stabilities of monomers, fi
The present study evaluates the effect of water and acetic acid washing on the chemical composition of spruce bark in-depth. Also, washing with steam explosion condensate (SEC) was investigated which is a novel attempt. The leaching kinetics of troubling elements (TE) was studied to understand the leaching behavior of TEs and for upscaling the process. Furthermore, to study the ash transformation
As a fuel for power generation, high-pressure hydrogen gas is widely used for transportation, and its efficient storage promotes the development of fuel cell vehicles (FCVs). However, as the filling process takes such a short time, the maximum temperature in the storage tank usually undergoes a rapid increase, which has become a thorny problem and poses great technical challenges to the steady ope
The Earth’s magnetic field (or geomagnetic field) has been measured for hundreds of years, starting with maritime observations from logbooks for navigation purposes to present day real-time recording by satellites. From these records, the geomagnetic field variation throughout recent time is well-understood. In order to study longer term field variations (on the scale of hundreds to thousands of y
The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood, a problem that is exacerbated by the enormous genetic heterogeneity of this disease group. However, the last decade has yielded a wealth of new knowledge on degenerative pathways and their diversity. Notably, a central role of cGMP-signalling has surfaced for photoreceptor cell death triggered by
Olfactory dysfunction is a common feature of both postviral upper respiratory tract infections (PV) and idiopathic Parkinson’s disease (PD). Our aim was to investigate potential differences in the connectivity of the posterior piriform cortex, a major component of the olfactory cortex, between PV and PD patients. Fifteen healthy controls (median age 66 years, 9 men), 15 PV (median age 63 years, 7
Life Cycle Assessment (LCA) studies are valuable tools for identifying high impact processes and redesigning supply chains. However, LCAs have limits, in the sense that they offer insight into relative sustainability and don't question whether a product, or its use, is sustainable in absolute terms. In this intentionally provocative paper, you join Emma, a fictional average American 15-year-old, a
In banana cultivation, a considerable amount of the production is wasted every year because of various constraints present in the post-harvest management chain. Converting green banana pulp and peels into flour could help to reduce losses and enable the food sector to keep the product for an entire year or more. In order to use green banana fruit and peel flour in the food industry as a raw ingred
The aim of this study was an in-depth investigation of the change process experienced by patients undergoing bariatric surgery. A prospective interview study was performed prior to as well as 1 and 2 years after surgery. Data analyses of the transcribed interviews were performed by means of the Grounded Theory method. A core category was identified: Wishing for deburdening through a sustainable co
A number of deleterious health effects have been identified from exposure to outdoor airborne particulate matter. Given that in developed countries we spend majority of our time indoors, in private homes about 65 % (Brashe et al., 2005), the understanding of this exposure is important, yet knowledge is sparse. Particle levels indoors are affected by indoor sources, infiltration from outdoors or pa
The anaerobic bacterium Finegoldia magna is part of the human commensal microbiota, but is also an important opportunistic pathogen. This bacterium expresses a subtilisin-like serine-proteinase, SufA, which partially degrade the antibacterial chemokine MIG/CXCL9. Here, we show that MIG/CXCL9 is produced by human keratinocytes in response to inflammatory stimuli. In contrast to the virulent human p
The observation that neural grafts can induce dyskinesias has severely hindered the development of a transplantation therapy for Parkinson's disease (PD). We addressed the hypothesis that inflammatory responses within and around an intrastriatal graft containing dopamine neurons can trigger dyskinetic behaviors. We subjected rats to unilateral nigrostriatal lesions with 6-hydroxydopamine (6-OHDA)
Popular Abstract in Swedish Vanlig bagerijäst, Saccharomyces cerevisiae, används i storskalig etanol framställning från majs och sockerrör. Användandet av dessa råvaror för etanolproduktion konkurerar dock med framställning av spannmål för föda och djurhushållning. Den här avhandlingen har syftat till att få bagerijäst att använda sockerarten xylos, som finns i stora halter i restprodukter från skBaker’s yeast, Saccharomyces cerevisae, has been engineered to utilize the pentose sugar xylose present in lignocellulose biomass for the production of ethanol. Currently ethanol production from xylose is slow which limits the implementation of said strains in industrial production. This thesis describes the investigation of several metabolic aspects that control the rate of xylose utilization by
Aims and objectives: The research presented investigates older people’s expectations of social assistive robots and telehealthcare systems. Methods: The empirical studies presented are based on fieldwork carried out before social assistive robots and a telehealthcare system were introduced into the domestic environment of older people. The research draws upon participatory design to explore older
Wind power is seen by many observers as an important part of the transition to a sustainable energy system, since it does not contribute to the environmental problems connected with dominating energy forms such as fossil fuel, nuclear power and large-scale hydro power. At the same time wind power has some characteristics that makes it a special challenge for land use planning. In Sweden, where win
During the stress response adrenal medullary chromaffin cells release catecholamines to the bloodstream. Voltage-activated calcium channels present in the cell membrane play a crucial role in this process. Although the electrophysiological and pharmacological properties of chromaffin cell calcium channels have been studied in detail, the molecular composition of these channels has not been defined
A new spectrometer for studying photoinduced fragmentation has been designed and commissioned. The instrument produces a detailed view of the energy and angular emission of fragments, which in the case of small molecules can be related to their geometry at the moment of dissociation. The spectral profiles for single, double and triple ion coincidences are analyzed in terms of molecular alignment,
Vad är överturism? En kunskapsöversikt CECILIA CASSINGER OCH JAN HENRIK NILSSON SAMHÄLLSVETENSKAPLIG FAKULTETEN | LUNDS UNIVERSITET 2 VAD ÄR ÖVERTURISM? Omslagsbild: Elizeu Dias on Unsplash Copyright: Cecilia Cassinger och Jan Henrik Nilsson Samhällsvetenskaplig fakulteten | Institutionen för strategisk kommunikation och Institutionen för service management och tjänstevetenskap | Lunds universitet
https://www.isk.lu.se/sites/isk.lu.se/files/web_overturism_nr5.pdf - 2026-07-16
Med en krympande industriell arbetsstyrka och den snabba utvecklingen inom artificiell intelligens, börjar många företag rikta blickarna mot intelligenta humanoida robotar för att understödja dem i deras verksamhet. Denna uppsats utforskar dagens landskap av humanoida robotar och skisserar hur Saab Naval kan påbörja processen av att integrera dem i deras skeppsvarvsproduktion. Nya framsteg och nuvWith a shrinking industrial workforce and the rapid advancement of artificial intelligence, many companies are starting to look toward intelligent humanoid robots to aid them in their operations. This thesis explores the current landscape of industrial humanoid robots and outlines how Saab Naval can start the process of integrating them into their shipyard production. Recent advancements and curre
This thesis investigates how cooperative membership impacts on the well-being of the individual. The case of the umbrella cooperative El Ceibo, operating in Bolivia, is investigated. Organizations such as the UN, the World Bank, and the ILO have high hopes for agricultural cooperatives as partners in the struggle for rural development. However, there is a lack of empirical studies investigating th
