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Purpose: Glucose concentrations are elevated in retinal cells in undiagnosed and in undertreated diabetes. Studies of diabetic patients suggest that retinal function adapts, to some extent, to this increased supply of glucose. The aim of the present study was to examine such adaptation in a model of type 2 diabetes and assess how the retina responds to the subsequent institution of glycemic contro
This contribution concerns the development of generic methods and tools for robust optimal control of high-pressure liquid chromatographic separation processes. The proposed methodology exploits a deterministic robust formulation, that employs a linearization of the uncertainty set, based on Lyapunov differential equations to generate optimal elution trajectories in the presence of uncertainty. Co
Video-on-Demand (VoD) and video sharing services account for a large percentage of the total downstream Internet traffic. In order to provide a better understanding of the load on these services, we analyze and model a workload trace from a VoD service provided by a major Swedish TV broadcaster. The trace contains over half a million requests generated by more than 20000 unique users. Among other
Sweden is part of a small European minority in the perceived societal gain of PPP. After a pilot PPP project in late 1990’s no additional project has been started in Sweden. Although there is interest from both public infrastructure clients and construction companies the national government has very clearly stated that infrastructure projects should be procured in a traditional way where all fundi
The HOO radical is a key intermediate in the atmosphere and is involved in a large number of reactions, including ozone loss cycles in the stratosphere and oxidation processes in the troposphere. This theses is a study of the HOO radical and its interactions with a number of small molecules that are present in the atmosphere. The HOO complexes were formed on the surface of growing argon matrices
A major challenge when designing general purpose graphics hardware is to allow efficient access to texture data. Although different rendering paradigms vary with respect to their data access patterns, there is no flexibility when it comes to data caching provided by the graphics architecture. In this paper we focus on volume ray-casting, and show the benefits of algorithm-aware data caching. Our M
Popular Abstract in Swedish Företagen har mer och mer problem att generera och utveckla kunskaper i samarbete med andra, enskilda företag. Forskare inom det teoretiska område kooperativ inlärning har börjat att undersöka hur partnerorganisationer lär sig att samarbeta med varandra. Men det specifika inlärningsinnehållet av denna kollektivt inlärda kunskap är generellt inte något de fokuserar på. DBusiness organizations increasingly face the problem of how to generate and share knowledge in collaboration with other, separate, business organizations. Researchers in the field of inter-organizational learning have started to study the partner-characteristic, partner-dynamic, and partner-situational factors that influence the process and outcome of such strategic learning collaboration. However
This paper investigates how river privatisation in Turkey is deployed to expand renewable energy production and the implications this has for issues of ownership, rights to water and community life. Recent neoliberal reforms in Turkey have enabled the private sector to lease the rights to rivers for 49 years for the sole purpose of electricity production. The paper focuses on the re-scaling and re
As the most figurative asset of membership in a majority or minority and the most symbolic aspect of national authority, language is a major site of struggle for majority power and minority resistance. For the purposes of this study, which focuses on the question of Kurdish linguistic rights in Turkey, the sites of struggle for majority power and minority resistance are as follows: the documents o
Abstract in UndeterminedWe analyze empirically export-price strategies across export destinations using detailed firm-product data. Most recent studies using disaggregated data to investigate why firms charge different prices for the same product on different markets focus on the cost component of prices and neglect the markup component. In this paper, we concentrate on the markup component and ex
Construction project life-cycle processes must be managed in a more effective and predictable way to meet project stakeholders’ needs. However, there is increasing concern about whether know-how effectively improves understanding of underlying theories of project management processes for construction organizations and their project managers. Project planning and scheduling are considered as key an
An unbalanced chromosome number (aneuploidy) is present in most malignant tumours and has been attributed to mitotic mis-segregation of chromosomes. However, recent studies have shown a relatively high rate of chromosomal mis-segregation also in non-neoplastic human cells, while the frequency of aneuploid cells remains low throughout life in most normal tissues. This implies that newly formed aneu
This study investigates several commercial selective catalytic reduction (SCR) catalysts (A–E) for application in a high-temperature (approximately 525 °C) and high-concentration (5000 ppm NO) system in combination with CO2 capture. The suggested process for removing high concentrations of NOx seems plausible and autothermal operation is possible for very high NO concentrations. A key property of
Apicidin is a potent histone deacetylase inhibitor (HDACI) that selectively binds to histone deacetylases (HDACs) class I and interferes with the deacetylation process, which results in modification of acetylation level of cellular proteins. The aim of the study was to investigate the potential time and dose dependent cytotoxicity of the test compound, Apicidin, in pancreatic cancer cells Capan-1
The nanowire geometry offers significant advantages for exploiting the potential of III-Sb materials. Strain due to lattice mismatch is efficiently accommodated, and carrier confinement effects can be utilized in tunneling and quantum devices for which the III-Sb materials are of particular interest. It has however proven difficult to grow thin (below a few tens of nanometers), epitaxial III-Sb na
Introduction: This work develops a compartmental model of F-18-choline in order to evaluate its biokinetics and so to describe the temporal variation of the radiopharmaceuticals' uptake in and clearance from organs and tissues. Methods: Ten patients were considered in this study. A commercially available tool for compartmental analysis (SAAM II) was used to model the values of activity concentrati
Using kilometric arrays of air Cherenkov telescopes at short wavelengths, intensity interferometry may increase the spatial resolution achieved in optical astronomy by an order of magnitude, enabling images of rapidly rotating hot stars with structures in their circumstellar disks and winds, or mapping out patterns of nonradial pulsations across stellar surfaces. Intensity interferometry (once pio
Mercury is a hazardous environmental pollutant mobilized from natural sources, and anthropogenically contaminated and disturbed areas. Current methods to assess mobility and environmental impact are mainly based on field measurements, soil monitoring, and kinetic modelling. In order to understand in detail the extent to which different mineral sources can give rise to mercury release it is necessa
An experiment was conducted to follow the fate of the cyanobacterial toxin, nodularin, produced by Nodularia spumigena through ingestion by Mytilus edulis and re-ingestion of faecal material (coprophagy). Mussels were fed with cultures of N. spumigena, and the faeces that were produced were fed to other mussels not previously exposed to N. spumigena. Concentrations of nodularin were measured in th
