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Popular Abstract in Swedish Vävnadskallikrein (VK) är ett äggvitespjälkande protein som dels kan aktivera vävnadsnedbrytande enzymer som kollagenas och gelatinas och dels spjälkar kininogen till kininer (bradykinin och kallidin). Via bindning till speciella kininreceptorer (B2 receptorer) som finns överallt i kroppen, styr kininerna olika processer i de flesta av kroppens organ och vävnader såsom Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. A large release of tissue kallikrein from the pancreatic gland

There is strong evidence for the importance of genetic factors in idiopathic autism. The results from independent twin and family studies suggest that the disorder is caused by the action of several genes, possibly acting epistatically. We have used cDNA microarray technology for the identification of constitutional changes in the gene expression profile associated with idiopathic autism. Samples

We present a new technology for integrating tunnelling devices in three dimensions. These devices are fabricated by the combination of the growth of semiconductor heterostructures with the controlled introduction of metallic elements into an epitaxial layer by an overgrowth technique. First, we use a new type of tunnelling transistor, namely a resonant-tunnelling permeable base transistor. A simpl

Purpose: To describe, by use of a phenomenological approach, how relatively young trans-femoral amputees experienced their amputation and their coping strategies in the acute phase and over time. Method: Eleven trans-femoral amputees, median age 33.5 years, were interviewed. The amputation was caused by tumour, motorcycle accidents or work-related traumas. Amputation was made in median 7.5 years

Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.The present report presents an experimental study of leaching of concrete caused by water percolating through the concrete, or by diffusion from concrete to external water in contact. An apparatus was designed and constructed in which de-ionised water could be forced, by external pressure, through a number of concrete specimens of differing characteristics. It was found that, whereas the initial w

The article describes full-scale backdraft experiments in a shipping container using methane as a fuel. Numerical modelling has followed the experimental setup. The numerical simulations show the initial gravity current, the ignition, the spreading of flame in the enclosure, the external fireball, and the subsequent decay. The Detached Eddy Simulation (DES) approach has been used to model turbulen

A thermostable glycoside hydrolase family-10 xylanase originating from Rhodothermus marinus was cloned and expressed in the methylotrophic yeast Pichia pastoris (SMD1168H). The DNA sequence from Rmxyn10A encoding the xylanase catalytic module was PCR-amplified and cloned in frame with the Saccharomyces cerevisiae alpha-factor secretion signal under the control of the alcohol oxidase (AOX1) promoto

Molecular characteristics were determined for native waxy maize starch and maize starch modified in different way (by mechanical treatment or/and acid hydrolysis). Recrystallisation behaviour was studied. Methods used in this study were MALLS, HPAEC-PAD, NMR, DSC, SEM, light microscopy. Five starch materials were subjected to storage under the same conditions in the presence of water (70 w/w%). Mo

Strong-field phenomena driven by an intense infrared (IR) laser depend on during what part of the field cycle they are initiated. By changing the sub-cycle character of the laser electric field it is possible to control such phenomena. For long pulses, sub-cycle shaping of the field can be done by adding a relatively weak, second harmonic of the driving field to the pulse. Through constructive and

There is a strong need for a productive and innovative infrastructure sector because of its monetary value and importance for the development of a sustainable society. An increased level of industrialization is often proposed as a way to improve efficiency and productivity in construction projects. In prior literature on industrialized construction, there are however neither many studies addressin

The current work of developing a control simulation benchmark goes back to the work carried out within the COST Action 682 (“Integrated Wastewater Management”) and the IAWQ Task Group on Respirometry-Based control of the Activated Sludge Process in the late 90s. The work was continued in COST Action 624 until 2003 (Copp 2002). In 2005, the IWA Task Group on Benchmarking of Control Strategies for W

Wastewater treatment is a worldwide necessity that is even more crucial to countries deprived from abundant fresh water sources or unable to afford advanced and costly processes. With this perspective, this thesis was conducted within an Egyptian-Swedish research collaboration that aimed to develop solar-based (as free renewable energy source available locally) process for hazardous wastewater tre

Hollow structures on the submicrometer scale (urn) are obtained with the assembly of polyelectrolytes according to the layer-by-layer (LbL) technique. Following the LbL procedure, polymers alginate and chitosan were alternatively adsorbed on a vesicular template made of didodecyldimethylammonium bromide (DDAB). Evidence for the removal of the vesicular template entrapped in the alginate/chitosan f

The fight between a human host and a bacterial pathogen is highly complicated; each party tries to outshine the other in the race for survival. In humans, the innate immune system-in particular the complement system-functions as the first line of defence against invading pathogens. During the course of evolution, however, pathogens, in order to survive and perpetuate within a host, developed multi

The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops varies. Mathematical and computational analyses have suggested that loop complexity affects the overall flexibility of the oscillator, including

The diffractive process ep -> eXY, where Y denotes a proton or its low mass excitation with M-Y < 1.6 GeV, is studied with the H1 experiment at HERA. The analysis is restricted to the phase space region of the photon virtuality 3 <= Q(2) <= 1600 GeV2, the square of the fourmomentum transfer at the proton vertex vertical bar t vertical bar < 1.0 GeV2 and the longitudinal momentum fraction of the in

New tools and forms of cooperation at the landscape level are needed in order for forestry and environmental conservation to co-exist in areas with many land owners. Awareness has existed for several years in Sweden that cooperation at the landscape level is essential for protecting areas of high environmental value. This awareness has come to expression in several projects and initiatives. One of