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Background and purpose: During radiotherapy, rectal cancer patients show inter-fractional internal motion that effects the delivered dose distribution. The purpose of this work is to study I) the inter-fractional bladder volume change, II) the effect of bladder volume change on bowel dose distribution, III) the effect of bladder optimization on the relationship between bladder volume and bowel dos

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Hjärtsvikt betecknar ett syndrom som innebär att hjärtat har otillräcklig förmåga att försörja kroppen med blod. Detta kan antingen bero på att hjärtat inte kan fyllas med eller stöta ut tillräckligt med mängd blod. Patienter med hjärtsvikt har i allmänhet hög dödlighet, detta trots att stora framsteg har gjorts avseende behandlingen av hjärtsvikt, speciellt sedan 1980-talet. Femårsöverlevnaden föIntroduction: Despite major advances, the incidence rate and mortality of heart failure (HF) remains high, with a five-year survival of approximately 50%. At the time of inception of this thesis the familial risks of HF, including the aspects of mortality, were largely underdetermined. This thesis is composed of four papers with the main aims as follows:To determine the risk of hospitalization of

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In this concluding chapter, our aim is to outline the state-of-the-art within the deliberated topic in order to identify challenges for future research. Firstly, reminiscent of George Orwell’s aphorism “who controls the past controls the future”, we stress the importance of research into the origins of degraded and restituted towns in order to understand the socio-economic context that has shaped

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Pain, use of painkillers and alcohol are highly prevalent in the general population. Aims of the study were to describe differences in pain, alcohol consumption and use of painkillers among two 60 year old birth cohorts stratified by gender. Participants were recruited from the Skåne centre of The Swedish National study on Aging and Care, a multicentre, prospective, longitudinal study. The sample

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Many problems concerning resource management in modern communication systems can be simplified to queueing models under Markovian assumptions. The computation of the optimal policy is however often hindered by the curse of dimensionality especially for models that support multiple traffic or job classes. The research focus naturally turns to computationally efficient bounds and high performance he

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Popular Abstract in Swedish Denna avhandling föreslår förbättringar av vissa verktyg som svenska myndigheter använder för samhällssäkerhet och krishantering; krishanteringsutvärderingar, krishanteringsövningar samt organisatoriska riskbedömningar. Avhandlingen undersöker även hur visualiseringar av säkerhetskulturdata kan stödja utveckling av säkerhetskultur. Forskningen motiverades av praktiska bThis thesis suggests improvements of selected parts of the Swedish authorities’ toolkits for societal safety and crisis management; crisis response evaluations, crisis management exercises and organizational risk assessments. The thesis also explores how visualizations of safety culture data can be used to support safety culture development. The research was motivated by practical needs and delive

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The aim of the project MASTER (MAnaging Speeds of Traffic on European Roads) was to produce information that can be cited in the preparation of national and EU decisions concerning speed management and speed control equipment standards. For this purpose, the project looked for answers to three key questions: 1)What are acceptable ranges of speeds? 2)What are the key factors influencing drivers’ ch

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Sverige har uppmärksammats internationellt för sin aktiemarknad av bland annat EU-kommissionen. Samtidigt har farhågor lyfts av akademiker där s.k. emissionsarbitrage beskrivs som ”riskfri överavkastning” för professionella aktörer på bekostnad av vanliga sparare. Syftet med uppsatsen är att under-söka samt analysera gällande normer om god sed på aktiemarknaden som finns beträffande riktade nyemisSweden’s stock market has attracted international attention, including from the European Commission, while researchers have at the same time warned that so called issuance arbitrage can give professional investors “risk free excess returns” at the expense of ordinary savers. This thesis examines the norms of good practice that apply to directed new share issues in order to clarify when such issues

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Problem: The relations between first and second tier suppliers within the automotive industry have changed drastically during recent years. Previously involving the supply of simple components, today the relation involves collaborative product development of complex subsystems. The situation is rather new for the actors, hence there are a number of problems that act as restraints for the collabora

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Background Breast cancer is the most frequently diagnosed cancer in women. Survival is generally considered favourable, yet some patients remain at risk of early death. We aimed to assess whether comprehensive whole-genome sequencing (WGS) linked to mortality data could add prognostic value to existing clinical measures and identify patients who might respond to targeted therapeutics. Methods In t

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Background: Heavy-flavor modification in relativistic p(d) + A collisions are sensitive to different kinds of strong-interaction physics ranging from modifications of the nuclear wave function to initial- and final-state energy loss. Modifications to single heavy-flavor particles and their decay leptons at midrapidity and forward rapidity are well established at the Relativistic Heavy Ion Collider

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The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei

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Popular AbstractDen nya världsordningen som Castells kallar för nätverksamhälle skapar en konflikt mellan globalisering och identitet. I detta avseende blir frågan om identitet och etniska gränser, i Barths mening, ett centralt tema för att förstå samhällsförändringar. Globaliseringsprocessen håller på att skapa en försvagning av det civila samhället och med detta försvagas också förhållandena melThe new world order, that Castells denominates network society, generates a conflict between the globalisation and identity. In this sense the questions of identity and ethnic boundaries,in Barth’s meaning, emerge as a central subject to understanding societal changes. Globalisation is causing a weakening of the civil society, the relationship between the nation state and the people is also debili

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Popular Abstract in Swedish Avhandlingen behandlar en hinduisk, framför allt sydindisk form av divination vid namn nadi-läsning, uppbyggd efter astrologiskt mönster men med vissa utmärkande särdrag, framför allt uppläsandet av föregivet färdigskrivna texter, tillskrivna gudomliga eller övermänskliga författare, i vilka klientens levnadsöde skall ha nedtecknats långt före dennes födelse. EftLike all divination, Hindu astrology (jyotisa) is concerned with central religious issues such as man’s relation to the world, moral responsibility, and the revelation of a coherent divine order underlying human experience. Comprising a descriptive as well as a prescriptive aspect, jyotisa allows for both prediction and the exercise of free will. This double nature enables a seamless

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This second digital edition includes my research from 2013 until November 2015. There are many important changes from de first version. This version introduces the Technocratic Mode of Production based on the exploitation of the consumers. It includes a complete description of the cyborg society as it is today, the new castes that constitute it and the economic acts that regulate the new Mode of P

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The aim of this work is to study present Rwandan social identities. The aim is made operational by posing the question; how are group identities produced and reproduced in Rwanda? In order to answer this the study uses the bourdieuesian notion of habitus, incorporated products of history that are active principles for unification of practices and representations, as the analytical concept of socia

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Den 17 november 2021 röstade Sveriges riksdag igenom regeringens förslag om en ny lag som innebär slopandet av straffrabatt för unga myndiga lagöverträdare vid allvarlig brottslighet. Vidare innebär förslaget att samma straff ska kunna utdömas till 18–20 åringar som till andra myndiga lagöverträdare, däribland fängelse på livstid. Unga myndiga har särbehandlats i svensk rätt i närmare 60 år, men uOn November 17, 2021, the Swedish Riksdag voted in favor of the governments’ proposal for a new law that abolishes the penalty rebate for young adult offenders who committed serious crimes. Furthermore, the law entails that the same punishment can be sentenced to 18–20 years as to other adult offenders, including life imprisonment. Young adult offenders have been treated differently than other adu