Filtyp
BACKGROUND: The isolation of cell-free DNA (cfDNA) from the bloodstream can be used to detect and analyze somatic alterations in circulating tumor DNA (ctDNA), and multiple cfDNA-targeted sequencing panels are now commercially available for Food and Drug Administration (FDA)-approved biomarker indications to guide treatment. More recently, cfDNA fragmentation patterns have emerged as a tool to inf
Pheochromocytoma and paraganglioma (PPGL) are rare tumours and at least 30% are part of hereditary syndromes. Approximately 20% of hereditary PPGL are caused by pathogenic germ line variants in genes of the succinate dehydrogenase complex (SDHx), TMEM127 or MAX. Herein we present guidelines regarding genetic testing of family members and their surveillance based on a thorough literature review. Al
BACKGROUND: The risk of venous thromboembolism is high after total hip arthroplasty and could persist after hospital discharge. Our aim was to compare the use of rivaroxaban for extended thromboprophylaxis with short-term thromboprophylaxis with enoxaparin.METHODS: 2509 patients scheduled to undergo elective total hip arthroplasty were randomly assigned, stratified according to centre, with a comp
Accessing embedded test and monitoring circuitry (the so-called embedded instruments) in in-field products can reduce maintenance and diagnostics costs. Performing such access can be facilitated when done over an internal system bus, due to that it might be faster and less cumbersome to reach a system processor (on an in-field product) over a network interface, compared with the effort and speed o
Aims: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive condition caused by deposition of transthyretin amyloid fibrils in the heart and is associated with poor quality of life and a shortened lifespan. This study aimed to describe the prevalence, clinical characteristics, and mortality of patients with ATTR-CM, using multiple national health registers in Denmark, Finland, Norway, an
Background: The protein C anticoagulant system plays a key role in maintaining the hemostatic balance. Although several studies have identified thrombomodulin gene (THBD) variants among venous thromboembolism (VTE) patients, the role of THBD in relation to VTE in humans remains to be clarified. Objectives: This study aimed to determine the thrombotic risk of rare and common THBD variants in a larg
Abstract This thesis addresses the effects of parking accessibility on work commuting and the potential to use parking policies as a tool to support mobility management and enhance sustainable commuting in Lund. The structure rests on two folds: first, it provides a theoretical background on different parking policies and factors influencing work commuting; second, it provides an analysis of Lund
Sedan hösten 2006 har lagstiftningsprocessen fått ett nytt inslag. Ett oreglerat och nästan okänt inslag, men ack så viktigt. När de fyra borgerliga partierna under åren 2004-2006 förberedde ett eventuellt regeringsskifte efter valet 2006 så var den s.k. Äntringsstyrkans arbete mycket viktigt. Ett av deras viktigaste förslag var att en mekanism för all samordning mellan de fyra partierna skulle inSince fall 2006, the legislative process has a new element. An unregulated and almost unknown element, however very important. When the four center right wing parties during the years 2004-2006 were preparing a possible change of government after the 2006 election, the work of the so-called “Äntringsstyrkan” was very important. One of their main proposals was that a mechanism for all coordination
Det kan sägas att extraordinära rättsmedel och dess resningsregler i dagens rättegångsbalk 58 kap. härstammar från konungens förmånsrätt att bryta domar under 1100-talets högmedeltid. Begreppet rättskraft och behovet av att angripa lagakraftvunna domar slog inte igenom förrän i slutet av 1600-talet. Dåvarande regler tillämpades formellt inte vid brottmål, men kom ändå att i praktiken att göra det.One can say that the extraordinary remedies and their rules regarding the relief for a substantive defect in today’s Code of Civil Procedure (Section 58) originate in the king’s preferential right to annulate court decisions during the late middle ages in the 1100s. The concept of legal force and the need to impugn court decisions that have taken legal effect was not noticed before the end of the
Cirrus clouds are high-level ice clouds covering ≈ 30% of Earth’s surface. The cirrus clouds ice crystals can be formed by heterogeneous or homogeneous nucleation, where temperatures for heterogeneous nucleation was set to -38 - -30 °C and for homogeneous nucleation below -42 °C. The study will focus on microphysical properties of cirrus clouds in the tropics, 0-30°, and the mid-latitudes, 30-60°,
The following is a fire-safety-risk-assessment with the purpose of evaluating the safety of the shopping center Punkt in Västerås, Sweden. The risk assessment is an assignment in the course Brandteknisk Riskvärdering given at Lunds Tekniska Högskola, Lunds University, Sweden. Punkt is a shopping center on floor 3 and 3.5 of a 9-story building. The assessment will focus on the possibility of safely
Denna studie syftar till att undersöka hur cancelleringsprocesser ser ut i samband med skandaler för influencers och hur de utvecklas under tidens gång. Detta görs i form av en fallstudie, närmre specifikt skandalfallet med Margaux Dietz som inträffade år 2022. För att kunna dra vetenskapliga slutsatser baserat på empiri som följer narrativet, tar rapporten fäste i två teoretiska utgångspunkter -
Binära föreningar beståendes av sällsynta jordartsmetallerna och rutenium uppvisar intressanta egenskaper såsom superledande förmåga och intressanta magnetiska egenskaper. För att förstå varför vissa föreningar uppvisar sådana egenskaper är det essentiellt att studera föreningarnas kristallstruktur. I denna rapport undersöks föreningar, i 35-38 at. % Ru regionen, beståendes av praseodym, neodymiumBinary alloys comprising of the rare earth metals along with ruthenium, RE-Ru, have been noted to display superconductivity at low temperatures. Furthermore the alloys display interesting magnetic properties such as anomalies in magnetization measurements below the magnetic ordering temperature. In order to understand how some compounds obtain these intrinsic properties it is vital to investigate
With this thesis we want to prove that by using a single formula for picking stocks, Joel Greenblatt’s ‘’Magic Formula’’, it is possible to achieve returns higher than those achieved by a related index. To prove this, we will construct a portfolio, according to “The Magic Formula”, and backtest the portfolio in the Swedish stock market. The test period will be March 1999 to January 2010 and we wil
Image classification systems have been widely applied in smartphones, industrial inspection, and automated devices. However, in real-world scenarios, existing classifiers often produce inconsistent or incorrect predictions due to factors such as image degradation, inter-class similarity, and model instability, thereby reducing the overall performance of the system. To address these issues and enha
