Filtyp
β-Amyloid peptide accumulation plays a central role in the pathogenesis of Alzheimer's disease. Aberrant β-amyloid buildup in the brain has been shown to be present both in the extracellular space and within neurons. Synapses are important targets of β-amyloid, and alterations in synapses better correlate with cognitive impairment than amyloid plaques or neurofibrillary tangles. The link between β
Diffuse large B-cell lymphoma (DLBCL), the most common type of non-Hodgkin’s lymphoma (NHL) in adults, accounts for approximately 30-40% of newly diagnosed lymphomas worldwide. Environmental factors, such as viruses and bacteria, may contribute to cancer development through chronic inflammation and the integration of oncogenes, and have previously been indicated in cervical cancer, hepatocellular
Efficient CAD tools are desired to reduce the increasing design efforts when algorithms implemented on ASICs are getting more complicated. For microprogrammed accelerator design, a control unit synthesizer is of great importance since the manual design of a controller for a complicated task requires substantial effort. While a hardware specific implementation results in higher performance or lower
Examensarbetets titel: Kun(d)skapsintensivt arbete - Ledarskap och motivation i en kundnära kunskapsintensiv organisation Seminariedatum: 15 januari 2026 Kurs: FEKH49 - Examensarbete i organisation på kandidatnivå, 15 högskolepoäng Författare: Filippa Kapoor Åberg och Sakarias Moberg Handledare: Stefan Sveningsson Fem nyckelord: Kunskapsintensiv verksamhet, kundstyrning, ledarskap, motivation, psyTitle: Knowledge(client) intensive work - Leadership and Motivation in a client-centered knowledge-intensive firm Seminar Date: 15th January 2026 Course: FEKH49 - Bachelor’s degree thesis in Management and Organization, 15 credits. Authors: Filippa Kapoor Åberg and Sakarias Moberg Supervisor: Stefan Sveningsson Five Keywords: Knowledge-intensive firms, Client control, leadership, motivation, psych
Globalization pressures have today inflicted significant changes in the way industrial enterprises are organized and how products are developed, manufactured and brought to market. A common denominator in many of these enterprises is the utilization of an organizational structure based on networks composed of divisions and supplier companies dispersed all over the world. ln these global enterprise
OBJECTIVE: To describe the distribution of HIV-1 variants in population-based national surveys conducted in sub-Saharan African countries between 2015 and 2022.DESIGN: Multicountry analysis.METHODS: Sixteen population-based national surveys, conducted between 2015 and 2022, were analyzed. Survey participants were eligible if HIV genotyping was successful. In most countries, people with HIV (PWH) w
Background Approximately one-third-of patients with transient new-onset atrial fibrillation (AF) during hospitalization for noncardiac surgery or medical illness will have recurrent AF within 1 year when assessed using two 14-day ECG monitors. The proportion of patients that would be diagnosed with recurrent AF with less monitoring is unknown. Methods We used data from a prospective cohort of part
Diffuse nitrate pollution remains a persistent threat to drinking-water resources, yet current predictive frameworks rarely capture how the spatial composition (land-cover fractions) and configuration (landscape fragmentation) of land systems jointly modulate leaching. This study presents a novel multiscale framework integrating hydro-climatic, soil and anthropogenic predictors with land-cover fra
Background: Patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HCT) often face complex and evolving needs throughout recovery. Person-centred nursing (PCN) is essential in this context yet remains underexplored in specialised care settings. In Sweden, the Assessment of Rehabilitation Needs Checklist (ARNC) is commonly used in cancer care, but its role in supporting perso
Background: Current guidelines for the treatment of severe TBI recommend maintaining a cerebral perfusion pressure (CPP) at 60–70 mmHg. In our institution, as well as others, an alternative algorithm—originally named the Lund concept—has been used. This treatment algorithm employs metoprolol and clonidine to limit CPP, accepting levels below 60 mmHg, with the aim of reducing cerebral edema. Previo
Vegetable by-products, produced in large quantities worldwide, contain significant amounts of bioactive compounds and fiber, which have been shown to offer health benefits, such as regulating blood lipid levels. Dyslipidemia, a primary target in the clinical metabolic control of susceptible populations, is strongly influenced by diet. Hence, this systematic review aims to present the main findings
BACKGROUND: Growing concerns over the environmental and human health impacts of conventional insecticides have intensified interest in botanical alternatives, including essential oils. However, their compositional complexity poses challenges for quality control and consistent efficacy. This study evaluated and compared the predictability of nonparametric and parametric models for predicting the mi
Previously we identified Mt4, a phosphate starvation inducible cDNA from Medicago truncatula which is down-regulated in roots in response to phosphate fertilization as well as colonization by arbuscular mycorrhizal (AM) fungi. Here we present further studies of Mt4. Expression was highly sensitive to exogenous applications of phosphate fertilizer; transcripts were abundant in roots fertilized with
The connection between neuroscience, popular media and lay perceptions of the brain involves the framing of complex scientific processes and results through familiar cultural narratives and metaphors. Such narratives are often built on the premise that neuroscience, with the help of powerful new technologies, will finally solve the mysteries of brain and mind, consciousness and morality. At the sa
Reactive oxygen species (ROS) are important contributors to the secondary injury cascade following traumatic brain injury (TBI), and ROS inhibition has consistently been shown to be neuroprotective following experimental TBI. NXY-059, a nitrone free radical trapping compound, has been shown to be neuroprotective in models of ischemic stroke but has not been evaluated in experimental TBI. In the pr
The main objective was to estimate the frequency of early vascular aging (EVA) in a sample of subjects from Latin America, with emphasis in young adults. We included 1416 subjects from 12 countries in Latin America who provided information about lifestyle, cardiovascular risk factors (CVRF), and anthropometrics. We measured pulse wave velocity (PWV) as a marker of arterial stiffness, and blood pre
The paper proposes a new multiple window method for estimating a peaked spectrum. The multiple windows are adapted to the signal, giving a less biased estimate for estimation of peaks than does the Thomson multiple window method. Still the result from estimation of a flat spectrum shows comparable results in variance reduction. The method is based on solution of an eigenvalue problem where the eig
Background: Heparin-binding protein (HBP) is a neutrophil-derived protein advocated as a biomarker in sepsis. We evaluated plasma HBP as a predictor of post-injury sepsis in trauma patients. Methods: Ninety-seven trauma patients were studied during the first week of intensive care. Injury-related data were collected and clinical parameters registered daily. Plasma HBP was sampled on day 1, 3 and 5
Introduction: Roux-en-Y gastric bypass (RYGB) causes more rapid and enhanced absorption of alcohol. RYGB patients have also been reported to use more inpatient care for alcohol-related disease than do patients after other bariatric procedures. The present study was designed to evaluate alcohol consumption level before and after gastric bypass using a sensitive and specific alcohol biomarker. Mater
Aims: Ankle–brachial index (ABI) is the most commonly used test when diagnosing peripheral vascular disease and is considered a marker for cardiovascular risk. Transcutaneous oxygen pressure (TcPO2), a test associated with microvascular function, has in several studies shown better correlation with diabetic foot ulcer (DFU) healing. Whether a low TcPO2 could be a marker for mortality in the high-r
