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Popular Abstract in Swedish SVENSK SAMMANFATTNING Den kliniska effekten av läkemedel som administreras till näsa eller lunga beror på läkemedlets egenskaper och på dess lokala deposition. Depositionsstudier är därför värdefulla för att kunna karakterisera olika beredningar. Depositionen påverkas av partiklarnas storlek och hastighet, genom att stora partiklar med hög hastighet ger upphov till en hThe local deposition, pharmacokinetics, and systemic activity of inhaled and intranasal glucocorticosteroids in different formulations and devices(ICSs) has been investigated. After nasal administration of the ICS budesonide (Bud), the systemic availability (F) was found to be significantly higher from an aqueous pump spray and from the powder inhaler Turbuhaler, than from a pressurized metered do

Critical systems must comply with safety standards in many application domains. This involves gathering safety evidence in the form of artefacts such as safety analyses, system specifications, and testing results. These artefacts can evolve during a system’s lifecycle, and impact analysis might be necessary to guarantee that system safety and compliance are not jeopardised. Although extensive rese

Abstract in UndeterminedThe medical technology (medtech) industry in Sweden is situated withina complex innovation ecosystem, in which various stakeholders from the public,private and academic sectors need to collaborate to meet demands on effective andeffi cient healthcare. Demographics are changing and those in need of healthcare arenot only larger in numbers than ever but they are also more kno

Popular Abstract in Swedish Från mitten av 1970-talet utvecklades i Sverige en ny form av behandling för missbrukare av narkotika och alkohol: Miljöterapi med psykoterapi. Miljöterapin innebar en längre tids drogfri vistelse på behandlingshem där ett konstruktivt, bejakande och människovärdigt klimat avsågs vara behandlande dygnet runt. Psykoterapin var i regel schemalagd transaktionsanalytisk (TAThis monograph studies the outcomes of transactional analysis (TA) psychotherapy with addicts of heavy drugs in long time residential treatment (one year or more) at Swedish therapeutic communities (TCs) during the 1990s. Two sets of data were obtained: The primary material concerned results of approximately one year of TA-therapy; the secondary specific TA-therapy results versus total mileau ther

Popular Abstract in Swedish Denna avhandling baserar sig på de erfarenheter av Internet som ett antal människor med betydande kroppsliga funktionsnedsättningar gjort. Personerna i studierna är erfarna och duktiga dator- och Internetanvändare och har få eller inga funktionshinder i dator och online världen, men däremot stora funktionshinder i den fysiska världen. Deras functioning, förmåga attThis thesis is based on the Internet experiences of people with significant mobility/physical impairments who are proficient and experienced computer users in their computer world but have limitations in mobility that severely restrict their functioning in the physical world. The Internet functioning of this group is analysed by means of the factors attitude, control and enabling, with the m

The effect of process stream recirculation on ethanol production from steam- pretreated softwood based on simultaneous saccharification and fermentation (SSF) was investigated for two process configurations. In the first configuration, a part of the stillage stream after distillation was recycled and, in the second configuration, the liquid after SSF was recycled. The aim was to minimize the energ

Purpose. To describe, by use of a phenomenological approach, how transfemoral amputees experience their first meeting and subsequent interaction with hospital staff in the acute phase, in the long term and suggestions for future care-giving. Method. Eleven transfemoral amputees, median age 33.5 years, were interviewed. The amputations, performed in median 7.5 years before the interview, were cause

Tendon injuries can occur in athletes and workers whose tasks involve repetitive, high-force hand activities, but the early pathophysiologic processes of tendinopathy are not well known. The purpose of this animal study was to evaluate the effects of cyclical tendon loading on the densities of cells producing growth factors such as vascular endothelial growth factor (VEGF), its receptor, vascular

In order for an agent to achieve its objectives, make sound decisions, communicate and collaborate with others effectively it must have high quality representations. Representations can encapsulate objects, situations, experiences, decisions and behavior just to name a few. Our interest is in designing high quality representations, therefore it makes sense to ask of any representation; what does i

Manual cartographic generalization is a simultaneous process. However, most automatic approaches so far have been sequential; generalization operators are applied one at a time in a certain order. This has been the case both for model generalization (generalization of the conceptual model) and graphic generalization. Our research seeks to demonstrate that the graphic part of cartographic generaliz

Two different mathematical methods of implementing a detailed kinetic soot model have been employed in this work. The theoretical description of the soot modeling employed in this work is divided into three parts. Initially a detailed kinetic soot model is described from a chemistry and physics perspective. The soot model is then elaborated into mathematical form, starting with the formulation of

The task aims to investigate if it is possible to produce two portion packages with the same technical equipment and cycle time as for the 1000 ml Carton Bottle package. The assigner is MSc Pär Andersson at Tetra Pak. The work followed Ulrich and Eppingers “front-end process” and started with an interpretation of the client needs translated to target specifications. Several package concepts were d

International law related to patents, on the one side, and human rights, on the other, both constitute interesting areas of law on their own. From time-to time the two distinct fields of international law intertwine. A tragic but highly relevant example is the ongoing HIV/AIDS epidemic. The core of law-related considerations of the HIV/AIDS epidemic consists of specific parts of the two fields, na

This dissertation offers a unique examination of Muslim masculinities and marginalized sexualities in Lebanon, and is a contribution to the growing body of gay and lesbian studies with a focus on Muslims living in The Middle East. It contributes to the theoretical and methodological development of Islamic studies by introducing and using a queer approach to study marginalized sexualities in relati

Hybridization can drive the convergence of territorial and sexual signals. However, non-genetic processes such as competition, environment matching, or cultural transmission, also generate this pattern. We investigated the effect of hybridization on song convergence between two interspecifically territorial warblers in a moving hybrid zone. We confirmed song convergence in each species. Using an A

Low-dimensional, many-body systems are often characterized by ultraslow dynamics. We study a labelled particle in a generic system of identical particles with hard-core interactions in a strongly disordered environment. The disorder is manifested through intermittent motion with scale-free sticking times at the single particle level. While for a non-interacting particle we find anomalous diffusion

Patents on traditional knowledge and the issue of biopiracy has been a debated issue since the Uruguay Round in the early 1990s. In order to handle this problem, the United Nations established the Convention on Biological Diversity and a subsidiary working group on Access and Benefit Sharing. This is supposed to help traditional knowledge holders claim their rights to benefit sharing when commerci

The scientific consensus on climate change is clear, but the social consensus in the United States has yet to concur. Mainstream explanations for the failure of the American public to engage the climate change problem often refer to an information deficit or lacking political will, but have not proven sufficient in accounting for such behavior. A deeper look reveals that the problem lies at the so

Previous studies has concentrated around the area of children living with parents who has a alcohol problem, hence less research has focused on the children when they have become adults and moved away from home. I contacted a Danish organization, named Tuba, which provides free therapy to people, in the ages from 14 to 35, where one or both parents have an alcohol problem. In collaboration with Tu