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Microsoft Word - Cell therapy 2019_MPreport_GPV.docx Cell therapy 1. Short description of the platform The translational Cell Therapy platform was established to facilitate the gap between pre-clinical development and clinical trials. The transition from basic research to a clinically applicable therapy is a complex process that requires expertise from experimental and clinical researchers and als

https://www.multipark.lu.se/sites/multipark.lu.se/files/cell_therapy_report_2019_.pdf - 2026-07-06

A recently developed vertical borehole ground heat exchanger model that accounts for transit time effects and time-varying short-circuiting heat transfer has been validated against two multi-flow-rate thermal response tests (MFR-TRT). The MFR-TRT, when performed with a wide range of flow rates, results in significant changes in the borehole thermal resistance, the borehole internal thermal resista

The osmotic pressure of polyelectrolyte solutions as a function of concentration has been calculated by Monte Carlo simulations of a spherical cell model and by molecular dynamics simulations with periodic boundary conditions. The results for the coarse-grained polyelectrolyte model are in good agreement with experimental results for sodium polyacrylate and the cell model is validated by the bulk

The current study presents methods to predict the governing crack initiation site and fatigue crack initiation life of components with surface roughness. The surface topography is measured with white light interferometry and explicitly accounted for in detailed finite element models. The micro-notch stress fields are used in multiaxial and uniaxial crack initiation criteria where the relative stre

Dextrose syrups are produced from starch by liquefaction combined with saccharification. In the conventional production process, rotary vacuum filters (RVFs) with a diatomaceous earth (kieselguhr) coating as filter aid are often used for removal of the so-called mud phase after the liquefaction and saccharification step. This mud phase consists of insoluble impurities and suspended solids such as

It is important to minimize transmission heat transfer losses through the building envelope when designing and building energy efficient buildings in heating dominated climates. In such a climate, a large part of the space heating demand is caused by transmission heat transfer losses through the building envelope. Calculations of these losses must be carried out in a correct way to ensure a proper

From 1979 through 1991, 19 infants with absent pulmonary valve syndrome and airway obstruction were seen for surgical treatment. All patients underwent extensive pulmonary artery aneurysmorrhaphy using cardiopulmonary bypass. Fourteen patients had simultaneous transatrial ventricular septal defect (VSD) closure, infundibular resection, and placement of a short transannular patch; 2 had transventri

A semi-empirical power law-based theory has been developed to model the crystallization kinetics in precipitating systems for CO2 capture. A more reliable activity-based theory and simplified concentration-based crystallization kinetics have also been derived for a gas-liquid-solid system in which CO2 evolution might be unavoidable during the experiments performed to determine crystallization kine

Background: In an intensive care unit (ICU), privacy and proximity are reported to be important needs of dying patients and their family members. It is assumed that good communication between the ICU team and families about end‐of‐life decisions improves the possibilities of meeting families’ needs, thus guaranteeing a dignified and peaceful death in accordance with end‐of‐life care guidelines. Th

BACKGROUND: Glutamic acid decarboxylase-65 (GAD65), the enzyme that catalyzes the formation of gamma-aminobutyric acid (GABA), is the major autoantigen in both type 1 (insulin-dependent) diabetes and stiff-man syndrome (SMS). The observation that GAD65 autoantibodies may be present for years before the clinical onset of diabetes raises the question of when GAD65 is available to initiate an immune

The long-term psychological effects resulting from carrier testing and prenatal diagnosis (PD) of haemophilia were evaluated by comparing mental symptomatology scores (Symptom Check List, SCL-90) for 50 carriers of haemophilia who had undergone PD about five years earlier, 55 carriers who had not undergone PD and 262 control women who were not carriers. All of the women had children. Carrier testi

A new health surveillance protocol for work-related upper-extremity musculoskeletal disorders has been validated by comparing the results with a reference protocol. The studied protocol, Health Surveillance in Adverse Ergonomics Conditions (HECO), is a new version of the reference protocol modified for application in the Occupational Health Service (OHS). The HECO protocol contains both a screenin

The influence of cross-flow velocity and transmembrane pressure on the optimal back-shock frequency and normalized net flux during back-shocking has been studied using a semi-analytical mathematical model. The model uses the flux as a function of time without back-shocking together with knowledge of the streamlines and pathlines during the back-shock cycle to predict the optimal normalized net flu

It is well known that Max-Weight type scheduling algorithms are throughput optimal since they achieve the maximum throughput while maintaining the network stability. However, the majority of existing works employing Max-Weight algorithm require the complete channel state information (CSI) at the scheduler without taking into account the associated overhead. In this work, we design a Scheduling and

Objective: Apart from improved health outcomes, treatment convenience per se may have a value to individuals. This is sometimes referred to as process utility and can be estimated in terms of willingness-to-pay (WTP) or quality-adjusted life-years (QALYs). Previous research has produced multiple studies on QALY gains and WTP estimates of insulin-related attributes. There are, however, significant

The aim of this article is to analyze reported changes in outdoor mobility, increased/unchanged/decreased, for a sample of older people (>62 years) in two regions in Sweden, who have transitioned from a two-person to a single-person household during the two years since the study was conducted. The target group (N=162) consists of all people who had transitioned to a single-person household in a ra

The German Federal State of Saxony aims to increase forest cover, supported by the implementation of afforestation programs. To analyze consequences of an increase in forest cover, this study investigates possible trade-offs between carbon storage and plant biodiversity caused by afforestation. Six afforestation scenarios with total forest cover ranging from 27.7% to 46% were generated in the Muld

The study makes an inventory of learning opportunities young people were offered in connection with CEI 2016, one of the annual international conferences organized by the NGO named Caretakers of the Environment International (CEI), which year 2016 took place in Aalborg in Denmark. The learning opportunities offered by this transnational learning community are discussed in relation to some essenti

A basic theoretical model that describes the effects of flow in and out of the imaging plane in nuclear magnetic resonance (NMR) images, obtained with the standard pulse sequences single spin echo, multiple spin echo, and inversion recovery, is presented. Theoretically calculated signal values are compared with experimental results obtained from single-slice images of a flow phantom for variable f