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Background/introductionFlecainide is a commonly used efficient antiarrhythmic drug against atrial fibrillation (AF). P-wave indices reflect the atrial substrate and can predict incident AF, but their role as predictors of treatment outcomes for flecainide-treated AF patients are unknown.PurposeTo assess if P-wave indices can predict efficacy outcomes in long-term flecainide treated AF patients.Met
This chapter discusses creative agency in performing arts. It departs from three theatre productions all produced in different contexts. When exploring new formats with artists from many different art fields, the question of creative agency becomes pivotal: artistic dilemmas can’t be solved by any one artist alone-joint efforts are needed to find solutions on how to blend different modes of repres
Many forensic psychiatric inpatients have difficulties regulating aggressive behavior. Evidence of effective aggression treatments is limited. We designed and investigated the effectiveness of a transdiagnostic application of a virtual reality aggression prevention training (VRAPT). In this randomized controlled trial at four Dutch forensic psychiatric centers, 128 inpatients with aggressive behav
The molecular self-diffusion coefficients were accessed, for the first time, in solutions of microcrystalline cellulose, dissolved in 30 wt% and 55 wt% aqueous tetrabutylammonium hydroxide, TBAH (aq), and in mixtures of 40 wt% TBAH (aq) with an organic co-solvent, dimethylsulfoxide (DMSO), through pulsed field gradient stimulated echo NMR measurements. A two-state model was applied to estimate α (
BACKGROUND: Ketamine has considerable therapeutic potential in alleviating major depressive disorder and chronic suicidality. However, the clinical diagnosis of neuropsychiatric disorders requires more robust diagnostic criteria. Electroencephalography (EEG) has shown promise in classifying depressive and suicidal patients from healthy individuals. The present study aimed to identify changes in th
Australia is already experiencing climate change losses and damages. Australian governments and other institutional actors acknowledge vulnerability, yet they centre building resilience to climate change. Resilience is frequently used as a synonym for vulnerability reduction, but important ideological differences exist. Indeed, scholars have suggested that resilience, as a politico-ideological too
Core–shell structural ZnSeTe/ZnSe/ZnS quantum dots (QDs) have attracted great attention for advanced illumination and displays because of their environmentally friendly composition, but still suffering from poor photoluminescence (PL) and electroluminescence (EL) performance due to severe non-radiative charge recombination. Herein, a stepwise injection shell growth process to manipulate the monome
This study examines the integration of climate change and biodiversity into business strategies and governance structures of listed firms on the Swedish stock exchange NasdaqOMX Large Cap. The results show clear disparities in the level of integration and the factors driving the integration process. All, but a few small firms, have integrated climate change into business strategies, and are ahead This study examines the integration of climate change and biodiversity into business strategies and governance structures of listed firms on the Swedish stock exchange NasdaqOMX Large Cap. The results show clear disparities in the level of integration and the factors driving the integration process. All, but a few small firms, have integrated climate change into business strategies, and are ahead
Study region: In the Yangtze River basin of China. Study focus: We applied a recently popular deep learning (DL) algorithm, Transformer (TSF), and two commonly used DL methods, Long-Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU), to evaluate the performance of TSF in predicting runoff in the Yangtze River basin. We also add the main structure of TSF, Self-Attention (SA), to the LSTM and G
Exclusive production of dielectron pairs, γγ → e + e −, is studied using Lint = 1.72 nb−1 of data from ultraperipheral collisions of lead nuclei at sNN = 5.02 TeV recorded by the ATLAS detector at the LHC. The process of interest proceeds via photon–photon interactions in the strong electromagnetic fields of relativistic lead nuclei. Dielectron production is measured in the fiducial region defined
Background: In Sweden, vaccine uptake is exceptionally high due to an efficient child immunization program. More than 97% of Swedish children were vaccinated at child health care centers (CHCs) according to the schedule at 2 years of age in 2021. From the age of 6 years, vaccinations are given within the school health care. Maintaining high vaccination coverage over time is one of the central moti
The concept of importance of criteria is used as a central element in several decision making contexts, specifically in value aggregation, e.g. as an input to decision support tools. For example, in the analytic hierarchy process (AHP) decision makers are asked to estimate how much more important one criterion is than another. However, it is not clear how people understand aggregation models based
Popular Abstract in Swedish Denna avhandling behandlar modellsystem för farmaka som har DNA och RNA som mål i cellen. Framförallt behandlar den hur strukturen hos DNA och RNA påverkas av inbindning av olika substanser, samt hur fort denna inbindning sker. Tre olika typer av farmaka behandlas: 1. Platinaföreningar som länge använts som cytostatika, 2. RNA interferens som främst har utvecklats undDrugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. Structural changes were determined by use of chemical probing and circular dichroism (CD),
Electric Hybrid Vehicles, EHV, are under development to provide lower fuel consumption levels and minimize the environmental pollution compared to pure Internal Combustion Engine, ICE, driven vehicles. The EHV is more complex and thus carry many more extra parts than the pure ICE based vehicle. Competing against the pure ICE vehicle in the sense of nonexpensive mass production is hard. This thesis
The extent of behavioral recovery following neural transplantation in part depends on the amount of surviving graft tissue. The main objective of this thesis was to study parameters affecting the survival of embryonic striatal and mesencephalic neurons in experimental models of Huntington's and Parkinson's disease. Firstly, we studied the survival and maturation of embryonic striatal neurons that
Three patients, men aged 47 and 30 and a woman aged 48 years, presented with appendicitis-like symptoms, progressive abdominal distension, and an ovarian pelvic mass, respectively. All three were diagnosed with pseudomyxoma peritonei. Treatment consisted of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC). After a mean follow-up of 64 months (range: 19-89) after
Background and objective: The most common way of closing the cystic duct in laparoscopic cholecystectomy is by using metal clips (>80%). Nevertheless, bile leakage occurs in 0.4%–2.0% of cases, and thus causes significant morbidity. However, the optimal number of clips needed to avoid bile leakage has not been determined. The primary aim of this study was to evaluate bile leakage and post-procedur
The International Water Association (IWA) Benchmark Simulation Models (BSM1 and BSM2) have been successfully used in both industry and academia to test and verify control strategies in wastewater treatment plants (WWTPs). In this study, a new (plant- wide) benchmark simulation model, the BSM2-LT, is developed to evaluate monitoring algorithms. This platform provides opportunities to generate vario
