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Objective To compare PET imaging of tau pathology with CSF measurements (total tau [t-tau] and phosphorylated tau [p-tau]) in terms of diagnostic performance for Alzheimer disease (AD). Methods We compared t-tau and p-tau and 18 F-AV-1451 in 30 controls, 14 patients with prodromal AD, and 39 patients with Alzheimer dementia, recruited from the Swedish BioFINDER study. All patients with AD (prodrom
The lack of any effective therapy along with the aging world population anticipates a growth of the worldwide incidence of Alzheimer's disease (AD) to more than 100 million cases by 2050. Accumulation of extracellular amyloid-β (Aβ) plaques, intracellular tangles in the brain, and formation of reactive oxygen species (ROS) are the major hallmarks of the disease. In the amyloidogenic process, a β-s
Macromolecular crowding in biological media is an essential factor for cellular function. The interplay of intermolecular interactions at multiple time and length scales governs a fine-tuned system of reaction and transport processes, including particularly protein diffusion as a limiting or driving factor. Using quasielastic neutron backscattering, we probe the protein self-diffusion in crowded a
Growing GaAs nanowires with well-defined crystal structures is a challenging task, but may be required for the fabrication of future devices. In terms of crystal phase selection, the connection between theory and experiment is limited, leaving experimentalists with a trial and error approach to achieve the desired crystal structures. In this work, we present a modeling approach designed to provide
Characteristics of the built environment, including access to unhealthy food outlets, are hypothesized to contribute to type 2 diabetes mellitus (T2D). Swedish nationwide registry data on 4,718,583 adults aged 35-80 years living in 9,353 neighborhoods, each with at least 1 food outlet, were geocoded and linked to commercial registers (e.g., restaurants and grocery stores). Multilevel logistic regr
An experimental test system including the oil circulation system and the gas circuit system has been designed and built to explore the effects of the lubricating oil flow rate on the performance of a single-screw compressor, used in a portable natural gas liquefaction process. Outlet pressure, outlet volumetric flow rate, volumetric efficiency, and specific power rate are the parameters for evalua
This thesis investigates the role of interior design elements, especially artwork, in way-searchers’ wayfinding and orientation in hospital environments. The thesis considers the way-searcher’s background and the impact of cultural belonging, occupation, memories, aesthetic preferences, and language, and the influence that such factors might have on the perception of the hospital environment and i
The objective of this paper is to present the main results of an engineering-research project dealing with model-based evaluation of waste streams treatment from a biotech company. This has been extensively done in domestic treatment systems, but is equally important, and with different challenges in industrial wastewater treatment. A new s
Context. The second release of Gaia data (Gaia DR2) contains the astrometric parameters for more than half a million quasars. This set defines a kinematically non-rotating reference frame in the optical domain. A subset of these quasars have accurate VLBI positions that allow the axes of the reference frame to be aligned with the International Celestial Reference System (ICRF) radio frame. Aims. W
In situ X-ray absorption spectroscopy (XAS) investigations have been performed to provide insights into the reaction mechanism of a palladium(ii) catalyzed undirected C-H acetoxylation reaction in the presence of an oxidant. A Pd(ii) N-heterocyclic carbene complex π-stacked onto reduced graphene oxide (rGO) was used as the catalyst. The Pd speciation during the catalytic process was examined by XA
Purpose: To study the feasibility of automatically identifying normal digital mammography (DM) exams with artificial intelligence (AI) to reduce the breast cancer screening reading workload. Methods and materials: A total of 2652 DM exams (653 cancer) and interpretations by 101 radiologists were gathered from nine previously performed multi-reader multi-case receiver operating characteristic (MRMC
The rarity of familial Hodgkin lymphoma (HL) has hampered detailed analyses of familial clustering. We aimed to provide the familial risk of HL by relationship, histology, age at diagnosis and sex. A cohort of 57,475 first-degree relatives of 13,922 HL patients, diagnosed between 1955 and 2009, in five European countries was followed for HL incidence. Standardized incidence ratios (SIRs) were calc
A rapid and simple approach of lactose analysis is proposed based on 3rd generation amperometric biosensors employing cellobiose dehydrogenase (CDH) from Trametes villosa or Phanerochaete sordida immobilised on screen-printed carbon electrodes (SPCEs). After optimisation of the working conditions of the biosensors - pH of the carrier buffer, flow rate and applied potential - the sensors were able
This thesis deals with tools for operational improvement of supply chain performance. The work was aimed at providing knowledge for supply chain developers and practitioners, and identifying and developing tools for improved performance in a supply chain. The investigation was part of a project financed by the European Commission called "Industrial Supply Chain Optimizer" (ISCO). The thesis consis
Stricter Swedish building regulations require a moisture-safety design process to be carried out before houses are built. In order to predict moisture-critical conditions, a properly verified, user-friendly and reliable calculation tool that could be used in this design phase, is required.This paper initially presents a blind method that could be used in order to verify heat and moisture calculati
Verksamhetsplan 2019 LU SERVICE | LUNDS UNIVERSITET Vision, uppdrag, mål, projekt och aktiviteter..................... 4 LU Service–en del av Gemensamma förvaltningen............ 6 Avdelningar ..................................................................... 8 Medarbetare................................................................... 10 Systematiskt arbetsmiljö- och riskarbete.............
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/lu_service_vp_19_webb_1.pdf - 2026-07-10
Omvärldsbevakning 2020 LUNDS UNIVERSITET | DNR STYR 2019/1832 2 OMVÄRLDSBEVAKNING 2020 Bilder av Kennet Ruona Layout och tryck av Media-Tryck, Lunds universitet Lund 2020 3OMVÄRLDSBEVAKNING 2020 Omvärldsbevakning 2020 4 OMVÄRLDSBEVAKNING 2020 Innehåll OMVÄRLDSBEVAKNING 2020..........................................................3 INLEDNING.........................................................
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/omvarldsbevakning_2020.pdf - 2026-07-10
Utvärdering av psykoterapeutprogrammet Uppdrag och sakkunniggrupp Sakkunniggruppen (se sammansättning nedan) har haft i uppdrag att utifrån Lunds universitetsgemen- samma kriterier för kvalitetssäkring och med stöd av Samhällsvetenskapliga fakultetens anvisningar och instruktioner1 utvärdera Psykoterapeutprogrammet vid Samhällsvetenskapliga fakulteten. I upp- draget ingår att lyfta lärandemiljöns
Kvalitetssäkring av kursplaner ht 2014 Juridiska fakulteten vid Lunds universitet Nämnden för utbildning på grund- och avancerad nivå Höstterminen 2014 Kvalitetssäkring av kursplaner En evaluering särskilt avseende kritiska och reflekterande perspektiv, skriftlig och muntlig färdighetsträning samt progression Författad av, amanuens Jacob Rosell Svensson amanuens Martin Andersén Innehåll 1 INLEDNIN
https://www.jur.lu.se/sites/jur.lu.se/files/2023-06/Kvalitetss%C3%A4kring%20av%20kursplaner%20ht%202014.pdf - 2026-07-10
