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We present Bioconda (https://bioconda.github.io), a distribution of bioinformatics software for the lightweight, multi-platform and language-agnostic package manager Conda. Currently, Bioconda offers a collection of over 3000 software packages, which is continuously maintained, updated, and extended by a growing global community of more than 200 contributors. Bioconda improves analysis reproducibi
This Movement Disorder Society Genetic mutation database Systematic Review focuses on monogenic atypical parkinsonism with mutations in the ATP13A2, DCTN1, DNAJC6, FBXO7, SYNJ1, and VPS13C genes. We screened 673 citations and extracted genotypic and phenotypic data for 140 patients (73 families) from 77 publications. In an exploratory fashion, we applied an automated classification procedure via a
Background: Lead-time is defined as the time by which screening advances the diagnosis compared with absence of screening. A sufficiently long lead-time needs to be achieved so that cancer can be detected while still curable. A very short lead-time may indicate poor sensitivity of the screening test, while a very long lead-time suggests overdiagnosis. Material and methods: In the first screening r
Placental malaria infection is mediated by the binding of the malarial VAR2CSA protein to the placental glycosaminoglycan, chondroitin sulfate. Recombinant subfragments of VAR2CSA (rVAR2) have also been shown to bind specifically and with high affinity to cancer cells and tissues, suggesting the presence of a shared type of oncofetal chondroitin sulfate (ofCS) in the placenta and in tumors. Howeve
The Swedish Neutron Scattering Society (SNSS) is an organization open to all those associated with Sweden who are using, or interested in the use of, neutron scattering techniques. Currently, the SNSS has around 230 members distributed all over Sweden. The SNSS is a member of the European Neutron Scattering Association (ENSA) [1], which represents the majority of the national neutron scattering so
This work presents the first data from a calculation engine for synchrotron Microbeam Radiation Therapy (MRT) implemented in the EclipseTM Treatment Planning System from Varian Medical Services. The calculation engine constitutes a simple pencil beam algorithm estimating ‘peak’ dose and of Monte Carlo simulated Peak Valley Dose Ratios (PVDRs) that are used to obtain ‘valley’ dose. The aim of this
This thesis explores the under-recognised yet symptomatic visual motif of two women, a recurring theme within a vast array of pictorial examples. Its primary objective is to construct a theoretical and methodological framework capable of comprehending the multiplicity of images in the form of an image collection: The Atlas of Two Women. This inquiry primarily draws on Walter Benjamin’s concept of
The number of devices connected to the Internet is rapidly increasing. Especially the number of Internet of Things devices. These devices contain software which, like any other software, needs to be updated. With the great amount of devices to update, this calls for a manageable updating solution which does not depend on user interaction. In this thesis we present a solution to dynamically update
The aim of this study was to optimize a function starch-ethyl cellulose film for targeting the therapeutically active substance to the colon in the disease state for patients suffering from inflammatory bowel diseases. This study includes: • The preparation of the polymeric films and the investigation of the characterization (for example mechanical properties, water uptake, dry mass loss, and mic
Sweden has seen an increased number of homeless EU citizens over the last years. There is no consensus among Swedish municipalities on how to handle the issue of housing for vulnerable EU citizens. The purpose of this thesis is to examine the right to housing and why vulnerable EU citizens cannot access the right. The issue is studied on three levels – human rights law, EU law and domestic Swedish
This master thesis was a project in cooperation with Höganäs AB. The aim was to increase the apparent density (AD) of two biomass chars, by three different agglomeration methods. The reason for the investigation is that biomass char could be used as a reducing agent in the sponge iron process at Höganäs AB. The goal was to exchange anthracite in the reduction mixture to agglomerated biomass char.
Under de senaste åren har terrorattentat i Kenya uppmärksammats och diskuterats. Efter 9/11 har Kenya blivit det land i Afrika som har klassats som en frontlinje för att bekämpa terrorismen tillsammans med USA. I samband med Kenyas terrorismbekämpning har handlingar mot somaliska flyktingar ifrågasatts och Human Rights Watch är en av de organisationer som har rapporterat om händelser under en långIn recent years, terror attacks in Kenya have been observed and discussed. After 9/11 Kenya has become the frontline of Africa, fighting terrorism alongside the United States. As a result of the fight against terrorism, questions regarding the treatment of Somalian refugees arise. Human Rights Watch is one of many organizations to rapport on such events for a period of time. With this in mind, the
This study examines the impact of sky-bridges, as an egress component, on total evacuation of a high-rise building by using an evacuation model named Pathfinder. Five scenarios, with different combination of aspects such as height of the building, number of sky-bridges (and the subsequent inter-distance between them), and people allocation have been simulated. The comparison between the results fr
Purpose: Comorbidity indices are often used to measure comorbidities in register-based research. We aimed to adapt the Charlson comorbidity index (CCI) to a Swedish setting. Methods: Four versions of the CCI were compared and evaluated by disease-specific experts. Results: We created a cohesive coding system for CCI to 1) harmonize the content between different international classification of dise
We investigate robustness properties of the Generalized Proportional Allocation (GPA) policy that has been recently proposed for traffic signal control in urban networks. The GPA policy is fully decentralized, relies only on local information on the current congestion state, and requires no knowledge of the routing, the exogenous inflows, or the network structure. In previous work, we proved throu
In this paper, we perform a belief propagation (BP) decoding threshold analysis of spatially coupled (SC) turbo-like codes (TCs) (SC-TCs) on the additive white Gaussian noise (AWGN) channel. We review Monte-Carlo density evolution (MC-DE) and efficient prediction methods, which determine the BP thresholds of SC-TCs over the AWGN channel. We demonstrate that instead of performing time-consuming MC-
We analyze a large system of globally coupled phase oscillators whose natural frequencies are bimodally distributed. The dynamics of this system has been the subject of long-standing interest. In 1984 Kuramoto proposed several conjectures about its behavior; ten years later, Crawford obtained the first analytical results by means of a local center manifold calculation. Nevertheless, many questions
