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Objectives: To compare the cost-effectiveness of the treatment of ankylosing spondylitis (AS) with infliximab in the United Kingdom over lifetime estimated from two different clinical trials and adjusted for clinical practice guidelines. Methods: A cost-effectiveness model was developed to incorporate clinical, epidemiological, and economic data and allow extrapolation of trial results and incorpo

This project was done for the company Beijer Electronics Products AB and the task was given by the hardware development department of the company. The project was about developing a concept proposal for a new generation operator panels. This was done to inspire the product developers at Beijer Electronics with innovative ideas before the actual operator panel development. More in detail the object

In less than two decades, online dating services have gone from being seen as a marginal and stigmatised practice, to being a regular activity in people's social and romantic lives. This thesis intends to examine Swedish attitudes towards the digital phenomena of online dating and online dating services. The study was conducted through a quantitative method in the form of an online survey, wit

Massive MIMO has attracted many researchers’ attention as it is a promising technology for future 5G communication systems. To characterize the propagation channels of the massive MIMO and to evaluate system performance, it is important to develop an accurate channel model for it. In this thesis, two correlative models, i.e., the Kronecker model and the Weichselberger model, and a cluster-based m

Uttrycket "fastighetspaketeringar" avser ett förfarande där en fastighet inför en kommande försäljning ”förpackas” in i ett helägt dotterbolag vartefter andelarna i dotterbolaget avyttras till en extern köpare. Genom att nyttja olika delar av lagstiftningen kan både säljaren och köparen undvika beskattningskonsekvenser. I förarbetena identifierade lagstiftaren möjligheten att paketera vä“Packaging of properties” (Sw: paketeringar av fastigheter) refers to a procedure frequently used instead of a regular property transfer when a real estate is to be sold. The real estate is first transferred to a newly established and fully owned subsidiary. Later, the shares in the subsidiary are sold to the external buyer. By using different parts of the tax legislation this method can allow bot

S:t Jacobs church and burial site from medieval Lund was excavated in 1983. There has until now not been any osteological study and there is nearly no information about the church. To gain more information about the church and the burials, an osteological study has now been made. The analysis is based on aging and sexing the skeletons to enable a socio-economic discussion. 93 out of 320 excavated

Abstract Metal oxide semiconductor (MOS) capacitor was fabricated on the InGaAs substrate with Al2O3/HfO2 gate oxide. InGaAs is one of the promising candidates for advanced applications which require the lower power supply and high frequency. The high-k films (Al2O3/HfO2) were formed by atomic layer deposition (ALD) as an alternative to silicon dioxide (SiO2) to proceed the scaling of oxide to low

Prior to the accomplishment of this research, the compatibility of the classic e-servicescape conceptual model in the context Taobao and TMall in China were rarely found among existing e-servicescape literatures due to the standardization taken by both online platforms towards the establishment of individual webshops. Meanwhile, the conceptualization of social factors as social dimension of e-serv

Background: Trust as a measure of social capital has been documented to be associated with health. Mediating factors for this association are not well investigated. Harmful alcohol consumption is believed to be one of the mediating factors. We hypothesized that low social capital defined as low institutional trust is associated with harmful alcohol consumption. Methods: Data from the 2006 Swedish

Massive MIMO, also known as very-large MIMO or large-scale antenna systems, is a new technique that potentially can offer large network capacities in multi-user scenarios. With a massive MIMO system, we consider the case where a base station equipped with a large number of antenna elements simultaneously serves multiple single-antenna users in the same time-frequency resource. So far, investigatio

Background: We evaluated the efficacy and safety of the aromatase inhibitor exemestane in patients with advanced, persistent or recurrent endometrial carcinoma. Methods: We performed an open-label one-arm, two-stage, phase II study of 25 mg of oral exemestane in 51 patients with advanced (FIGO stage III-IV) or relapsed endometrioid endometrial cancer. Patients were stratified into subsets of estro

The purpose of this phase II randomized trial was to evaluate the effect and safety of interferon-2a (IFN) in combination with extended dosing rituximab in patients with symptomatic, advanced indolent lymphoma responding to a standard single course of rituximab. Totally 123 patients were treated with rituximab 375mg/m2 once weekly for 4 weeks leading to 14 complete response (CR; 11%), 56 partial r

Background: The use of inhaled corticosteroids (ICSs) is associated with an increased risk of pneumonia in patients with COPD. However the risks of other respiratory infections such as TB and influenza remain unclear. Methods: Through a comprehensive literature search of MEDLINE EMBASE CINAHL Cochrane Library and ClinicalTrials.gov from inception to July 2013 we identified randomized controlled tr

Objectives. Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases. We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease. Methods. Blood samples from