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In the present study, we investigate the combined interaction of mesoporous silica (SiO2) and photocatalytic titanium dioxide (TiO2) nanoparticles with lipid membranes, using neutron reflectometry (NR), cryo-transmission electron microscopy (cryo-TEM), fluorescence oxidation assays, dynamic light scattering (DLS), and ζ-potential measurements. Based on DLS, TiO2 nanoparticles were found to display
Brain damage is the major cause of permanent disability and it is particularly relevant in the elderly. While most studies focused on the immediate phase of neuronal loss upon injury, much less is known about the process of axonal regeneration after damage. The development of new refined preclinical models to investigate neuronal regeneration and the recovery of brain tissue upon injury is a major
Background and AimsMRCP is used for diagnosis and follow-up of patients with primary sclerosing cholangitis (PSC). Interest in the prognostic value of MRCP is increasing. The aim of our study is to develop an MRCP-score based on cholangiographic findings previously associated with outcomes and assess its reproducibility and prognostic value in PSC.MethodsThe score (DiStrict-score) was developed ba
ObjectivesTo show feasibility of synthetic computed tomography (sCT) images generated using a commerciallyavailable software, enabling MRI-only treatment planning for the brain in a clinical setting.Patients and Methods20 and 16 patients with brain malignancies, including post-surgical cases, were included for validationand treatment, respectively. Dixon MR images of the skull were exported to the
Engaging students in active participation and collaborative learning is an important pedagogical component of teaching and learning in higher education. Teachers use a variety of activities to engage students, such as interactive lectures, presentations, group activities, and projects. A metaphorical understanding of the teaching-learning process may help in the implementation of innovative and gr
Advanced instrumentation and versatile setups are needed for understanding light interaction with biological targets. Such instruments include (1) microscopes and 3D scanners for detailed spatial analysis, (2) spectral instruments for deducing molecular composition, (3) polarimeters for assessing structural properties, and (4) goniometers probing the scattering phase function of, e.g., tissue slab
This work presents a case where a combination of electromagnetics (EM61), refraction seismic surveys and a geotechnical survey allowed a detailed mapping of the near surface at a soil depot.This work presents a case where a combination of electromagnetics (EM61), refraction seismic surveys and a geotechnical survey allowed a detailed mapping of the near surface at a soil depot. Such results together with knowledge of the glacial overburden and groundwater potential enabled accurate determination of digging depth within the area, and thereby optimizing extension of the soil depot. The
Increases in temperature related to global warming have important implications for organismal fitness. For ectotherms inhabiting temperate regions, ‘winter warming’ is likely to be a key source of the thermal variation experienced in future years. Studies focusing on the active season predict largely positive responses to warming in the reptiles; however, overlooking potentially deleterious conseq
This article reports on an investigation of audit independence in the context of local public audit in Sweden. The article focuses on the influence of two different sets of interests. The results show that there is a risk that the way the results of the audit process are communicated and disseminated in an organization is influenced by political, as well as market, interests. The article reveals t
Introduction: Induction of labor (IOL) is one of the most common obstetrical procedures, with an increasing rate. The prostaglandin E1 analogue misoprostol is frequently used as a primary method of labor induction. The optimal dose and route of administration is yet to be ascertained. Aim: To compare efficiacy and safety between a regimen of sublingually administered misoprostol and a regimen of o
For the broader industrial usage of metal additive manufactured parts, especially made by laser powder bed fusion, a better prediction and understanding of the warpage and of eigenstresses within the final part are necessary. Due to the diverse and sophisticated metallurgical and thermal processes during production, physically motivated simulations are rather complex and time consuming. Therefore,
Most studies of patents citations focus on national or international contexts, especially contexts of high absorptive capacity, and employ examiner citations. We argue that results can vary if we take the region as the context of analysis, especially if it is a region with low absorptive capacity, and if we study applicant citations and examiner-inserted citations separately. Using a sample from t
Single-chain variable fragments (scFv) are widely used in several fields. However, they can be challenging to purify unless using expensive Protein L-based affinity adsorbents or affinity tags. In this work, a purification process for a scFv using mixed-mode (MM) chromatography was developed by design of experiments (DoE) and proteomics for host cell protein (HCP) quantification. Capture of scFv f
This article describes a logistics-based framework for organizational change of service organizations. This framework is based on the key concepts of modern logistics: systems thinking for a holistic approach to business; process orientation for structure of the organization; and process management for continuous change and improvement. The development of logistics as a research and practitioner d
#077. A Marriage of Shadows, for flute (a.fl), Alto (tenor) sax, percussion, gtr, voice (2008). Premiere: ensemble Ars Nova & Angela Rademacher @ AVFest08 in Middlesbrough, UK; 2008_03_03
