Filtyp
Background: A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing the detectability of small lesions without increasing image noise. The combination of new detector technologies and new reconstruction algorithms has been found to increase image
Objective: To assess whether inter-professional, bidirectional collaboration between general practitioners (GPs) and pharmacists has an impact on improving cardiovascular risk outcomes among patients in the primary care setting. It also aimed to understand the different types of collaborative care models used. Study design: Systematic review and Hartung-Knapp-Sidik-Jonkman random effects meta-anal
IMPORTANCE: Discontinuation and nonpublication are established sources of avoidable waste among surgical trials, but rates of delayed completion and recruiting shortfalls remain unclear.OBJECTIVES: To examine the rate of delayed completion, incomplete enrollment, and discontinuation among randomized clinical trials in surgical populations and the duration of delays and extent of recruiting shortfa
BackgroundAdrenomedullin is a vasoactive hormone with potentially prognostic and therapeutic value, which mainly has been investigated in intensive care unit (ICU) settings. The triaging in the emergency department (ED) of patients to the right level of care is crucial for patient outcome.ObjectivesThe primary aim of this study was to investigate the association of bioactive adrenomedullin (bio-AD
Background: Adolescent pregnancy and associated neonatal mortality are major global health challenges. In low-income settings where 90% of the 21 million global adolescent pregnancies occur, half are unintended and a fifth experience unsafe abortion. In Kenya, Uganda, and Tanzania, the survival patterns of neonates born to adolescents are unclear.Objectives: To assess survival patterns among neona
Biogeochemical cycling of silicon (Si) in the Barents Sea is under considerable pressure from physical and chemical changes, including dramatic warming and sea ice retreat, together with a decline in dissolved silicic acid (DSi) concentrations of Atlantic inflow waters since 1990. Associated changes in the community composition of phytoplankton blooms will alter the material comprising the deposit
A major unanswered question in the dementia field is whether cognitively unimpaired individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is, amyloid-β plaques and tau neurofibrillary tangles) can preserve their cognition over time or are destined to decline. In this large multicenter amyloid and tau positron emission tomography (PET) study (n = 1,325), we examined the
Background: Environmental exposures to industrial chemicals, including perfluoroalkyl substances (PFAS), may play a role in bone development and future risk of osteoporosis. However, as prospective evidence is limited, the role of developmental PFAS exposures in bone density changes in childhood is unclear. The objective of this study was to estimate associations between serum-PFAS concentrations
Coronavirus disease (COVID-19) booster doses decrease infection transmission and disease severity. This study aimed to assess the acceptance of COVID-19 vaccine booster doses in low, middle, and high-income countries of the East Mediterranean Region (EMR) and its determinants using the health belief model (HBM). In addition, we aimed to identify the causes of booster dose rejection and the main so
Volume 2: Religious Places, Practices, and RelationsThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussioAfter the Indian Rebellion of 1857, the colonial administration in British India introduced stricter control over Indian publishers and the press printed in various indigenous languages. Newspapers in the Punjab were monitored and scrutinized from 1864 to understand “native opinions” and identify seditious tendencies. The surveillance resulted in extensive weekly press reports that were considered
Vol. 3: Migration, Representation, and ReformThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on tThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on the Sikhs in the press evolved in response to
Vol. 4: Politics of Repression and ReconciliationThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions This handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on the Sikhs in the press evolved in response to
IntroductionThere is a gap in knowledge regarding development of endometriosis and adenomyosis lesions visible at transvaginal ultrasound. The objectives were to evaluate if women with symptoms suggestive of endometriosis or adenomyosis but normal ultrasound examination develop endometriosis or adenomyosis lesions visible at ultrasound over time and if alterations of symptoms over time are associa
This is a study of a Soviet espionage mission in Sweden in 1942 under the aegis of the intelligence officer Vasilii Sidorenko. Aside from trying to reconstruct, on the basis of material filed with the archive of the Swedish Security Police (Säpo), the history of the mission, the article also addresses methodological challenges following from the fact that we must, as Soviet material remains very sThis is a study of a Soviet espionage mission in Sweden in 1942 under the aegis of the intelligence officer Vasilii Sidorenko. Aside from trying to reconstruct, on the basis of material filed with the archive of the Swedish Security Police (Säpo), the history of the mission, the article also addresses methodological challenges following from the fact that we must, as Soviet material remains very s
Background: Sit-to-stand (STS) is one of the most commonly performed functional movements in a child’s daily life that enables the child to perform functional activities such as independent transfer and to initiate walking and self-care. Children with cerebral palsy (CP) often have reduced STS ability. The aim of this study was to describe STS performance in a national based total population of ch
Purpose: This study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical therapy planning, utilizing hybrid planar-SPECT/CT imaging. Methods: Three Monte Carlo (MC) simulated digital patient phantoms were created, with time-activity data for mIBG labelled to I-123 (LEHR and ME collimators) and I-131 (HE collimator). The s
Objective: The number of type-II endometrial cancer patients has been increasing and the prognosis is not favorable. We aim to investigate whether sarcopenia index in any of several different muscles could serve as a novel biomarker of prognosis in patients with type-II endometrial cancer. Methods: We retrospectively investigated a total of 194 patients at four hospitals. Ninety patients were trea
Objectives Accumulating evidence suggested that the laminin Î 32 (LAMC2) expression level was upregulated in various cancers. However, the potential prognostic value of LAMC2 in cancers remains unclear. We conducted a meta-analysis to clarify the association of LAMC2 expression with prognosis. Design We searched Embase, Web of Science and PubMed (up to 25 November 2021) to collect all eligible stu
Introduction: We have previously adapted a clinical linear accelerator (Elekta Precise, Elekta AB) for ultra-high dose rate (UHDR) electron delivery. To enhance reliability in future clinical FLASH radiotherapy trials, the aim of this study was to introduce and evaluate an upgraded beam control system and beam tuning process for safe and precise UHDR delivery. Materials and Methods: The beam contr
Background: Continuously high rates of overdose deaths in Sweden led to the decision by the Skåne County to initiate the first regional take-home naloxone program in Sweden. The project aims to study the effect of overdose prevention education and naloxone distribution on overdose mortality in Skåne County. Secondary outcome measures include non-fatal overdoses and overdose-related harm in the gen
