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Patients with non-obstructive hypertrophic cardiomyopathy (HCM) exhibit myocardial changes which may cause flow inefficiencies not detectable on echocardiogram. We investigated whether left ventricular (LV) kinetic energy (KE) and hemodynamic forces (HDF) on 4D-flow cardiovascular magnetic resonance (CMR) can provide more sensitive measures of flow in non-obstructive HCM.Methods and resultsNinety
BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte
Negative symptoms in schizophrenia spectrum are associated with minimal treatment responses. The search for effective treatments is potentially hampered by heterogenous study-designs and sample characteristics depending on the intervention category. This PRISMA-compliant systematic review/synthesis aims to describe the literature on negative symptoms interventions for schizophrenia spectrum disord
Background and objective: Although cardiovascular toxicity from modern systemic treatments in metastatic hormone-sensitive prostate cancer (mHSPC) remains a concern, real-world data are limited. We aimed to characterise patients treated for mHSPC across multiple large cohorts and estimate cardiovascular adverse event (AE) risks. Methods: Leveraging PIONEER's Big Data platform, with databases stand
Policy on greening freight constitutes a recent addition to the discourse on sustainability in the EU. To stimulate economic growth, the EU also plans for freight transport activity to grow significantly over the coming decades. In this paper, drawing on critical discourse analysis and Marxian geographical thought, I show how the argument for implementing sustainable freight is constructed in EU f
Aim Postural orthostatic tachycardia syndrome (POTS) is a disorder with cardiovascular autonomic dysfunction where multiple and variable symptoms are common, including those from the peripheral and enteric nervous systems. We aimed to investigate subjective and objective signs of small and large fiber neuropathy in a Swedish POTS cohort compared with healthy controls. Secondly, we wanted to examin
Background: Alcohol intake increases recurrence of atrial fibrillation (AF), but its relationship with cardiovascular outcomes is less well characterized. We aimed to study the association between different levels of alcohol intake and cardiovascular outcomes in a global cohort of patients with AF. Methods: This is a cross-sectional analysis of the RE-LY AF registry, including 15,400 patients with
ObjectivesUncertainty among healthcare providers about patients’ ability to make care decisions is a barrier to shared decision-making. We aimed to assess the self-reported decision-making ability of patients with cancer at the end of life.MethodsData from 11 countries of adults with a limited life expectancy and cancer as the primary diagnosis were used. Participants completed a questionnaire, in
Background: Although it has been suggested that the hippocampus and amygdala (HA) are involved in the neurobiology of obsessive– compulsive disorder (OCD), volumetric findings have been inconsistent, and little work has been undertaken on the volumetry of the heterogeneous anatomic units of HA, with their specific functions and cytoarchitecture, in OCD. We sought to explore potential sources of he
Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S
BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world
Background: Little is known about whether the protective effect of marriage on alcohol use disorder (AUD) varies by cultural background. Aims: Using Swedish national data, we examined whether marriage is associated with a stronger reduction in AUD risk among Swedes of a Swedish background (i.e. those with two Swedish-born parents) compared to Swedes with a foreign background (i.e. one or two forei
Researcher Contact details Email: alexandra_l [dot] cermeno [at] ekh [dot] lu [dot] se Phone: +46 46 222 03 44Organisation Department of Economic History Visiting address: Scheelevägen 15 B, Lund Room number: Alfa 1:2028 Service point: 10 WebpageAlexandra L Cermeños profile in Lund University research portalOther affiliations Researcher Centre for Advanced Middle Eastern Studies (CMES) Member of S
https://www.cmes.lu.se/alexandra-l-cermeno - 2026-07-09
Postdoc Contact details Email: nitin [dot] chaudhary [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageNitin Chaudharys profile in Lund University research portalOther affiliations Researcher Department of Earth and Environmental Sciences (MGeo) Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Chan
https://www.cec.lu.se/nitin-chaudhary - 2026-07-09
Docent / Biträdande Universitetslektor Orly Siow Contact details Email: orlanda [dot] siow [at] svet [dot] lu [dot] seOrganisation Department of Political Science Service point: 31 WebpageOrlanda Siows profile in Lund University research portalResearch Areas Gender, race, and political representationGender, race and media coverage of politicsFeminist activism and coalition buildingGender and 'deve
https://www.svet.lu.se/en/orlanda-siow - 2026-07-09
Purpose: Off-target binding in the skull and meninges is observed in some subjects undergoing tau positron emission tomography (PET) and could potentially differ between men and women. In this study we elucidate sex differences in tau off-target binding using three different tau PET tracers. Methods: 541 cognitively unimpaired amyloid-β negative participants underwent tau PET using [18F]flortaucip
Background: Gun violence is a global health problem. Population-based research on firearm-related injuries has been relatively limited considering the burden of disease. The aim of this study was to analyze nationwide epidemiological trends of firearm injuries. Methods: This is a retrospective nationwide epidemiological study including all patients with firearm injuries from the Swedish Trauma Reg
Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti
BACKGROUND: Previous studies showed higher early mortality rates among patients treated with antiretroviral drugs in settings with limited resources. One of the reasons was late presentation of patients to care. With improved access to HIV services, we expect improvements in disease stage at presentation. Our objective was to assess the effect of improved availability of HIV services on patient pr
