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Background: Contemporary epidemiological studies examining incidence rates (IR) of cirrhosis and hepatocellular carcinoma (HCC) in Swedish populations are scarce. Cirrhosis and HCC are associated with a significant burden of health inequity and stigma. The importance of socioeconomic status (SES) in cirrhosis survival has scarcely been studied in Sweden. The impact of SES on HCC incidence and prog
Tuberculosis (TB) remains a major medical and public health problem throughout the world, especially in developing countries including Ethiopia. Its control program is currently being challenged by the spread of drug-resistant TB, which is the result of poor treatment outcomes. Hence, this study assessed poor adult TB treatment outcomes and associated factors in Gibe Woreda, Southern Ethiopia. An
Propionic acid (PA) is a naturally occurring short chain fatty acid produced by microbial fermentation of the indigestible foods in the intestine, having a positive effect on the gastrointestinal health. PA inhibits the growth of pathogenic bacteria and molds; hence it is widely used as preservative for food, feed and grains. It is also used as a component in several industrial products like polym
Background: Treatment of newly diagnosed acute myeloid leukaemia (AML) is based on combination chemotherapy with cytarabine (ara-C) and anthracyclines. Five-year overall survival is below 30%, which has partly been attributed to cytarabine resistance. Preclinical data suggest that the addition of hydroxyurea potentiates cytarabine efficacy by increasing ara-C triphosphate (ara-CTP) levels through
Background: There are no evidence-based recommendations on the optimal time point to initiate non-vitamin K antagonist oral anticoagulants (NOACs) after acute ischemic stroke in patients with atrial fibrillation. We aimed to investigate the efficacy and safety of early versus delayed initiation of NOAC in these patients. Methods: TIMING (Timing of Oral Anticoagulant Therapy in Acute Ischemic Strok
BackgroundRisky sexual behavior is a public health challenge that significantly affects young people’s health and well-being in Sweden and throughout the world. Moreover, poor mental health, anxiety and depression among adolescents and young adults have increased in recent years. However, although hypothesized, the associations between general mental health and risky sexual behavior among young ad
Context. White-light stellar flares are proxies for some of the most energetic types of flares, but their triggering mechanism is still poorly understood. As they are associated with strong X and ultraviolet emission, their study is particularly relevant to estimate the amount of high-energy irradiation onto the atmospheres of exoplanets, especially those in their stars’ habitable zone. Aims. We u
Diatoms, the prominent photosynthetic eucaryotes, have inhabited the world’s oceans for at least the past 120 Ma since their first appearance in the Lower Cretaceous. There are also records of older diatoms, from the Jurassic dating to ca. 172 Ma and ca. 165 Ma, however these are poorly documented. The predicted origin time of diatoms using evolutionary relationships (molecular phylogenetics) yiel
In this Master´s thesis I deal with the impact of European Community Law on chapter 57 regulations of the Swedish National Income Tax Act, IL, and regulations connected thereto. These rules specifically governs the taxation of shareholders in Swedish closely hold small and medium sized enterprises, SME:s, fåmansföretag. My purpose is thereby to investigate the principal question: whether or not ch
Background: Type 2 diabetes (T2D) and dementia represent a growing dual burden in aging populations. These conditions share pathophysiological mechanisms that may create a self-reinforcing cycle in which cognitive impairment affects diabetes management, a crucial factor for preventing complications. Despite Sweden's comprehensive care, there is limited longitudinal evidence on how cognitive
This Master’s Thesis, under the Division of Machine Design at Lund Institute of Technology, was conducted at Presona AB located in Tomelilla, Sweden during the first half of 2006. Presona AB is a leading manufacturer of equipment for handling and compression of waste. The object of the thesis is to reduce the manufacturing cost of Presona’s heavy duty stationary compactor. This is acquired by rede
Title: Retro Rewind - Unveiling the Power of Nostalgia in Fashion Retro Branding and Its Influence on the Brand Perception of Young Consumers Date of the Seminar: 31 June 2024 Course: BUSN39 Degree Project in Global Marketing Authors: Juan Bibudis and Tim Mårtensson Supervisor: Tommy Shih Examiner: Mats Urde Keywords: Nostalgia, identity, perception, Consumer Culture Theory (CCT), possessions, con
In Sweden the installed wind power has increased rapidly in recent years and the trend looks to continue. New law, in which Svenska Kraftnät will lend investment capital for expansion of grid capacity to renewable energy, will facilitate the connection of wind power plants to E.ON’s regional grid network. With more wind power connected to the grid network losses will look different.In this report,
Popular science summary Do metformin and phenformin cause toxicity to mitochondria of human blood cells? Metformin and phenformin are anti-diabetic drugs associated with lactic acidosis as a rare side effect. This side effect is thought to be due to drug-induced mitochondrial dysfunction. In this project, the mitochondrial toxicity of metformin and phenformin was assessed in human blood cells. I
Abstract Over 1000 published species which are largely heterogenous in morphology were formerly grouped in the lichen genus Caloplaca s. lat. (Ascomycota, eloschistaceae). Although there is no complete monograph of the genus, many taxonomic studies have focused on specific geographical regions. Although a number of these studies have focused on species that exist in California, samples of putativ
Popular science Boreal forests play an important role within the global climatic system, since they generally act as a carbon sink. However, contrary to expectations, measurements have shown that the boreal forest at the Norunda research site in Central Sweden is acting as a carbon source, i.e. emitting more of the greenhouse gas carbon dioxide (CO2) as taking up. Soil CO2 efflux plays an importan
Energy use and energy feedback - An evaluation of Sweden’s largest energy saving experiment at E.ON E.ON Sverige AB is now performing Sweden’s largest energy saving experiment to see if its customers can reduce their electricity consumption just by visualizing it. The experiment turns to 10 000 of E.ON’s customers, having an annual consumption exceeding 10 000 kWh. Customers are equipped with a di
An upcoming trend in the current IT-landscape is to outsource services to so called Cloud Service Providers (CSPs). However, many companies are still sceptical to this new kind of services, since they bring about a certain loss of control. For this reason, it is important for CSPs to show that their services are secure. There are several options in proving this and it is up to every CSP to choose
Background: International guidelines recommend placement of intrauterine devices immediately after second-trimester medical abortion, but evidence concerning the optimal time for intrauterine device placement is lacking from clinical trials. Objective: This study aimed to investigate effectiveness, safety, and acceptability of intrauterine device placement within 48 hours, compared with placement
[18F]Flortaucipir is an FDA-approved tau-PET tracer that is increasingly utilized in clinical settings for the diagnosis of Alzheimer’s disease. Still, a large-scale comparison of the in vivo PET uptake to quantitative post-mortem tau pathology and to other co-pathologies is lacking. Here, we examined the correlation between in vivo [18F]flortaucipir PET uptake and quantitative post-mortem tau pat
