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Background: The causes and effects of anastomotic leakage after anterior resection are difficult to study in small samples and have thus been evaluated using large population-based national registries. To assess the accuracy of such research, registries should be validated continuously. Material and methods: Patients who underwent anterior resection for rectal cancer during 2007–2013 in 15 differe
Objectives: Ncf1 polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases in animal models. The human NCF1 gene is very complex with both functional and non-functional gene copies and genotyping requires assays specific for functional NCF1 genes. We aimed at investigating association and function of the missense single nucleotide pol
Popular Abstract in Swedish Svenska lägenhetshushåll genererar i snitt 2.8-3.4 kg matavfall per vecka. Allt fler svenska kommuner har under senare år valt att införa separat insamling och biologisk behandling av matavfall. Den främsta anledningen till detta var det miljömål som syftade till att 35 % av matavfallet från hushåll, restauranger och storkök enligt riksdagens miljömål skulle behandlas bAn increased understanding of the world’s limited resources and the negative environmental impacts connected to solid waste management has in recent years increased interest in separate collection and treatment of organic waste in many parts of the world. As an example, increased biological treatment of organic waste is an explicit goal within the Swedish national solid waste management strategy (
OBJECTIVES: The aim of this study was to determine if there were any long-lasting elevated anxiety levels in women attending colposcopy after an abnormal cervical smear. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynaecology, Malmö University Hospital, Sweden. POPULATION: One hundred consecutive women were invited to participate when referred for colposcopy. METHODS: Women in
The results of numerical simulations of a positive streamer development in air in a weak and uniform electric field are presented. Streamer dynamics is considered in an electrode gap of 33 mm in length and the configuration was 'protrusion on a plate-plate'. This particular configuration was chosen in order to perform direct comparison between simulated results and experimental data. The electrost
A large-scale, high-efficiency and low-cost platform based on a Beckman Coulter Biomek FX and custom-made automation systems for structural genomics has been set up at Peking University, Beijing, People's Republic of China. This platform has the capacity to process up to 2000 genes per year for structural and functional analyses. Bacillus subtilis, a model organism for Gram-positive bacteria, and
Popular Abstract in Swedish Multikonjugerad Adaptiv Optik för Astronomiska Teleskop 1. Atmosfärisk turbulens Allt sedan man på 1600-talet började bruka optiska instrument inom astronomin, för att understödja det mänskliga ögat då man beskådade stjärnhimlen, har astronomer strävat efter att bygga allt större och bättre teleskop för att kunna se längre ut i rymden och skönja allt ljussvagare objekt.This work analyses several aspects of multi-conjugate adaptive optics (MCAO) for astronomy. The research ranges from fundamental and technical studies for present-day MCAO projects, to feasibility studies of high-order MCAO instruments for the extremely large telescopes (ELTs) of the future. The first part is an introductory exposition on atmospheric turbulence, adaptive optics (AO) and MCAO, esta
The extent of behavioral recovery following neural transplantation in part depends on the amount of surviving graft tissue. The main objective of this thesis was to study parameters affecting the survival of embryonic striatal and mesencephalic neurons in experimental models of Huntington's and Parkinson's disease. Firstly, we studied the survival and maturation of embryonic striatal neurons that
The aim of this study was to provide in vivo experimental evidence for the proposed biological significance of the creatine kinase (CK)/phosphocreatine (PCr) system in the energy metabolism of skeletal muscle. As a test system we compared hindlimb muscle of knockout mice lacking the cytosolic M-type (M-CK(-)/(-)), the mitochondrial ScMit-type (ScCKmit(-)/(-)), or both creatine kinase isoenzymes (C
Background: Up to date data on incidence, mortality, and case-fatality for stroke are important for setting the agenda for prevention and healthcare. Aims and/or hypothesis: We aim to update the most current incidence and mortality data on stroke available by country, and to expand the scope to case-fatality and explore how registry data might be complementary. Methods: Data were compiled using tw
Microsoft Word - Discovery of dopamine.doc 1 The Discovery of Dopamine Dopamine as an independent neurotransmitter in the nervous system was discovered in Lund by the pharmacologist Arvid Carlsson in 1957, working at the Department of Pharmacology at Sölvegatan 10 in Lund (the current Geocentrum building). This discovery had tremendous impact on modern neuroscience research and – in combination wi
https://www.neuroscience.lu.se/sites/neuroscience.lu.se/files/the_discovery_of_dopamine_pdf.pdf - 2026-07-25
Här och nu – att börja från början Henry Stiglund Här och nu - att börja från början Om pedagogisk utveckling inom scenframställningsämnet vid Teaterhögskolan i Malmö Konstnärligt utvecklingsarbete Maj 2010 2 Innehåll 1.Inledning ......................................................................................................................3 1.1 Att vara här och nu ...
https://www.thm.lu.se/sites/thm.lu.se/files/r05.pdf - 2026-07-25
Aims Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report from a Phase II randomized, dose-guiding study (NCT00684307) to assess safety, tolerability, pharmacokinet
Det övergripande syftet med uppsatsen är att belysa bevisproblematiken i våldtäktsmål och undersöka vissa konsekvenser av en potentiell samtyckesreglering i svensk rätt. Med traditionell rättsdogmatisk metod söker jag ge svar på hur en samtyckesreglering skulle kunna antas påverka det svåra bevisläget i våldtäktsmål. Idag regleras våldtäkt i 6 kap 1 § brottsbalken och brottet består i att någon The purpose of this essay is to shed light on the problems of proving a perpetrator guilty in rape-cases and to examine certain consequences of a future regulation based on consent. Using a traditional judicial method I have sought to answer the question of how a law of consent would affect the difficulties regarding the, from an evidential point of view, challenging position in cases concerning r
In order to study and evaluate the care provided at the Intensive Care Unit (ICU), an accurate model to assess severity of illness and predict patient mortality based on admission data is required. Since 1983, the Simplified Acute Physiology Score (SAPS) based on logistic regression (LR) has become one of the international standards for this purpose and is used in Sweden for adults. While being a
Unga lagöverträdare har sedan länge särbehandlats i det svenska påföljdssystemet. Den som begår brott innan 21 års ålder särbehandlas idag både beträffande straffmätningen och påföljdsvalet. Bland annat får den unge lagöverträdaren sitt straff reducerat genom den så kallade straffrabatten. I december 2018 utkom ungdomsreduktionsutredningen med ett förslag om slopad straffrabatt för unga lagöverträYoung offenders have long been treated differently than adult offenders in the Swedish penal system. Anyone who commits crimes before the age of 21 is today treated differently both in terms of the sentencing measure and the choice of penalty. Among other things, the young offenders gets their sentence reduced by the so-called “penalty discount”. In December of 2018 a government department issued
Straffbuden för givande respektive tagande av muta träffar ett brett spektrum av personer. Trots reformen som skett på området år 2012 är brottsbalkens bestämmelser svårtolkade och allmänt hållna. Därutöver saknas det fortfarande en legaldefinition av rekvisitet ”otillbörlig förmån” som är det rekvisit som avgränsar en tillåten förmån från en otillåten sådan. Vad som bedöms vara otillbörligt varie
Downstream processing is an essential part in the production of biomolecules and the optimization of these processes are of great value, since they can be both time consuming and expensive. One common type of enzyme used in different biotechnical approaches is proteases and in this study Protease X was investigated. In order to use the enzyme in a process, a purification procedure needs to be esta
A double-blind, randomized, placebo-controlled cross-over multi-center study was conducted to evaluate the efficacy and safety of gabapentin in the treatment of neuropathic pain caused by traumatic or postsurgical peripheral nerve injury, using doses tip to 2400 mg/day. The study comprised a run-in period of two weeks, two treatment periods of five weeks separated by a three weeks' washout period.
Spondyloarthritis (SpA) is a group of interrelated inflammatory rheumatic diseases with the sub-diagnoses ankylosing spondylitis (AS), psoriatic arthritis (PsA), arthritis-associated inflammatory bowel disease (Aa-IBD), undifferentiated SpA (USpA), where stiffness and pain are key symptoms. Insidious onset back pain, morning stiffness, waking up at night, and improvement from exercise are common c
