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Although bone marrow (BM) is the main site of natural killer (NK)-cell development in adult mice, recent studies have identified a distinct thymic-dependent NK pathway, implicating a possible close link between NK- and T-cell development in adult hematopoiesis. To investigate whether a potential NK-/T-lineage restriction of multipotent progenitors might take place already in the BM, we tested the
Galectin-1, beta-galactoside binding lectin involved in immunoregulation and cancer, binds natural and many synthetic multivalent glycoconjugates with an apparent glycoside cluster effect, that is, affinity above and beyond what would be expected from the concentration of the determinant sugar. Here we have analyzed the mechanism of such cluster effects in solution at physiological concentration u
Gut-associated lymphoid tissues (GALT) represent major sites of adaptive immune priming in the intestine, yet our understanding of human GALT diversity and function remains limited. Here, we used single-cell RNA sequencing, flow cytometry, and confocal laser microscopy to map the fibroblast (FB) landscape of human GALT, including that of Peyer's patches (PP), mucosal isolated lymphoid follicles (M
During a period of 40 years in the second half of the 17th century, a process of industrialization was initialized in the northern part of the Torne River valley, northern Sweden. The industrialization was the result of global demand for copper and brass, but its practice was a local and regional encounter between different groups of people with a manifold of identities, languages, e
BACKGROUND: Limbic-predominant age-related TDP-43 encephalopathy (LATE) clinically mimics and often co-occurs with Alzheimer's disease (AD). Expert consensus criteria have been proposed for the LATE clinical diagnosis, integrating clinical and radiological features, and AD biomarkers. Here, we applied the newly proposed criteria in a tertiary memory clinic population. METHOD: We included participa
This chapter explores how Danish animal rights activists challenge the commodification of female bodies, particularly in dairy production, through narratives of motherhood and care. It examines how activists attempt to educate the public—not only by providing information about how dairy is produced but also by offering alternative frameworks from which to think about human-cow relations. Based on
10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Forum 10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Editorial Team1,* 1Cell Stem Cell, Cell Press, 50 Hampshire Street, 5th Floor, Cambridge, MA 02139, USA *Correspondence: stemcell@cell.com http://dx.doi.org/10.1016/j.stem.2016.01.023 In an interview, we recently asked four leaders in the field to share their insights with us on th
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/10qs_ipsc.pdf - 2026-07-23
The subfamily Stiriinae (Lepidoptera, Noctuidae) is a group of ∼160 described moth species, ∼91% of which occur in the Nearctic, with species diversity centered in the deserts, grasslands, and adjacent foothills of the mountain ranges of Mexico. We infer the first species-level phylogeny for the subfamily using 8 protein-coding genes. While some lineages are primarily leaf or flower feeders, the m
Intense agricultural activity in recent years has resulted in a greater use of pesticides in order to improve productivity. However, these pesticides may contain some pollutant component in their composition. Once present in the environment and/or in excess, they can cause damage to the local flora and fauna. The aim of this study was to evaluate the interference of pesticides in the reproductive
This article examines the underexplored issue of public social protection in the artisanal and small-scale mining (ASM) sector. Social protection is defined as public actions taken in response to levels of vulnerability, risk, and deprivation considered socially unacceptable within a given society and polity. Drawing on a study of ASM in Rwanda, the article identifies a range of state-led policies
Cystatin C (CstC) is a potent cysteine-proteinase inhibitor. The structure of the mouse CstC-encoding gene (Cst3) was examined by sequencing a 6.1-kb genomic DNA containing the entire gene, as well as 0.9 kb of 5′ flanking and 1.7 kb of its 3′ flanking region. The sequence revealed that the overall organization of the gene is very similar to those of the genes encoding human CstC and other type-2
Visits to nest holes by birds other than their owners is a familiar phenomenon for students of breeding biology. In this study, we evaluate that behavior using a transponder reading system. Eighty-five males and females were Fitted with transponders at the end of the incubation period or just after hatching. Nest boxes were fitted with transponder readers from just after hatching until all nestlin
Density functional theory was employed to investigate the adsorption site and hyperfine interactions of nitric oxide adsorbed in Na-LTA (previous name NaA) zeolite. Three different cluster models of increasing complexity were used to represent the zeolite network: (1) a six-membered ring terminated by hydrogen atoms with one sodium ion above the ring, (2) as model 1 with the addition of three sodi
This paper presents a double directional analysis of vehicle-to-vehicle channel measurements conducted in three different traffic scenarios. Using a high-resolution algorithm, we derive channel parameters like Angle-of-Arrival (AOA), Angle-of-Departure (AOD), propagation delay and Doppler shift and identify underlying propagation mechanisms by combining these estimates with maps of the measurement
Popular Abstract in Swedish Min avhandling heter Knowledge and Survival in the Novels of Thomas Hardy (disputationsdag: 15 april 2000). Jag fokuserar på två sorters vetande: det traditionella, som jag kallar ‘det vardagliga’, och ‘det specialiserade’, som är knutet till modern vetenskaplig utveckling.Abstract This thesis identifies two different kinds of knowledge in Thomas Hardy's novels: the everyday, passed on from generation to generation, which is non-academic and closely bound to the local environment and its traditions; and the specialised, recorded in the printed word, which is the product of formal education and independent of the local community and its traditions. These two kinds o
Introduction For the future conservation, restoration and daily maintenance the need for developing non-destructive and in-situ investigations is vital. At Lund University in Sweden an interdisciplinary research project is being held aiming at, with the help of a mobile system of remote fluorescence lidar, survey and study the facades of historic monuments, and to develop the method and its applic
We consider demand response solutions having the capability to monitor different variables at users' premises, like presence and temperature, and to control individual appliances. We focus on the optimal control of the appliances during time periods where the available capacity is not enough to satisfy the demand generated by houses operating freely. We propose an approach to define the utility of
