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Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015
Endo-α-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) belongs to the glycoside hydrolase family GH101 and has a strict preference towards the mucin type glycan, Galβ1-3GalNAc, which is O-linked to serine or threonine residues on glycopeptides and -proteins. While other enzymes of the GH101 family exhibit a wider substrate spectrum, no GH101 member has until recently been reported to
Background: Around 70% of all ICU patients are treated with antibiotics whereas up to 30% are suggested as unnecessary. Measuring antibiotic consumption is a prerequisite to improving its use and the purpose of the present investigation was to explore the use of antibiotics in Swedish ICUs. Material and methods: Daily Defined Doses (DDDs) of antimicrobials delivered to Swedish ICUs, 2016–2018, wer
Lower severity cycling collisions, and single cyclist collisions (or single bicycle crashes) are significantly underreported in police statistics, introducing biases into the types of collisions that are available for analysis. Furthermore, many lower severity collisions do not appear in other collision data sources (e.g. hospital and insurance data). This in turn affects priorities for cyclist sa
OBJECTIVES: Early diagnosis of critical congenital heart defects (CCHD) improves survival. We evaluated the relative contributions of prenatal ultrasound, neonatal pulse oximetry screening (POS), and neonatal physical examination (NPE) to the early detection (before discharge) of CCHD in the context of increasing prenatal detection, and POS being a national standard since 2013. METHODS: Retrospect
The relative role of natural selection and genetic drift in evolution is a major topic of debate in evolutionary biology. Most knowledge spring from a small group of organisms and originate from before it was possible to generate genome-wide data on genetic variation. Hence, it is necessary to extend to a larger number of taxonomic groups, descriptive and hypothesis-based research aiming at unders
Objectives Socioeconomic disparities in smoking prevalence remain a challenge to public health. The objective of this study was to present a simple methodology that displays intersectional patterns of smoking and quantify heterogeneities within groups to avoid inappropriate and potentially stigmatising conclusions exclusively based on group averages. Setting This is a cross-sectional observational
Senior lecturer Contact details Email: felix [dot] roosen-runge [at] chem [dot] lu [dot] seOrganisation Physical Chemistry Service point: 1 WebpageFelix Roosen-Runges profile in Lund University research portalResearch interestMy central research interest addresses the mechanistic understanding of dynamics, structure and assembly in soft biological matter. My core expertise combines light, X-ray an
https://www.physchem.lu.se/felix-roosen-runge - 2026-07-09
Background: S100A9 has been shown to be important for the function of so called Myeloid Derived Suppressor Cells (MDSC). Cells with a similar phenotype are also involved in pro-inflammatory processes, and we therefore wanted to investigate the gene expression and function of these cells in animals that were either subjected to chronic inflammation, or inoculated with tumors. Methods: CD11b(+)Ly6C(
As the most figurative asset of membership in a majority or minority and the most symbolic aspect of national authority, language is a major site of struggle for majority power and minority resistance. For the purposes of this study, which focuses on the question of Kurdish linguistic rights in Turkey, the sites of struggle for majority power and minority resistance are as follows: the documents o
There are several thousands of old landfills in Sweden and they are often located close to cities on valuable land, three of these landfills are Lassabacka in Varberg, Härlövsängar in Kristianstad and Onsjöparken in Eslöv. On these landfill methane- emission and concentration measurements are done with an IR Chamber called ULTRAMAT 23, a probe and the gas analyser LFG 20. This was done to see if t
Frågan om hur man bör se på straffansvar och påföljder för personer som begår brott under inflytande av en allvarlig psykisk störning är omdebatterade och därtill mycket komplicerad. Intresset av att personer som begår brott möts av en adekvat reaktion på brottet ställs här emot behovet av att tillräckligt beakta gärningsmannens psykiska tillstånd och behov av behandling. Principen att vissa persoThe question of how one should look at penalties and sanctions for persons committing crimes under the influence of a serious mental illness is controversial and very complicated. The interest in that people who commit crimes are met with an adequate response to crime is put up against the need to sufficiently take into account the offender's mental condition and need for treatment. The princi
Title: Core values and brand promises – A mixed quantitative and qualitative study of core values, brand promises and their interdependence among 104 Fortune 500 companies. Date of the seminar: May 31, 2011 Course: BUSM08 Degree Project in International Marketing and Brand Management Authors: Per Andersson and Ola Johansson Supervisor: Associate Professor Mats Urde, PhD; Docent Keywords: Core valu
This thesis is divided into two parts (1&2) with different but related scopes, they are both partly a response to Volvo Truck Australia's (VTA) wish to improve their supply chain. In 1998 this wish resulted in a global benchmark, of VTA's total inbound transports, being submitted to 13 global transporting companies. Being one of the responding companies, Volvo Transport delegated the d
L-DOPA-induced dyskinesia is a common side effect developed after chronic treatment with 3,4-dihydroxyphenyl-L-alanine (L-DOPA) in Parkinson's disease. The biological mechanisms behind this side effect are not fully comprehended although involvement of dopaminergic, serotonergic, and glutamatergic systems has been suggested. The present study utilizes in vivo amperometry to investigate the impact
Background, aim, and scope We strive to predict consequences of genetically modified plants (GMPs) being cultivated openly in the environment, as human and animal health, biodiversity, agricultural practise and farmers' economy could be affected. Therefore, it is unfortunate that the risk assessment of GMPs is burdened by uncertainty. One of the reasons for the uncertainty is that the GMPs are int
Objective: Postprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury. Our goal was to examine the interactions between postprandial lipoproteins, LPS, and apoE3 and apoE4 on monocyte activation. Methods and Results: We showed that apoE3 complexed to phospholipi
Abstract in UndeterminedMany species of birds show evidence of secondary contact zones and subspeciation in their Scandinavian distribution range, presumably resulting from different post-glacial recolonization routes. We investigated whether this is the case also in the Scandinavian bluethroat Luscinia svecica, a species that has been suggested to consist of two separate populations: one SW-migra
