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Background Patients with primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) have a high risk of developing colorectal cancer and dysplasia. Ursodeoxycholic acid (UDCA) has been suggested to have chemopreventive effects on the development of colorectal cancer and dysplasia but long-term data and larger trials are lacking. Aim To evaluate the effect of high dose (17-23 mg/kg/d
The interest in the evaluation of health effects due to EMF has accelerated in the last decades, mostly motivated by the occupational and environmental exposures to humans by such non-ionizing fields. The increasing exposure to electromagnetic fields has been suspected to contribute to the rising incidence of cancer in industrialized countries Despite detailed analysis which provide a wealth of ac
Skiljeavtal i bilaterala investeringsskyddsavtal mellan EU-medlemsstater har sedan början på 2000-talet varit under EU-kommissionens kritiska granskning. Kommissionen anser att dessa traktater står i strid med EU-fördragen, bland annat eftersom de kan leda till att skiljenämnder tillämpar unionsrätten utanför EU-domstolens kontroll. I mars 2018 kom ett avgörande från EU-domstolen, Achmea-fallet, dArbitration agreements contained in bilateral investment treaties between EU member states have been under the EU Commission’s critical review since the beginning of the twenty-first century. The Commission considers that these treaties conflict with the EU treaties, inter alia because they may lead arbitration tribunals to apply EU law outside the control of the European Court of Justice. In Marc
We have extended our knowledge about the complexity that exists in the marketing of countries. With sweden.se as a case, we have investigated how nation branding is actually managed from a sender perspective. We have analysed which desirable values the Swedish public organization NSU (National Board for Promotion of Sweden Abroad) communicate through the website sweden.se. The results we have ar
Begreppet barnets bästa är inte något nytt begrepp inom den svenska familjerätten. Det är ett begrepp som med tiden har mognat och blivit allt mer anpassat till barnets behov. I denna uppsats ges till en början en historisk återblick kring barnets bästa och en inblick i hur utvecklingen har sett ut i den svenska rätten. Den tar också fasta på den nuvarande lagstiftningen för barnets bästa och barnThe term the best interest of the child is not a new concept in the Swedish family law. It is a concept that has developed with time and become more and more adapted to the child's needs. In this paper is initially given a retrospective about the best interests of the child and an insight into how the development has been in the Swedish law. It also takes note of the current legislation for th
IgE is responsible for type 1 mediated allergic reactions, affecting an increased part of the European population. Even though a large part of the population is affected, further being an economical burden for society, little is known about the human IgE repertoire. Variation in antibodies are mainly found in antibody variable domains, and gained understanding of the IgE repertoire can be obtained
This thesis examines the relationship between international law protecting refugees and national legislation in Sweden and in the UK. International protection is afforded by the 1951 Geneva Convention Relating to the Status of Refugees. But also general international human rights instruments are relevant. These include the Universal Declaration of Human Rights, the International Covenant on Civil
Personal computers (PC) have become an indispensable product in modern life. Along with the growing volume of computers, the environmental burden and impact at the end-of-life phase known as e-waste become significant. Considering the material-intensive nature of the production of computers, and the environmental burdens caused by landfills, incinerations and improper recycling activities, persona
Det centrala för denna uppsats är att ur ett borgenärsinriktat perspektiv utreda två alternativ för rekonstruktion av företag; företagsrekonstruktion genom FrekL och rekonstruktion genom konkurs. FrekL är en tämligen ny lag i den svenska insolvensrätten. Tidigare rekonstruktioner av företag skedde så gott som alltid genom konkurs, även om AckL fanns som alternativ. FrekL var bland annat tänkt likThe main issue in this essay is from a creditors perspective. Analysis will cover two alternatives for the reorganization of companies: First, the Swedish correspondence, “FrekL,” to the American Chapter 11 and, second, reorganization through bankruptcy. FrekL is a fairly new law within the Swedish insolvency law. Earlier reorganization of companies were almost always made through bankruptcy, ev
I denna rapport undersöks och utvärderas brandskyddet och möjligheten till utrymning vid nödsituation i Helsingborgs Arena. Undersökningen har baserats på noteringar från platsbesök, simuleringar av tänkta scenarion och kvalitativa resonemang. Utifrån dessa undersökningar har det framkommit att den största risken för människors liv vid brand i Helsingborgs Arena är vid brand i en av garderoberna In this report the fire-safety of Helsingborg Arena is analysed and evaluated. This has been done considering the safety of the people evacuating the building in case of a fire. The evaluation has been based on notes and experiences taken on a visit to the site, simulations of suggested scenarios and reasoning around possible risks and fire sources. During the progress of the work 13 different s
Ubiquitously used for monitoring pipelines and infrastructures, distributed fibre-optic acoustic sensing is becoming an emerging technology for earthquake monitoring thanks to the possibility to interrogate a large vast of distances with a dense number of sensing points in which an optical fiber cable can be retrofitted. Moreover, it can also be used as a tool by geophysicists for the characteriza
The actions and interactions of putative mediators of inflammation, such as substance P (SP), histamine, bradykinin and prostaglandins (PGE2) were studied in human skin. In addition, the effects of capsaicin were examined as it is known to release (and to deplete) SP and calcitonin gene-related peptide from C-fibres. The flare evoked by bradykinin was abolished by pretreatment with lignocaine (loc
This paper inspects the territorial and state restructuring of the globalising city-region of Tangier. It argues that recent economic growth and transnational connections follow new forms of entrepreneurial development that aggravate social and spatial inequalities. The analysis shows that these forms of urban and regional management are embedded in the neoliberalised, yet monarch-centric Moroccan
To describe outcomes, treatment and prognostic factors that influence survival of adult patients with acute lymphoblastic leukemia (ALL), who relapsed after allogeneic hematopoietic cell transplantation (HCT), we retrospectively analyzed 465 ALL adult patients from European Group for Blood and Marrow Transplantation (EBMT) centers who relapsed after a first HCT performed in complete remission (CR1
While treatment for testicular cancer (TC) has become standardized after the 1980s with an associated significant improvement in patient survival, this has been accompanied by an increased risk of second primary cancers (SPCs). Patients were identified from the Swedish Cancer Registry spanning the years from 1980 to 2015, including 8788 individuals with primary TC and their SPCs. Relative risks (R
Aim: To investigate the interobserver agreement on phenotypic early-onset ataxia (EOA) assessment and to explore whether the Scale for Assessment and Rating of Ataxia (SARA) could provide a supportive marker. Method: Seven movement disorder specialists provided independent phenotypic assessments of potentially ataxic motor behaviour in 40 patients (mean age 15y [range 5-34]; data derived from Univ
The present dissertation explores students’ perception of their own readiness for higher education and students’ study related relations and the effect on academic outcome. The complexity of student engagement and academic success means that it is relevant to conduct in-depth studies of particular student populations, to explore how certain factors play out in that specific context. First, student
